Search

Displaying results 191 - 200 of 10000 in total
  1. Pathway

    Tramadol Metabolism Pathway

    smpdb.ca/view/SMP0000637
    Drug metabolism

    Tramadol (also named Ultram) is a class of opioid pain medication that used for treating pain. Metabolism of tramadol mainly happened in liver cell. … The O-demethylation of tramadol is catalyzed by the cytochrome CYP2D6 to form O-Desmethyltramadol, which further metabolized to O-Desmethyltramadol glucuronide through UDP-glucuronosyltransferase 2B7 and

    Drugs: NADH · ATP · Tramadol · Mesoheme · Uridine-5'-Diphosphate · Formaldehyde
  2. Drug

    IMT504

    go.drugbank.com/drugs/DB17792
    Investigational

    IMT504, a non-CpG 24-mer oligodeoxynucleotide, is an immunomodulatory oligonucleotide currently being investigated as a rabies vaccine.[A259467]

    Synonyms: PyNTTTTGT class of oligodeoxynucleotide with a 24-base single chain composed of nucleotide sequence 5'TCATCATTTTGTCATTTTGTCATT 3', DNA, D(P-THIO)(T-C-A-T-C-A-T-T-T-T-G-T-C-A-T-T-T-T-G-T-C-A-T-T)
  3. Drug

    Estradiol

    go.drugbank.com/drugs/DB00783
    ApprovedInvestigationalVet approved

    Because it has a low oral bioavailability on its own, estradiol is commonly formulated with an ester side-chain. … [DB00977] (EE) is a synthetic form of estradiol commonly used as the estrogenic component of most combination oral contraceptive pills (OCPs).

    Synonyms: (17β)-estra-1,3,5(10)-triene-3,17-diol, 17β-estra-1,3,5(10)-triene-3,17-diolInternational brands: Estraderm MX
  4. Drug

    AKV-9

    go.drugbank.com/drugs/DB18061
    Experimental

    Synonyms: 5-((S)-1-(3,5-bis(trifluoromethyl)phenoxy)ethyl)-3-hydroxycyclohex-2-en-1-one, 1,3-Cyclohexanedione, 5-[(1S)-1-[3,5-bis(trifluoromethyl)phenoxy]ethyl]-
  5. Drug

    Fluticasone propionate

    go.drugbank.com/drugs/DB00588
    ApprovedInvestigational

    Fluticasone propionate was first approved in 1990[L5962].

    Mixtures: SALFLUTIN 50/100UG 60 ED, SALFLUTIN 50/250UG 60 EDCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Inhibitors
  6. Drug

    Salvia miltiorrhiza root

    go.drugbank.com/drugs/DB14337
    Investigational

    Salvia miltiorrhiza root is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.

    Synonyms: Salviae Miltiorrhizae Radix Et RhizomaCategories: Herbs and Natural Products, Herbs (Hypotensive Properties)
  7. Drug

    Dextrose, unspecified form

    go.drugbank.com/drugs/DB09341
    ApprovedInvestigationalVet approved

    It is primarily stored as starch in plants and glycogen in animals to be used in various metabolic processes in the cellular level. … It is produced in humans via hepatic gluconeogenesis and breakdown of polymeric glucose forms (glycogenolysis).

    Mixtures: SODIO60 MCG +POTASIO 20 MCG + CLORURO 50 MCG + CITRATO 30 MG + GLUCOSA111 MCG, CLORURO DE POTASIO 20 mEq EN DEXTROSA AL 5% Y CLORURO DE SODIO AL 0.45% BAXTERCategories: Compounds used in a research, industrial, or household setting
  8. Drug

    Larsucosterol

    go.drugbank.com/drugs/DB18079
    Investigational

    Synonyms: 25-hydroxycholest-5-en-3.beta.-yl hydrogen sulfate, Cholest-5-ene-3,25-diol, 3-(hydrogen sulfate), (3.beta.)-
  9. Drug

    Zetomipzomib

    go.drugbank.com/drugs/DB16070
    Investigational

    Zetomipzomib is under investigation in clinical trial NCT04033926 (A Phase 2 Study of KZR-616 to Evaluate Safety and Efficacy in Patients With Active Polymyositis or Dermatomyositis).

    Synonyms: (2S,3R)-N-[(2S)-3-(cyclopent-1-en-1-yl)-1-[(2R)-2-methyloxiran-2-yl]-1-oxopropan-2-yl]-3-hydroxy-3-(4-methoxyphenyl)-2-[(2S)-2-[2-(morpholin-4-yl)acetamido]propanamido]propanamide
  10. Drug

    Panax notoginseng root

    go.drugbank.com/drugs/DB14304
    Investigational

    Panax notoginseng root is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.

    Synonyms: Notoginseng Radix Et Rhizoma