Search

Displaying results 191 - 200 of 536 in total
  1. Target

    KAT8 regulatory NSL complex subunit 3

    go.drugbank.com/bio_entities/BE0009091
    TargetHumans

    Non-catalytic component of the NSL histone acetyltransferase complex, a multiprotein complex that mediates histone H4 acetylation at 'Lys-5'- and 'Lys-8' (H4K5ac and H4K8ac) at transcription start sites … The NSL complex also acts as a regulator of gene expression in mitochondria (PubMed:27768893).

    Polypeptides: KAT8 regulatory NSL complex subunit 3Synonyms: NSL complex protein NSL3
  2. Indication

    Uncomplicated Urinary Tract Infections caused by Citrobacter freundii complex

    go.drugbank.com/conditions/DBCOND0173161
    Drugs: Gepotidacin
    Synonyms: Uncomplicated Urinary Tract Infections caused by Citrobacter freundii complex
  3. Drug

    Pixantrone

    go.drugbank.com/drugs/DB06193
    ApprovedWithdrawn

    It will compare pixantrone efficacy to that of gemcitabine. [2]

  4. Target

    Cytochrome b-c1 complex subunit 8

    go.drugbank.com/bio_entities/BE0003857
    TargetHumans

    The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase … Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation.

    Polypeptides: Cytochrome b-c1 complex subunit 8Synonyms: Complex III subunit 8, Complex III subunit VIII
  5. Target

    Cytochrome b-c1 complex subunit 9

    go.drugbank.com/bio_entities/BE0003861
    TargetHumans

    The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase … Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation.

    Polypeptides: Cytochrome b-c1 complex subunit 9Synonyms: Complex III subunit 9, Complex III subunit X
  6. Target

    Cytochrome b6-f complex subunit 5

    go.drugbank.com/bio_entities/BE0003906
    TargetMastigocladus laminosus

    PetG is required for either the stability or assembly of the cytochrome b6-f complex. … Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.

    Polypeptides: Cytochrome b6-f complex subunit 5Synonyms: Cytochrome b6-f complex subunit V, Cytochrome b6-f complex subunit PetG
  7. Target

    Fatty acid oxidation complex subunit alpha

    go.drugbank.com/bio_entities/BE0004256
    TargetPseudomonas fragi

    Involved in the aerobic and anaerobic degradation of long-chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-Co...

    Polypeptides: Fatty acid oxidation complex subunit alpha
  8. Target

    Trafficking protein particle complex subunit 4

    go.drugbank.com/bio_entities/BE0004278
    TargetHumans

    Core component of the TRAPP complexes which has a function of guanine nucleotide exchange factor activity for Rab1 GTPase (Probable).

    Polypeptides: Trafficking protein particle complex subunit 4
  9. Target

    Trafficking protein particle complex subunit 1

    go.drugbank.com/bio_entities/BE0004279
    TargetHumans

    May play a role in vesicular transport from endoplasmic reticulum to Golgi

    Polypeptides: Trafficking protein particle complex subunit 1
  10. Target

    T-complex protein 1 subunit gamma

    go.drugbank.com/bio_entities/BE0004554
    TargetHumans

    As part of the TRiC complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia (PubMed:20080638) … Component of the chaperonin-containing T-complex (TRiC), a molecular chaperone complex that assists the folding of actin, tubulin and other proteins upon ATP hydrolysis (PubMed:25467444, PubMed:36493755

    Polypeptides: T-complex protein 1 subunit gammaSynonyms: Chaperonin containing T-complex polypeptide 1 subunit 3