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Displaying results 191 - 200 of 10000 in total
  1. Drug

    Almotriptan

    go.drugbank.com/drugs/DB00918
    Approved

    Almotriptan is in a class of medications called selective serotonin receptor agonists. … It works by narrowing blood vessels in the brain, stopping pain signals from being sent to the brain, and stopping the release of certain natural substances that cause pain, nausea, and other symptoms

    Products: PMS-almotriptan, ALMOTRIPTAN EG
  2. Drug

    Acetylsalicylic acid

    go.drugbank.com/drugs/DB00945
    ApprovedInvestigationalVet approved

    Aspirin is classified as a _non-selective cyclooxygenase (COX) inhibitor_ [A32682, A177268] and is available in many doses and forms, including chewable tablets, suppositories, extended release formulations … Acetylsalicylic acid has both anti-inflammatory and antipyretic effects.

    Mixtures: Pravigard Pac, Pravigard PacProducts: Ag-asa Chew, Jamp-asa Chew
  3. Drug

    CHIR-124

    go.drugbank.com/drugs/DB06852
    Experimental

    CHIR-124 is a potent inhibitor of Chk1 that potentiates the cytotoxicity of topoisomerase I poisons in vitro and in vivo.

  4. Drug

    Vincristine

    go.drugbank.com/drugs/DB00541
    ApprovedInvestigational

    Vincristine is an antitumor vinca alkaloid isolated from Vinca Rosea. … It is marketed under several brand names, many of which have different formulations such as Marqibo (liposomal injection) and Vincasar.

    Products: Vincasar PFS, VINCRISTINA EG
  5. Drug

    Tobramycin

    go.drugbank.com/drugs/DB00684
    ApprovedInvestigational

    [L32744, L32749] Its use is limited in some cases by characteristic toxicities such as nephrotoxicity and ototoxicity, yet it remains a valuable option in the face of growing resistance to front-line antibiotics … [A232294] Inhaled tobramycin is notable for its use in treating chronic _Pseudomonas aeruginosa_ infections in cystic fibrosis patients, as _P. aeruginosa_ is notoriously inherently resistant to many antibiotics

    Mixtures: TOBRAMICINA E DESAMETASONE EG, TOBRAMICINA E DESAMETASONE DOC GENERICIProducts: Kitabis Pak, Tobramycin Inhalation Solution Pak
  6. Drug

    Trabectedin

    go.drugbank.com/drugs/DB05109
    ApprovedInvestigational

    Food and Drug Administration (FDA) have approved trabectedin as an orphan drug in soft tissue sarcomas and ovarian cancer. … Trabectedin, also referred as ET-743 during its development, is a marine-derived antitumor agent discovered in the Carribean tunicate _Ecteinascidia turbinata_ and now produced synthetically.

    Products: TRABECTEDINA EG, Trabectedin TEVA 0,25 mg Pulver für ein Konzentrat zur Herstellung einer Infusionslösung
  7. Drug

    Guaifenesin

    go.drugbank.com/drugs/DB00874
    ApprovedInvestigationalVet approved

    used as an expectorant [F4525]. … as an NMDA receptor antagonist [A177652].

    Mixtures: Entex PAC, N-ACETILCISTEÍNA MAS GUAYACOLATO DE GLICERILOProducts: Siltussin DAS, Diabetic Siltussin DAS-Na
  8. Drug

    Galantamine

    go.drugbank.com/drugs/DB00674
    ApprovedInvestigational

    [A1018] First characterized in the early 1950s, galantamine is a tertiary alkaloid that was extracted from botanical sources, such as _Galanthus nivalis_. … [A201968] Galantamine was first studied in paralytic and neuropathic conditions, such as myopathies and postpolio paralytic conditions, and for reversal of neuromuscular blockade.

    Products: PMS-galantamine ER, PMS-galantamine
  9. Drug

    Quinapril

    go.drugbank.com/drugs/DB00881
    ApprovedInvestigational

    [L8420,L8423] ACE inhibitors are commonly used as a first line therapy in the treatment of hypertension, along with thiazide diuretics or beta blockers. … [A184844] Quinapril was granted FDA approval on 19 November 1991.[L8420] A combination tablet with [hydrochlorothiazide] was also approved on 28 December 1999.[L8423]

    Mixtures: QUINAPRIL IDROCLOROTIAZIDE EG, QUINAPRIL IDROCLOROTIAZIDE EGCategories: Agents Acting on the Renin-Angiotensin System
  10. Drug

    Bupropion

    go.drugbank.com/drugs/DB01156
    ApprovedInvestigational

    [A178816] Bupropion is sometimes used as an add-on agent to first-line treatments of depression such as selective serotonin reuptake inhibitor (SSRI) medications when there is a treatment-failure or … While it has comparable effectiveness to typical first-line options for the treatment of depression such as SSRIs,[A178798,A178804] bupropion is a unique option for the treatment of MDD as it lacks any

    Products: PMS-bupropion SR, Aplenzin ER