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Meclizine
go.drugbank.com/drugs/DB00737ApprovedInvestigationalMeclizine is a histamine H1 antagonist with antiemetic and antivertigo properties. … [L6760] Commonly marketed under the brand name Antivert in the U.S., meclizine is available as oral tablets.
Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 1-RingProducts: Trav-L-tabs, Dramamine - NRiluzole
go.drugbank.com/drugs/DB00740ApprovedInvestigationalRiluzole is marketed as Rilutek by Sanofi. … A glutamate antagonist (receptors, glutamate) used as an anticonvulsant (anticonvulsants) and to prolong the survival of patients with amyotrophic lateral sclerosis.
Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 1-RingProducts: RILUTEK® TABLETAS X 50MG, TEGLUTIK® SUSPENSIÓN ORAL 5 MG/MLPrilocaine
go.drugbank.com/drugs/DB00750ApprovedInvestigationalA local anesthetic that is similar pharmacologically to lidocaine. Currently, it is used most often for infiltration anesthesia in dentistry. (From AMA Drug Evaluations Annual, 1992, p165)
Mixtures: LİDORİN %5+%5 KREM, 1 ADET 5 G, LİDORİN %5+%5 KREM, 5 ADET 5 GSynonyms: N-(2-Methylphenyl)-2-(propylamino)propanamide, 2-(Propylamino)-o-propionotoluidideEpinastine
go.drugbank.com/drugs/DB00751ApprovedIt has a multi-action effect that inhibits the allergic response in 3 ways: 1. stabilizes mast cells by preventing mast cell degranulation to control the allergic response, 2. prevents histamine binding … Epinastine is used for the prevention of itching associated with allergic conjunctivitis.
Mixtures: FLURINOL(R) D COMPRIMIDOS DE LIBERACION MODIFICADACategories: Cytochrome P-450 Substrates, P-glycoprotein substratesTranylcypromine
go.drugbank.com/drugs/DB00752ApprovedInvestigationalTranylcypromine is a racemate comprising equal amounts of (1R,2S)- and (1S,2R)-2-phenylcyclopropan-1-amine with the chiral centers both located on the cylopropane ring. … An irreversible monoamine oxidase inhibitor that is used as an antidepressant (INN tranylcypromine).
Categories: Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates, Cytochrome P-450 CYP1A2 InhibitorsSynonyms: (1R*,2S*)-2-phenylcyclopropan-1-amine, (±)-trans-2-phenylcyclopropylamineIsoflurane
go.drugbank.com/drugs/DB00753ApprovedInvestigationalVet approvedA stable, non-explosive inhalation anesthetic, relatively free from significant side effects.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2B6 InducersSynonyms: 1-chloro-2,2,2-trifluoroethyl difluoromethyl etherClopidogrel
go.drugbank.com/drugs/DB00758ApprovedInvestigational[A180508,L7213] Clopidogrel is indicated to reduce the risk of myocardial infarction for patients with non-ST elevated acute coronary syndrome (ACS), patients with ST-elevated myocardial infarction, and … Clopidogrel is a prodrug of a platelet inhibitor used to reduce the risk of myocardial infarction and stroke.
Mixtures: ATELIT-DUO® 75/100 MG TABLETAS, KLOGEL-A 75/75 MG KAPSUL, 30 ADETCategories: P-glycoprotein substrates, Cytochrome P-450 SubstratesBenzquinamide
go.drugbank.com/drugs/DB00767ApprovedWithdrawnBenzquinamide is a discontinued antiemetic compound with antihistaminic, mild anticholinergic, and sedative properties. … The mechanism of action is not known, but presumably benzquinamide works via antagonism of muscarinic acetycholine receptors and histamine H1 receptors.
Categories: P-glycoprotein inhibitors, Heterocyclic Compounds, 2-RingAlprostadil
go.drugbank.com/drugs/DB00770ApprovedInvestigationalAlprostadil is a chemically-identical synthetic form of prostaglandin E1 (PGE1), a potent vasodilator produced endogenously. … for whom oral treatment is either contraindicated or ineffective.
Categories: Prostaglandins ESynonyms: PGE-1, (11α,13E,15S)-11,15-dihydroxy-9-oxoprost-13-en-1-oic acidTirofiban
go.drugbank.com/drugs/DB00775ApprovedInvestigationalTirofiban prevents the blood from clotting during episodes of chest pain or a heart attack, or while the patient is undergoing a procedure to treat a blocked coronary artery. … It is a non-peptide reversible antagonist of the platelet glycoprotein (GP) IIb/IIIa receptor, and inhibits platelet aggregation.
Synonyms: (2S)-2-(butylsulfonylamino)-3-[4-(4-piperidin-4-ylbutoxy)phenyl]propanoic acid, N-(Butylsulfonyl)-O-(4-(4-piperidyl)butyl)-L-tyrosineProducts: INFÜZYON IÇIN KONSANTRE ÇÖZELTI IÇEREN FLAKON ,1 ADET, TIROSTU 12.5 MG/50 ML IV KONSANTRE İNFÜZYONLUK ÇÖZELTİ, 1 ADET