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Displaying results 191 - 200 of 5912 in total
  1. Drug

    Ethchlorvynol

    go.drugbank.com/drugs/DB00189
    ApprovedIllicitWithdrawn

    It has been used to treat insomnia, but has been largely superseded and is only offered where an intolerance or allergy to other drugs exists.

  2. Drug

    Bismuth subsalicylate

    go.drugbank.com/drugs/DB01294
    ApprovedVet approved

    Exhibiting antibacterial and gastroprotective properties, bismuth subsalicylate is an insoluble salt of [salicylic acid] linked to trivalent [bismuth cation]. … [A230728, A230773] Bismuth subsalicylate was first approved by the FDA in 1939 and is now mainly used to relieve nausea, diarrhea, and gastrointestinal discomfort.

    Mixtures: Pepto-Bismol and Pepto-Bismol To Go, Pepto-Bismol and Pepto-Bismol To GoSynonyms: 2-Hydroxy-benzo[1,3,2]dioxabismin-4-one
  3. Drug

    Margetuximab

    go.drugbank.com/drugs/DB14967
    ApprovedInvestigational

    However, due to its modified Fc region, margetuximab binds with higher affinity to both CD16A variants and exhibits weaker binding to the inhibitory CD32B Fc receptor, resulting in more efficient antibody-dependent … cell-mediated cytotoxicity (ADCC) and increased efficacy compared to [trastuzumab].

  4. Target

    F-box/WD repeat-containing protein 1A

    go.drugbank.com/bio_entities/BE0021224
    TargetHumans

    Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (PubMed:10066435, PubMed:10497169, PubMed:...

    Polypeptides: F-box/WD repeat-containing protein 1A
  5. Drug

    Mogamulizumab

    go.drugbank.com/drugs/DB12498
    ApprovedInvestigational

    approved mogamulizumab injection (also known as _Poteligeo_) for intravenous use for the treatment of adult patients with relapsed or refractory mycosis fungoides (MF) or Sézary syndrome (SS) after at least one

  6. Drug

    Benzyl benzoate

    go.drugbank.com/drugs/DB00676
    Approved

    Benzyl benzoate is one of the older preparations used to treat scabies. Scabies is a skin infection caused by the mite sarcoptes scabiei. … It is characterised by severe itching (particularly at night), red spots, and may lead to a secondary infection. Benzyl benzoate is lethal to this mite and so is useful in the treatment of scabies.

    International brands: BE BOProducts: BENZYL BENZOATE APPLICATION BP 25% w/v
  7. Drug

    Urea

    go.drugbank.com/drugs/DB03904
    ApprovedInvestigational

    It is the principal end product of protein catabolism and constitutes about one half of the total urinary solids.

    Mixtures: Thomas Formula No 17, Thomas Formula No 47Products: URECARE CREAM 10% w/w, AXCEL UREA CREAM 10% w/w
  8. Drug

    Serine

    go.drugbank.com/drugs/DB00133
    ApprovedInvestigationalNutraceutical

    A non-essential amino acid occurring in natural form as the L-isomer. It is synthesized from glycine or threonine. It is involved in the biosynthesis of purines; pyrimidines; and other amino acids.

    Mixtures: Nutriflex Lipid special ohne Elektrolyte Emulsion zur Infusion, Nutriflex Omega special ohne Elektrolyte B. Braun Emulsion zur Infusion
  9. Drug

    Pixantrone

    go.drugbank.com/drugs/DB06193
    ApprovedWithdrawn

    Patients refractory to treatment, or those who relapse, are discouraged from further anthracycline use due to cumulative cardiotoxicity. … Pixantrone was designed to treat relapsed or refractory aggressive non-Hodgkin's lymphoma(NHL) in patients who have failed two prior lines of therapy. [2] For patients suffering from NHL, first line therapies

  10. Drug

    Guaifenesin

    go.drugbank.com/drugs/DB00874
    ApprovedInvestigationalVet approved

    Guaifenesin possesses a storied history, having been originally formally approved by the US FDA in 1952 and continues to be one of very few - if not perhaps the only drug that is readily available and … to be safe and effective in children under the age of 6 years [F4525].

    Mixtures: M-clear Wc, Virtussin Ac W/alc