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Displaying results 11 - 20 of 30 in total
  1. Drug

    Anastrozole

    go.drugbank.com/drugs/DB01217
    ApprovedInvestigational

    Anastrozole is a non-steroidal aromatase inhibitor (AI), similar to letrozole, used to decrease circulating estrogen levels in the treatment of postmenopausal women with estrogen-responsive breast cancer. Anastrozole is also related to e...

    Products: KEYFEN
  2. Drug

    Piroxicam

    go.drugbank.com/drugs/DB00554
    ApprovedInvestigational

    A cyclooxygenase inhibiting, non-steroidal anti-inflammatory agent (NSAID) that is well established in treating rheumatoid arthritis and osteoarthritis and used for musculoskeletal disorders, dysmenorrhea, and postoperative pain. Its lon...

    Products: VERAN-D, VERAN D® CAPSULAS 20 MG
  3. Drug

    Ondansetron

    go.drugbank.com/drugs/DB00904
    ApprovedInvestigationalWithdrawn

    A competitive serotonin type 3 receptor antagonist. It is effective in the treatment of nausea and vomiting caused by cytotoxic chemotherapy drugs, including cisplatin, and has reported anxiolytic and neuroleptic properties. Having been ...

    Products: VOMCERAN, Ondansetron Tenshi Kaizen 4 mg Schmelztabletten
  4. Target

    4-hydroxy-tetrahydrodipicolinate reductase

    go.drugbank.com/bio_entities/BE0001983
    TargetMycobacterium tuberculosis

    Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (Probable). Can use both NADH and NADPH as a reductant, with NADH being 6-fold as effective as NADPH.

    Synonyms: HTPA reductase
  5. Target

    4-hydroxy-tetrahydrodipicolinate synthase

    go.drugbank.com/bio_entities/BE0001460
    TargetThermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)

    Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).

    Synonyms: HTPA synthase
  6. Target

    4-hydroxy-tetrahydrodipicolinate reductase

    go.drugbank.com/bio_entities/BE0001986
    TargetEscherichia coli (strain K12)

    Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate. Can use both NADH and NADPH as a reductant, with NADH being twice as effective as NADPH.

    Synonyms: HTPA reductase
  7. Target

    ATP-dependent protease ATPase subunit HslU

    go.drugbank.com/bio_entities/BE0003289
    TargetShigella flexneri

    ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. Hsl...

    Synonyms: htpI
  8. Indication

    Degenerative Joint Disease of Hip

    go.drugbank.com/conditions/DBCOND0110588
    Drugs: Diacerein
    Synonyms: OA hips, Hips osteoarthritis
  9. Drug

    Ketoconazole

    go.drugbank.com/drugs/DB01026
    ApprovedInvestigational

    Ketoconazole is an imidazole antifungal agent used in the prevention and treatment of a variety of fungal infections.[FDA Label] It functions by preventing the synthesis of ergosterol, the fungal equivalent of cholesterol, thereby increa...

    Products: KOFEN
  10. Drug

    Serotonin

    go.drugbank.com/drugs/DB08839
    InvestigationalNutraceutical

    For temporary relief of nervousness, anxiety, mood swings, joint pains, weakness, drowsiness, itching and lethargy. Not evaluated by the FDA, homeopathic product.

    International brands: 5-HTP, HTP Calm