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Displaying results 191 - 200 of 104418 in total
  1. Target

    Type I iodothyronine deiodinase

    go.drugbank.com/bio_entities/BE0009854
    EnzymeTargetHumans

    Plays a crucial role in the metabolism of thyroid hormones (TH) and has specific roles in TH activation and inactivation by deiodination (PubMed:12586771, PubMed:32718224, PubMed:18821722). Catalyzes the deiodination of L-thyroxine (T4) ...

    Polypeptides: Type I iodothyronine deiodinaseSynonyms: Type-I 5'-deiodinase
  2. Drug

    Medroxyprogesterone acetate

    go.drugbank.com/drugs/DB00603
    ApprovedInvestigational

    [A14848] MPA can be use to treat secondary amenorrhea, endometrial hyperplasia, abnormal uterine bleeding, osteoporosis, vasomotor symptoms in menopause, vulvar and vaginal atrophy, prevent pregnancy, … Medroxyprogesterone acetate (MPA) is a [progesterone] derivative that is more resistant to metabolism for improved pharmacokinetic properties.

    Mixtures: OBAT SUNTIK KB II, DIVICONT TABLETAS 1 MG/5 MGCategories: Pregnen (4) Derivatives, P-glycoprotein inhibitors
  3. Drug

    Zinc citrate

    go.drugbank.com/drugs/DB11154
    ApprovedInvestigational

    Zinc citrate is a zinc salt of citric acid. It is available as dietary supplements as a treatment of zinc deficiency and source of zinc, which is an essential trace element.

    Mixtures: Cal-mag (one To One) With Potass & Zinc, Cal-mag Complete With Zinc, C and DProducts: Zincitrate Cap 30mg, Zinc Citrate - Cap 30mg
  4. Drug

    Nitrofurantoin

    go.drugbank.com/drugs/DB00698
    ApprovedInvestigationalVet approved

    [L6856,L6859,L6862] Nitrofurantoin is converted by bacterial nitroreductases to electrophilic intermediates which inhibit the citric acid cycle as well as synthesis of DNA, RNA, and protein. … [A179824] This drug is more resistant to the development of bacterial resistance because it acts on many targets at once.

    Categories: P-glycoprotein substrates, Heterocyclic Compounds, 1-RingSynonyms: N-(5-Nitrofurfurylidene)-1-aminohydantoin, 1-((5-nitro-2-furanyl)methylene)amino-2,4-imidazolidenedione
  5. Drug

    Adenosine

    go.drugbank.com/drugs/DB00640
    ApprovedInvestigational

    [A229828] Adenosine is indicated as an adjunct to thallium-201 in myocardial perfusion scintigraphy,[L31983] though it is rarely used in this indication, having largely been replaced by [dipyridamole] … The structure of adenosine was first described in 1931,[A229823] though the vasodilating effects were not described in literature until the 1940s.

    Mixtures: Lebody Bu W Renewal Up, Ginseng Royal Silk Cap Sule EssenceCategories: Antiarrhythmics, Class V, Heterocyclic Compounds, 2-Ring
  6. Drug

    Nicotinamide

    go.drugbank.com/drugs/DB02701
    ApprovedInvestigational

    An important compound functioning as a component of the coenzyme NAD. Its primary significance is in the prevention and/or cure of blacktongue and pellagra. … Most animals cannot manufacture this compound in amounts sufficient to prevent nutritional deficiency and it therefore must be supplemented through dietary intake.

    Synonyms: 3-pyridinecarboxamide, β-pyridinecarboxamideMixtures: Lebody Bu W Renewal Up, Ouhi Cell Power No 1 Essence
  7. Drug

    Valerian

    go.drugbank.com/drugs/DB13196
    Approved

    Valerian is extracted from a herb that is a perennial flowering plant. Valerian root is reported to have sedative and anxiolytic effects however its mechanism of action is not completely understood. … Valerian is a food ingredient permitted for direct addition to food for human consumption as a natural flavoring substance.

    Mixtures: Bio-strath No. 8 Gouttes, Herbal Slumber CapCategories: Cytochrome P-450 CYP2C19 Inducers, Cytochrome P-450 CYP3A Inducers
  8. Target

    Keratin, type I cytoskeletal 16

    go.drugbank.com/bio_entities/BE0009086
    TargetHumans

    Structural component of intermediate filaments in epithelial keratinocytes. Forms heteropolymers with type II keratins KRT6A and KRT6B, assembling into keratin intermediate filament networks that contribute to cytoskeletal resilience of ...

    Polypeptides: Keratin, type I cytoskeletal 16
  9. Indication

    Stage I Mycosis Fungoides

    go.drugbank.com/conditions/DBCOND0080285
    Drugs: Mechlorethamine
    Synonyms: Stage I Mycosis Fungoides, Mycosis fungoides stage I
  10. Drug

    alpha-Tocopherol acetate

    go.drugbank.com/drugs/DB14003
    Approved

    Alpha-tocopherol is the primary form of vitamin E that is preferentially used by the human body to meet appropriate dietary requirements. … This biologic action of vitamin E consequently continues to generate ongoing interest and study in whether or not its antioxidant abilities may be used to help assist in preventing or treating a number

    Mixtures: O-Cal Prenatal Vitamin, O-Cal FA multivitaminCategories: Compounds used in a research, industrial, or household setting, Vitamin E