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Medium-chain triglycerides
go.drugbank.com/drugs/DB13959ApprovedInvestigationalMedium-chain triglycerides (MCTs) are triglycerides made up of a glycerol backbone and three fatty acids with an aliphatic tail of six to 12 carbon atoms. … [A246688] MCTs are used in parenteral nutrition therapy: they serve as a source of calories and essential fatty acids in conditions associated with malnutrition and malabsorption.[L41340]
Soybean oil
go.drugbank.com/drugs/DB09422ApprovedInvestigationalDerived from soybeans, soybean oil is a common vegetable oil and a source of polyunsaturated and saturated fatty acids. … It is used as a cooking oil and lipid emulsion for parenteral nutrition in clinical settings. Soybean oil-based lipid emulsion is the only FDA-approved lipid formulation for clinical use.
Oteseconazole
go.drugbank.com/drugs/DB13055ApprovedInvestigational[L41635] CYP51, also known as 14α demethylase, participates in the formation of ergosterol, a compound that plays a vital role in the integrity of cell membranes. … Oteseconazole is an azole metalloenzyme inhibitor that targets fungal CYP51.
Digoxin
go.drugbank.com/drugs/DB00390ApprovedInvestigational[A178234] Digoxin is classified as a cardiac glycoside and was initially approved by the FDA in 1954. … They were one of the first to prescribe cardiac glycosides, according to ancient literature dating as early as the 1250s.[A178240]
Categories: BSEP/ABCB11 Substrates with a Narrow Therapeutic Index, P-glycoprotein substrates with a Narrow Therapeutic IndexEstradiol
go.drugbank.com/drugs/DB00783ApprovedInvestigationalVet approvedBecause it has a low oral bioavailability on its own, estradiol is commonly formulated with an ester side-chain. … [L11485,L11488,L11491, L11494,L11497,L11500,L11503] When used for oral or IM administration, estradiol is commonly synthesized as a pro-drug ester (such as [DB13952], [DB13953], [DB13954], [DB13955
Pramocaine
go.drugbank.com/drugs/DB09345ApprovedPramocaine (also known as pramoxine or pramoxine HCI) is a topical anesthetic and antipruritic.
Mixtures: MEDICATED ANTI-ITCH Well at WalgreensThiamine
go.drugbank.com/drugs/DB00152ApprovedInvestigationalNutraceuticalVet approvedThiamine or thiamin, also known as vitamin B1, is a colorless compound with the chemical formula C12H17N4OS. It is soluble in water and insoluble in alcohol. Thiamine decomposes if heated. … Thiamine plays an important role in helping the body convert carbohydrates and fat into energy.
Mixtures: Vinate AZ, Am CapsPemirolast
go.drugbank.com/drugs/DB00885ApprovedWithdrawnPemirolast potassium is a slightly yellow powder that is soluble in water. It is a mast cell stabilizer that acts as an antiallergic agent. … As an ophthalmic aqueous sterile solution, pemirolast is used for the prevention of itching of the eyes caused by allergies such as hay fever, and allergic conjunctivitis.
Rifamycin
go.drugbank.com/drugs/DB11753ApprovedInvestigationalWithdrawnProduct which allowed it to have a status a priority review. … The parent compound of rifamycin was rifamycin B which was originally obtained as a main product in the presence of diethylbarburitic acid.