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Displaying results 1861 - 1870 of 10000 in total
  1. Drug

    Chlorthalidone

    go.drugbank.com/drugs/DB00310
    ApprovedInvestigational

    Chlorthalidone is a thiazide-like diuretic used for the treatment of hypertension and for management of edema caused by conditions such as heart failure or renal impairment. … In addition to its antihypertensive effects, chlorthalidone has also been shown to decrease platelet aggregation and vascular permeability, as well as promote angiogenesis in vitro, which is thought to

    Mixtures: ATENOLOL CO RATIO 100/25MGCategories: Antihypertensive Agents Indicated for Hypertension, Non Potassium Sparing Diuretics
  2. Drug

    Finerenone

    go.drugbank.com/drugs/DB16165
    ApprovedInvestigational

    [A236544] So far, finerenone is the only nonsteroidal mineralocorticoid receptor antagonist to be FDA approved. … Finerenone, or BAY 94-8862, is a mineralocorticoid receptor antagonist indicated to reduce the risk of sustained decline in glomerular filtration rate, end stage kidney disease, cardiovascular death, heart

  3. Drug

    Segesterone acetate

    go.drugbank.com/drugs/DB14583
    Approved

    Segesterone acetate is a steroidal progestin or synthetic progesterone and a 19-norprogesterone derivative with no CH3 group radical in position 6 [A37048]. … It is also used as a treatment for endometriosis in South American countries. Segesterone acetate binds selectively to progesterone receptors and not androgen receptors [A37083].

    Synonyms: 16-Methylene-17-alpha-acetoxy-19-nor-4-pregnene-3,20-dioneCategories: Hormonal Contraceptives for Systemic Use
  4. Drug

    Tegaserod

    go.drugbank.com/drugs/DB01079
    ApprovedWithdrawn

    Novartis' brand name Zelnorm (tegaserod) had originally received approval from the US FDA in 2002 for the treatment of irritable bowel syndrome with constipation (IBS-C). … [L5918,F4229] Since then, closer evaluations of the original data suggesting such cardiovascular risk have resulted in the limited reintroduction or 're-approval' of tegaserod for treatment of IBS-C specifically

    Categories: Drugs for Constipation, Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome
  5. Drug

    Levomenol

    go.drugbank.com/drugs/DB13153
    Approved

    Bisabolol, or more formally α-(−)-bisabolol or also known as levomenol, (-)-alpha-Bisabolol is found in fats and oils. (-)-alpha-Bisabolol is isolated from essential oil of Matricaria chamomilla (German … chamomile) (-)-alpha-Bisabolol belongs to the family of Sesquiterpenes.

    Mixtures: Sensicutan - Salbe, NEWSTEM Rx IPL VITA C Energy AmpouleProducts: IASO White Science EX Toner, IASO White Science EX Serum
  6. Drug

    Galactose

    go.drugbank.com/drugs/DB11735
    ApprovedInvestigationalWithdrawn

    Regardless, although it is predominantly used as a pathway to generate glucose fuel for the human body, galactose is involved as an ingredient in some commonly used vaccines and non-prescription products … There are even proposals for its use in accelerating senescence in mice, rats, and Drosophila, for its association with ovarian cancer, or even for the potential treatment of focal segmental glomerulosclerosis

    Mixtures: Levovist - Pws IV (4g Granules /vial)Categories: Tests for Liver Functional Capacity
  7. Drug

    Cemiplimab

    go.drugbank.com/drugs/DB14707
    ApprovedInvestigational

    [L43867] The EMA then approved Libtayo (cemiplimab) for that indication later in the same year. [L43872] … [L43872] In October 2022, the EMA's Committee for Medicinal Products for Human Use (CHMP) recommended cemiplimab be granted marketing authorization for the treatment of cervical cancer.

  8. Indication

    Sloughing Skin

    go.drugbank.com/conditions/DBCOND0111504
    Drugs: Phentolamine
    Synonyms: Changes in skin texture
  9. Indication

    Traveler's Diarrhea

    go.drugbank.com/conditions/DBCOND0040361
    Drugs: Azithromycin · Bismuth subsalicylate · Loperamide · Norfloxacin · Ofloxacin · Rifaximin
    Synonyms: Acute Gastroenteritis in Adult Travelers
  10. Drug

    Cetalkonium

    go.drugbank.com/drugs/DB11583
    ApprovedWithdrawn

    [L2137] Cetalkonium is approved by the FDA for its use in over-the-counter products as a skin protectant.[L2737] By Health Canada, it is also approved for its use in over-the-counter products.[L1113] … [A27143] It is a quaternary ammonium salt that acts as an antiseptic against a variety of bacteria and fungi.

    Categories: Compounds used in a research, industrial, or household settingSynonyms: Cetalkonium ion