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Cerliponase alfa
go.drugbank.com/drugs/DB13173ApprovedInvestigational[L51339] It was also approved by the EMA on May 30, 2017 [L51324] and by Health Canada on December 19, 2018. … [L51329] CLN2 is a predominantly pediatric-onset neurodegenerative disease caused by a deficiency in the lysosomal enzyme TPP1, leading to progressive impairment in motor and cognitive function.
Categories: Enzymes and Coenzymes, Alimentary Tract and MetabolismFerric hydroxide
go.drugbank.com/drugs/DB13423InvestigationalCategories: Blood and Blood Forming OrgansProducts: NOGİSFER 100MG/5 ML ORAL ÇÖZELTİ, 100 MLSeizure Disorder, Post Traumatic
go.drugbank.com/conditions/DBCOND0106759Drugs: PhenytoinSynonyms: Epilepsy due to and following traumatic brain injury, Epilepsy due to and following traumatic brain injury (disorder)Tixagevimab
go.drugbank.com/drugs/DB16394ApprovedInvestigational[A243356, A243361] Tixagevimab (formerly AZD8895) is a recombinant monoclonal antibody produced in Chinese hamster ovary (CHO) cells derived from a neutralizing antibody isolated from a patient with a … [A243351, A243361, L39411] Tixagevimab is not approved for any indication by the FDA.
Categories: tixagevimab and cilgavimab, Amino Acids, Peptides, and ProteinsObesity
go.drugbank.com/conditions/DBCOND0015947Drugs: Amphetamine · Benzphetamine · Bupropion · Fluoxetine · Lecithin, soybean · Lorcaserin +6 moreSynonyms: Overweight and obesityEmtricitabine
go.drugbank.com/drugs/DB00879ApprovedInvestigationalreverse transcriptase inhibitor (NRTI) indicated for the treatment of HIV infection in adults[L9019] or combined with [tenofovir alafenamide] for the prevention of HIV-1 infection in high risk adolescents and … [L9019] The drug works by inhibiting HIV reverse transcriptase, preventing transcription of HIV RNA to DNA.[L9019] Emtricitabine was granted FDA approval on 2 July 2003.[L9019]
Mixtures: ODEFSEY FILM-COATED TABLET 200MG/25MG/25MG, GENVOYA 150MG/150MG/200MG/10MG FILM KAPLI TABLET, 90 ADETCategories: tenofovir disoproxil and emtricitabine, emtricitabine and tenofovir alafenamideMepyramine
go.drugbank.com/drugs/DB06691ApprovedVet approvedIt has been found in over-the-counter combination products for colds and menstrual symptoms, but is considered to be an unapproved prescription medication used for cough, cold, or allergic conditions. … However, it rapidly permeates the brain and so often causes drowsiness as a side effect.
Mixtures: Acetaminophen,Caffeine and Pyrilamine Maleate, Pyrilamine Maleate and Phenylephrine HydrochlorideCategories: Hypnotics and SedativesNirsevimab
go.drugbank.com/drugs/DB16258ApprovedInvestigational[L44146] Nirsevimab was also approved by Health Canada on April 19, 2023 and by the FDA in July 17, 2023 for the same indication.[L46392,L47461] … [A254571,L44146] On November 2022, nirsevimab was approved by the EMA for the prevention of RSV lower respiratory tract disease in newborns and infants.
Categories: Amino Acids, Peptides, and Proteins, Immune Sera and ImmunoglobulinsElectrolyte imbalance
go.drugbank.com/conditions/DBCOND0015850Synonyms: Disorder of fluid AND/OR electrolyte (disorder), Disorders of fluid, electrolyte and acid-base balanceCobicistat
go.drugbank.com/drugs/DB09065ApprovedInvestigationalAlthough it does not have any anti-HIV activity, cobicistat acts as a pharmacokinetic enhancer by inhibiting cytochrome P450 3A isoforms (CYP3A) and therefore increases the systemic exposure of coadministered … agents that are metabolized by CYP3A enzymes.
Mixtures: STRIBILD 150MG/150MG/200MG/245MG FILM KAPLI TABLET, 90 ADET, STRIBILD 150MG/150MG/200MG/245MG FILM KAPLI TABLET, 30 ADETCategories: darunavir and cobicistat, atazanavir and cobicistat