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Distigmine
go.drugbank.com/drugs/DB13694InvestigationalDistigmine is a parasympathomimetic agent with a longer duration of action and enhanced drug accumulation compared to [DB00545] and [DB01400]. … Distigmine is available in several countries as a treatment of underactive detrusor and voiding dysfunction in the urinary tract where the active ingredient is distigmine bromide.
Categories: Heterocyclic Compounds, 1-RingProducts: UBRETID TABLET 5 mg, Ubretid 5 mg - TablettenTolmetin
go.drugbank.com/drugs/DB00500ApprovedA non-steroidal anti-inflammatory agent (anti-inflammatory agents, NON-steroidal) similar in mode of action to indomethacin.
Categories: Non COX-2 selective NSAIDS, Heterocyclic Compounds, 1-RingSynonyms: 1-Methyl-5-p-toluoylpyrrole-2-acetic acid, 1-Methyl-5-(4-methylbenzoyl)-pyrrole-2-acetic acidParnaparin
go.drugbank.com/drugs/DB09260ApprovedParnaparin is an heparin of low molecular weight with antithrombotic effects.
Products: FLUXUM 0.4 ML 4250 IU 2 HAZIR SIRINGA, FLUXUM 0.4 ML 4250 IU 6 HAZIR SIRINGASulfinpyrazone
go.drugbank.com/drugs/DB01138ApprovedA uricosuric drug that is used to reduce the serum urate levels in gout therapy. It lacks anti-inflammatory, analgesic, and diuretic properties.
Categories: Cytochrome P-450 CYP2B6 Inducers, Cytochrome P-450 SubstratesSynonyms: 1,2-Diphenyl-3,5-dioxo-4-(2-phenylsulfinylethyl)pyrazolidine, 1,2-Diphenyl-4-(2'-phenylsulfinethyl)-3,5-pyrazolidinedioneFenticonazole
go.drugbank.com/drugs/DB13434InvestigationalFenticonazole has a broad spectrum of antimycotic activity against dermatophytes and yeasts.[A275048]
Categories: Heterocyclic Compounds, 1-Ring, Genito Urinary System and Sex HormonesProducts: JİNOMED 600 MG OVÜL, 2 OVÜL, GYNOKONAZOL 600 MG OVÜL, 2 ADETButenafine
go.drugbank.com/drugs/DB01091ApprovedButenafine hydrochloride is a synthetic benzylamine antifungal agent. Butenafine's mechanism of action is believed to involve the synthesis inhibition of sterols.
Synonyms: (4-tert-butylphenyl)-N-methyl-N-(naphthalen-1-ylmethyl)methanamine, N-(p-tert-butylbenzyl)-N-methyl-1-naphthalenemethylamineProducts: BUTAFLY % 1 LOSYON ,10 ML, BUTEFIN %1 KREM, 15 GFluspirilene
go.drugbank.com/drugs/DB04842ApprovedWithdrawnA long-acting injectable antipsychotic agent used for chronic schizophrenia.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesProducts: Imap Inj 2mg/ml, Imap Forte Inj 10mg/mlAlmotriptan
go.drugbank.com/drugs/DB00918ApprovedAlmotriptan is a triptan drug for the treatment of migraine headaches. Almotriptan is in a class of medications called selective serotonin receptor agonists. … It works by narrowing blood vessels in the brain, stopping pain signals from being sent to the brain, and stopping the release of certain natural substances that cause pain, nausea, and other symptoms
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C8 SubstratesSynonyms: 1-(((3-(2-(Dimethylamino)ethyl)indol-5-yl)methyl)sulfonyl)pyrrolidineIslatravir
go.drugbank.com/drugs/DB15653ApprovedInvestigational[A275492] On April 21, 2026, the FDA approved the first fixed-dose combination containing islatravir (0.25 mg) and the NNRTI doravirine (100 mg), marketed as IDVYNSO, as a complete once-daily regimen for … [A275492, L56138] Chemically, it is a deoxyadenosine analogue distinguished by a 4'-ethynyl group and a 2-fluoro substitution, which collectively enhance its metabolic stability and potency.
Categories: Heterocyclic Compounds, 2-RingSynonyms: 4'-ethynyl-2-fluoro-2'-deoxyadenosineSiponimod
go.drugbank.com/drugs/DB12371ApprovedInvestigationalIt was approved by the FDA on March 26, 2019 [L5792] and by Health Canada on February 20, 2020. … Siponimod, also known as _Mayzent_, by Novartis, is a new drug formulated for the management of Multiple Sclerosis (MS).
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C9 SubstratesProducts: MAYZENT FILM-COATED TABLET 2MG