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Pipemidic acid
go.drugbank.com/drugs/DB13823InvestigationalPipemidic acid is a quinolone antibacterial agent with activity against various gram-positive and gram-negative bacteria.[A275138, A275143]
Categories: Heterocyclic Compounds, 1-Ring, Cytochrome P-450 CYP1A2 InhibitorsProducts: ACIDO PIPEMIDICO DR. REDDY'S, MIXATO® 400 MG TABLETASCell growth-regulating nucleolar protein
go.drugbank.com/bio_entities/BE0008958TargetMousePrevents NCL self-cleavage, maintaining a normal steady-state level of NCL protein in undifferentiated embryonic stem cells (ESCs), which in turn is essential for ESC self-renewal (PubMed:19489080). … In addition, inhibits NF-kappa-B-mediated expression of pro-inflammatory cytokines (By similarity).
Synonyms: Protein expressed in male leptotene and zygotene spermatocytes 264Serine/threonine-protein kinase Nek3
go.drugbank.com/bio_entities/BE0009497TargetHumansRegulates microtubule acetylation in neurons. Contributes to prolactin-mediated phosphorylation of PXN and VAV2. … Implicated in prolactin-mediated cytoskeletal reorganization and motility of breast cancer cells through mechanisms involving RAC1 activation and phosphorylation of PXN and VAV2
Synonyms: Never in mitosis A-related kinase 3Relacorilant
go.drugbank.com/drugs/DB14976ApprovedInvestigational[L56089] Relacorilant was approved by the US FDA on March 25, 2026, for use in combination with [paclitaxel] in patients with certain platinum-resistant cancers.[L56093,L56089] … in the context of resistant cancers.
Categories: Cytochrome P-450 CYP1A2 Inducers, Cytochrome P-450 CYP2C8 InducersGlofitamab
go.drugbank.com/drugs/DB16371ApprovedInvestigational[L45698,A258488] Glofitamab was approved by Health Canada in March 2023 for the treatment of certain patients with relapsed or refractory diffuse large B-cell lymphoma (DLBCL), becoming the first CD20 … ) after two or more lines of systemic therapy.
Categories: Bispecific CD20-directed CD3 T Cell EngagerAspartic acid
go.drugbank.com/drugs/DB00128ApprovedInvestigationalNutraceuticalOne of the non-essential amino acids commonly occurring in the L-form. It is found in animals and plants, especially in sugar cane and sugar beets. It may be a neurotransmitter.
Mixtures: Aminosyn II 7% M In 10% Dextrose(dual Chamber), Aminosyn II in DextroseSynonyms: D, (S)-2-aminosuccinic acidArylamine N-acetyltransferase 2
go.drugbank.com/bio_entities/BE0003607EnzymeHumansCatalyzes the N- or O-acetylation of various arylamine and heterocyclic amine substrates (PubMed:12222688, PubMed:7915226). … Participates in the detoxification of a plethora of hydrazine and arylamine drugs, and is able to bioactivate several known carcinogens
Synonyms: N-hydroxyarylamine O-acetyltransferaseBack pain
go.drugbank.com/conditions/DBCOND0115953Drugs: Acetaminophen · Borneol · Camphor · Capsaicin · Choline salicylate · Chondroitin sulfate +11 moreSynonyms: Pain in backArginine
go.drugbank.com/drugs/DB00125ApprovedInvestigationalNutraceuticalAn essential amino acid that is physiologically active in the L-form.
Synonyms: (S)-2-amino-5-guanidinopentanoic acid, (S)-2-Amino-5-guanidinovaleric acidInternational brands: R-Gene 10Cipaglucosidase alfa
go.drugbank.com/drugs/DB16708ApprovedInvestigational,[L45275] and the EMA fully approved the drug on March 27, 2023. … Cipaglucosidase alfa is conjugated with mannose-6-phosphate (M6P) N-glycans that bind to the cation-independent mannose-6-phosphate receptor (CI-MPR) in skeletal muscle, one of the main affected tissues
Synonyms: Recombinant human acid alpha-glucosidase optimized for high expression of mannose 6-phosphate