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Capsid scaffolding protein
go.drugbank.com/bio_entities/BE0001331TargetHHV-5Capsid scaffolding protein Acts as a scaffold protein by binding major capsid protein in the cytoplasm, inducing the nuclear localization of both proteins. … Autocatalytic cleavage releases the assembly protein, and subsequently abolishes interaction with major capsid protein. Cleavages products are evicted from the capsid before or during DNA packaging.
Polypeptides: Capsid scaffolding proteinSynonyms: Capsid protein P40Platelet basic protein
go.drugbank.com/bio_entities/BE0000946TargetHumansTC-1 and TC-2 are antibacterial proteins, in vitro released from activated platelet alpha-granules. CTAP-III(1-81) is more potent than CTAP-III desensitize chemokine-induced neutrophil activation
Polypeptides: Platelet basic proteinSynonyms: C-X-C motif chemokine 7Platelet factor 4
go.drugbank.com/bio_entities/BE0001129TargetHumansInteracts with thrombomodulin/THBD to enhance the activation of protein C and thus potentiates its anticoagulant activity (PubMed:9395524)
Synonyms: C-X-C motif chemokine 4Nonstructural protein 5b
go.drugbank.com/bio_entities/BE0008655TargetPolypeptides: Nonstructural protein 5bProtein O-GlcNAcase
go.drugbank.com/bio_entities/BE0005827TargetHumansDeglycosylates a large and diverse number of proteins, such as CRYAB, ELK1, GSDMD, LMNB1 and TAB1 (PubMed:28939839, PubMed:37962578). … Cleaves GlcNAc but not GalNAc from O-glycosylated proteins (PubMed:11148210, PubMed:11788610, PubMed:20673219, PubMed:22365600, PubMed:24088714, PubMed:28939839, PubMed:37962578).
Polypeptides: Protein O-GlcNAcaseFunction: [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine/L-threonine O-N-acetyl-alpha-D-glucosaminase activityNitroreductase domain-containing protein
go.drugbank.com/bio_entities/BE0003023TargetStreptococcus mutans serotype c (strain ATCC 700610 / UA159)Polypeptides: Nitroreductase domain-containing proteinSynonyms: Uncharacterized proteinProtein-glutamine gamma-glutamyltransferase 2
go.drugbank.com/bio_entities/BE0001035TargetEnzymeHumansAlso acts as a protein deamidase by mediating the side chain deamidation of specific glutamine residues of proteins to glutamate (PubMed:20547769, PubMed:9623982). … Acts as a protein-glutamine gamma-glutamyltransferase by mediating the cross-linking of proteins, such as ACO2, HSPB6, FN1, HMGB1, RAP1GDS1, SLC25A4/ANT1, SPP1 and WDR54 (PubMed:23941696, PubMed:24349085
Polypeptides: Protein-glutamine gamma-glutamyltransferase 2Synonyms: Protein G alpha(h), Protein-glutamine deamidase TGM2CREB-binding protein
go.drugbank.com/bio_entities/BE0004367TargetHumansIn addition to protein acetyltransferase, can use different acyl-CoA substrates, such as lactoyl-CoA, and is able to mediate protein lactylation (PubMed:38128537). … Also acetylates non-histone proteins, like DDX21, FBL, IRF2, MAFG, NCOA3, POLR1E/PAF53 and FOXO1 (PubMed:10490106, PubMed:11154691, PubMed:12738767, PubMed:12929931, PubMed:24207024, PubMed:28790157, PubMed
Polypeptides: CREB-binding proteinSynonyms: Protein lactyltransferas CREBBP, Protein-lysine acetyltransferase CREBBPProtein S100-A10
go.drugbank.com/bio_entities/BE0009033TargetHumansBecause S100A10 induces the dimerization of ANXA2/p36, it may function as a regulator of protein phosphorylation in that the ANXA2 monomer is the preferred target (in vitro) of tyrosine-specific kinase
Polypeptides: Protein S100-A10Synonyms: p10 protein, S100 calcium-binding protein A10Protein S100-A1
go.drugbank.com/bio_entities/BE0001090TargetHumansThese changes allow interactions with specific target proteins and modulate their activity (PubMed:22399290). … Small calcium binding protein that plays important roles in several biological processes such as Ca(2+) homeostasis, chondrocyte biology and cardiomyocyte regulation (PubMed:12804600).
Polypeptides: Protein S100-A1Synonyms: S-100 protein alpha chain, S-100 protein subunit alpha