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Bromazepam Action Pathway
smpdb.ca/view/SMP0125070Drug actionBromazepam is a short-acting benzodiazepine with intermediate onset commonly used to treat panic disorders and severe anxiety. … According to many psychiatric experts, Bromazepam has a greater abuse potential than other benzodiazepines because of fast resorption and rapid onset of action.
Enzymes: Vesicular inhibitory amino acid transporter, Gamma-aminobutyric acid type B receptor subunit 2Zolpidem Action Pathway (New)
smpdb.ca/view/SMP0125072Drug actionZolpidem binding to the GABAA receptor chloride channel macromolecular complex is thought to lead to the sedative, anticonvulsant, anxiolytic, and myorelaxant drug effects of the drug. … This binding will result in an increase on the GABA inhibitory effects which is translated as an increase in the flow of chloride ions into the cell causing hyperpolarization and stabilization of the cellular
Enzymes: Vesicular inhibitory amino acid transporter, Gamma-aminobutyric acid type B receptor subunit 2Triazolam Action Pathway
smpdb.ca/view/SMP0126116Drug actionThese receptors are thought to be coupled to gamma-aminobutyric acid-A (GABAA) receptors, this enhances the effects of GABA by increasing GABA affinity for the GABA receptor. … This drug binds to various regions of the brain and spinal cord where GABA A receptors are.
Enzymes: Vesicular inhibitory amino acid transporter, Gamma-aminobutyric acid type B receptor subunit 2Chlordiazepoxide Action Pathway
smpdb.ca/view/SMP0126120Drug actionChlordiazepoxide is a benzodiazepine used to treat the withdrawal symptoms of acute alcoholism, to treat preoperative anxiety, and to treat anxiety over a short term period. … Some side effects of using chlordiazepoxide may include drowsiness, dizziness, and weakness.
Drugs: Pyridoxal phosphate · Glutamic acid · ATP · Chlordiazepoxide · Calcium · Magnesium cation +3 moreEnzymes: Vesicular inhibitory amino acid transporter, Gamma-aminobutyric acid type B receptor subunit 2Flurazepam Action Pathway
smpdb.ca/view/SMP0126129Drug actionusers to drive safely and increase risks of falls and hip fractures. … Furthermore, it decreases sleep latency and number of awakenings for a consequent increase in total sleep time. Flurazepam binds to an allosteric site on GABA-A receptors.
Enzymes: Vesicular inhibitory amino acid transporter, Gamma-aminobutyric acid type B receptor subunit 2Butalbital Action Pathway
smpdb.ca/view/SMP0126149Drug actionButalbital, or 5-allyl-5-isobutylbarbituric acid, is a derivative of barbituric acid which the hydrogens at position 5 are substituted by an allyl group and an isobutyl group. … Typically indicated to manage tension (or muscle contraction) headaches, butalbital is often combined with one or more therapeutic agents, such as acetylsalicylic acid, acetaminophen, aspirin, and caffeine
Enzymes: Vesicular inhibitory amino acid transporter, Gamma-aminobutyric acid type B receptor subunit 2Flumazenil Action Pathway
smpdb.ca/view/SMP0126152Drug actionSome side effects of using flumazenil may include headache, dizziness, nausea, and flushing. … Fumazenil is an imidazobenzodiazepine derivative and a potent benzodiazepine receptor antagonist that competitively inhibits the activity at the benzodiazepine recognition site on the GABA/benzodiazepine
Enzymes: Vesicular inhibitory amino acid transporter, Gamma-aminobutyric acid type B receptor subunit 2Halothane GABA(A) Anesthetic Action Pathway
smpdb.ca/view/SMP0126161Drug actionHalothane's effect are also likely due to binding to NMDA and calcium channels, causing hyperpolarization. … It also acts as an NMDA receptor antagonist, inhibits nACh and voltage-gated sodium channels, and activates 5-HT3 and twin-pore K+ channels.
Enzymes: Vesicular inhibitory amino acid transporter, Gamma-aminobutyric acid type B receptor subunit 2Sevoflurane GABA(A) Anesthetic Action Pathway
smpdb.ca/view/SMP0126170Drug actionThis ability to modulate ion channel activity can also regulate cardiac excitability and contractility. … Sevoflurane is three times more potent than desflurane, but has lower potency compared to halothane and isoflurane.
Enzymes: Vesicular inhibitory amino acid transporter, Gamma-aminobutyric acid type B receptor subunit 2Thiopental Action Pathway
smpdb.ca/view/SMP0126813Drug actionAdministered intravenously, this barbiturate is employed to induce general anesthesia promptly, achieve temporary complete anesthesia, induce hypnosis, and control convulsive conditions. … It has been shown that low doses can counteract analgesia and lower the pain threshold.
Enzymes: Vesicular inhibitory amino acid transporter, Gamma-aminobutyric acid type B receptor subunit 2