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Vepdegestrant
go.drugbank.com/drugs/DB19006ApprovedInvestigational[A275508, A275509] On May 1, 2026, the FDA granted approval for vepdegestrant tablets under the trade name VEPPANU. … [A275508] Specifically, vepdegestrant is being developed as a first-line or subsequent treatment option for patients whose tumors grow in response to estrogen and have progressed after standard therapies
Beeswax
go.drugbank.com/drugs/DB11600ApprovedThe wax obtained from the honeycomb of the bee. It consists primarily of myricyl palmitate, cerotic acid esters and some high-carbon paraffins.
Chronic Phase Chronic Myeloid Leukemia
go.drugbank.com/conditions/DBCOND0057382Synonyms: Chronic myelogenous leukemia, no International Classification of Diseases for Oncology subtypeValoctocogene roxaparvovec
go.drugbank.com/drugs/DB15561ApprovedInvestigationalWithdrawn[L43282,A252807] Valoctocogene roxaparvovec was approved by EMA in September 2022 and is indicated for the treatment of severe hemophilia A. It is not approved for use in the United States. … Valoctocogene roxaparvovec is an adeno-associated virus serotype 5 (AAV5) based gene therapy vector that expresses the B-domain deleted SQ form of human coagulation factor VIII (hFVIII-SQ).
Tebipenem pivoxil
go.drugbank.com/drugs/DB16840Approved[L57979] Carbapenems are the standard treatment for severe or resistant Gram-negative infections but had until now been available only intravenously, meaning patients with resistant complicated urinary … [L57979,L57980] It retains activity against many extended-spectrum beta-lactamase producers but not against organisms producing serine or metallo-carbapenemases.
Categories: Antibacterials for Systemic Use, Antiinfectives for Systemic UsePapaverine
go.drugbank.com/drugs/DB01113ApprovedInvestigationalAn alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions. … It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, especially for cerebral vasodilation.
Categories: Drugs for Functional Gastrointestinal DisordersHaloprogin
go.drugbank.com/drugs/DB00793ApprovedWithdrawnHaloprogin is a halogenated phenolic ether administered topically for dermotaphytic infections. … The mechanism of action is unknown, but it is thought to be via inhibition of oxygen uptake and disruption of yeast membrane structure and function.
Categories: Antifungals for Topical Use, Antifungals for Dermatological UseFomivirsen
go.drugbank.com/drugs/DB06759ApprovedWithdrawnFomivirsen is marketed under the trade name Vitravene for intravitreal injection and was the first antisense drug to be approved by the Food and Drug Administration (FDA). … The drug was withdrawn by the FDA because while there was a high unmet need for drugs to treat CMV when the drug was initially discovered and developed due to the CMV arising in people with AIDS, the development
Categories: Compounds used in a research, industrial, or household settingTebentafusp
go.drugbank.com/drugs/DB15283ApprovedInvestigational[L39995] Tebentafusp was subsequently approved for the same indication in the EU in April 2022.[L41675] … [A244815] On January 26, 2022, tebentafusp was first approved by the FDA for the treatment of HLA-A*02:01-positive adults with unresectable or metastatic uveal melanoma.
Interferon alfa-n1
go.drugbank.com/drugs/DB00011ApprovedWithdrawnThis differs from recombinant alpha interferons, which are individual non-glycosylated proteins produced from individual alpha interferon genes. … Interferon alfa-n1 consists of purified, natural (n is for natural) alpha interferon subtypes, at least two of which are glycosylated.