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Vemurafenib
go.drugbank.com/drugs/DB08881ApprovedInvestigational[A31270] Vemurafenib was co-developed by Roche and Plexxikon and it obtained its FDA approval on August 17, 2011, under the company Hoffmann La Roche. … After approval, Roche in collaboration with Genentech launched a broad development program. [L1012]
Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic IndexProducts: ZELBORAF ® TABLETAS LACADAS DE 240 MGTacrolimus
go.drugbank.com/drugs/DB00864ApprovedInvestigationalIt was discovered in 1984 from the fermentation broth of a Japanese soil sample that contained the bacteria Streptomyces tsukubaensis. Tacrolimus is chemically known as a macrolide. … It reduces peptidyl-prolyl isomerase activity by binding to the immunophilin FKBP-12 (FK506 binding protein) creating a new complex.
Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic IndexProducts: PROGRAF® XL CAPSULAS DE LIBERACIONPROLONGADA DE 1 MG, PROGRAF® XL CAPSULAS DE LIBERACIONPROLONGADA DE 5 MGSodium iodide
go.drugbank.com/drugs/DB11119ApprovedInvestigationalSodium iodide is a water-soluble ionic compound with a crystal lattice. … Sodium iodide is a source of iodine and can be administered as a supplement for total parenteral nutrition [L2065] but is more commonly used in veterinary medicine.
Mixtures: De La Cruz Tincture of IodineProducts: YODURO DE SODIO NA131I SOLUCIÓNINYECTABLEAmylocaine
go.drugbank.com/drugs/DB09088ApprovedWithdrawnDespite the introduction of using cocaine injections for regional anesthesia in 1884, non-addictive substitutes were sought after immediately . Finally, in 1903 the world's first synthetic and non-addictive local anesthetic, amylocaine, ...
Products: Dentition Sirop DeD-glucose
go.drugbank.com/drugs/DB01914ApprovedInvestigationalVet approvedL-glucose is a synthesized enantiomer that is used as a low-calorie sweetener and laxative. … Its aldohexose stereoisomer, dextrose or D-glucose, is the most commonly occurring isomer of glucose in nature.
Synonyms: D-glucose, D(+)-GlucoseSalts: D-glucose monohydrateKaolin
go.drugbank.com/drugs/DB01575ApprovedKaolin is a layered silicate mineral. … Kaolin is used in ceramics, medicine, coated paper, as a food additive, in toothpaste, as a light diffusing material in white incandescent light bulbs, and in cosmetics.
Products: Dr Pore Tightening PINK CLAY FACIAL MASK, Dr Pore Tightening GLACIAL CLAY FACIAL MASKMilk thistle
go.drugbank.com/drugs/DB14375ApprovedInvestigationalMilk thistle is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Products: Dr. Super KhanCetyl alcohol
go.drugbank.com/drugs/DB09494ApprovedCetyl alcohol is reported to be a mild skin or eye irritant. … According to the FDA Code of Federal Regulations, cetyl alcohol is a safe synthetic fatty acid in food and in the synthesis of food components under the condition that it contain not less than 98 percent
Products: All Day Skin Relief with Colloidal OatsHyaluronic acid
go.drugbank.com/drugs/DB08818ApprovedInvestigationalVet approvedHyaluronic acid (HA) is an anionic, nonsulfated glycosaminoglycan found in connective, epithelial, and neural tissues; it was first isolated in 1934. … [A230133] Several preparations of hyaluronic acid have been approved by the FDA and are available in oral, topical, and injectable forms.
Mixtures: HUMYLUB OFTENO - LIBRE DE CONSERVADORES, OUHOE Retinol Collagen Complex Day Night CreamCategories: Compounds used in a research, industrial, or household settingOxidronic acid
go.drugbank.com/drugs/DB14159ApprovedProducts: OSTEOCIS KIT PARA PREPARACIÓNDE OXIDRONATO DE TECNECIO ( 99M TC)