Search

Displaying results 1901 - 1910 of 10000 in total
  1. Target

    Serine/threonine-protein kinase Nek5

    go.drugbank.com/bio_entities/BE0009499
    TargetHumans

    Synonyms: Never in mitosis A-related kinase 5
  2. Target

    Chloride anion exchanger

    go.drugbank.com/bio_entities/BE0010211
    TransporterHumans

    Plays a role in the chloride and bicarbonate homeostasis during sperm epididymal maturation and capacitation (By similarity) … Mediates chloride-bicarbonate exchange with a chloride bicarbonate stoichiometry of 2:1 in the intestinal epithelia (PubMed:16606687, PubMed:19321737, PubMed:22159084, PubMed:22627094).

    Synonyms: Down-regulated in adenoma
  3. Target

    Serine/threonine-protein kinase Nek7

    go.drugbank.com/bio_entities/BE0017593
    TargetHumans

    Protein kinase which plays an important role in mitotic cell cycle progression (PubMed:17101132, PubMed:19941817, PubMed:31409757).

    Synonyms: Never in mitosis A-related kinase 7
  4. Target

    Mitochondrial peptide methionine sulfoxide reductase

    go.drugbank.com/bio_entities/BE0000170
    TargetEnzymeHumans

    Plays a crucial role in repairing oxidized methionine residues in key lens proteins, such as alpha-crystallin (CRYAA/CRYAB) and cytochrome c (CYCS), thereby restoring their function and maintaining lens … Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

    Synonyms: Peptide Met(O) reductase
  5. Target

    Peptide methionine sulfoxide reductase MsrA

    go.drugbank.com/bio_entities/BE0001618
    TargetShigella flexneri

    Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity).

    Synonyms: Peptide Met(O) reductase
  6. Drug

    Serine

    go.drugbank.com/drugs/DB00133
    ApprovedInvestigationalNutraceutical

    A non-essential amino acid occurring in natural form as the L-isomer. It is synthesized from glycine or threonine. It is involved in the biosynthesis of purines; pyrimidines; and other amino acids.

    Mixtures: Aminosyn II in Dextrose, Aminosyn II in DextroseSynonyms: (S)-2-Amino-3-hydroxypropanoic acid, L-Serine
  7. Indication

    Osteoarthritis (OA)

    go.drugbank.com/conditions/DBCOND0056529
    Drugs: Aceclofenac · Acetaminophen · Benzyl nicotinate · Bupivacaine · Capsaicin · Celecoxib +36 more
    Synonyms: O/A
  8. Drug

    Camizestrant

    go.drugbank.com/drugs/DB19218
    ApprovedInvestigational

    [L64117,L64107,L64116] It is the first next-generation oral SERD and complete ER antagonist approved in the first-line setting, and the only one approved for use with all three widely approved CDK4/6 inhibitors … [L64094,L64107] Patients are selected for treatment on the basis of an *ESR1* mutation detected by circulating tumor DNA testing during first-line endocrine therapy, before radiographic disease progression

    Synonyms: 3-pyridinamine, n-(1-(3-fluoropropyl)-3-azetidinyl)-6-((6s,8r)-6,7,8,9-tetrahydro-8-methyl-7-(2,2,2-trifluoroethyl)-3h-pyrazolo(4,3-f)isoquinolin-6-yl)-, N-(1-(3-fluoropropyl)-3-azetidinyl)-6-((6s,8r)-8-methyl-7-(2,2,2-trifluoroethyl)-6,7,8,9-tetrahydro-3h-pyrazolo(4,3-f)isoquinolin-6-yl)-3-pyridinamineCategories: P-glycoprotein inhibitors, P-glycoprotein substrates
  9. Drug

    Sennosides

    go.drugbank.com/drugs/DB11365
    ApprovedInvestigational

    Sennoside A, one of the sennosides present in the laxative medication, has recently proven effective in inhibiting the ribonuclease H (RNase H) activity of human immunodeficiency virus (HIV) reverse transcriptase … The medication is taken by mouth or via the rectum[FDA Label]. It typically begins working in minutes when given by rectum and within twelve hours when given by mouth[FDA Label].

    Salts: Sennosides A and BMixtures: 2 In 1laxative Stool Softener and Stiulant Laxative, 2 In 1laxative Stool Softener and Stiulant Laxative
  10. Indication

    Juvenile Cataracts

    go.drugbank.com/conditions/DBCOND0135843
    Drugs: Bendazac
    Synonyms: Cataract in Child