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Displaying results 2051 - 2060 of 10000 in total
  1. Pathway

    Pyruvate Dehydrogenase Complex Deficiency

    smpdb.ca/view/SMP0125772
    Disease

    PDHA1 encodes the pyruvate dehydrogenase complex (PDC) a critical complex that converts pyruvate from glycolysis to acetyl CoA for the citric acid cycle. … Pyruvate dehydrogenase complex deficiency results from a mutation in the E1-alpha polypeptide gene (PDHA1).

    Drugs: Pyruvic acid · Biotin · Adenosine phosphate · Glutathione · NADH · ATP +13 more
    Enzymes: Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial
  2. Drug

    Xanomeline

    go.drugbank.com/drugs/DB15357
    ApprovedInvestigational

    discovered that M1 and M4 muscarinic acetylcholine receptors are highly expressed in brain regions that are implicated in cognition. … [A264509] Advances in pre-clinical research and findings in clinical trials have led to a resurgence of interest in the cognition-enhancing potential of muscarinic agonists in schizophrenia, as it was

  3. Drug

    Indium In-111 chloride

    go.drugbank.com/drugs/DB09490
    Approved

    It is supplied as a sterile, pyrogen-free solution of Indium ("'In) Chloride in O.04M HCI. … and for radiolabeling Zevalin (ibritumomab tiuxetan) in preparations used for radioimmunotherapy procedures.

    Mixtures: INDIO (111-IN) OSSINA CURIUM NETHERLANDS, Kit for the Preparation of Indium In 111 PentetreotideSynonyms: Indium chloride In-111, Indium In 111 chloride
  4. Drug

    Anthoxanthum odoratum

    go.drugbank.com/drugs/DB14163
    Approved

    Anthoxanthum odoratum allergenic extract is used in allergenic testing.

    Mixtures: ORALAIR 100 IR + 300 IR Sublingualtabletten, ORALAIR 100 IR + 300 IR SublingualtablettenProducts: Standardized Grass Pollen - Sweet Vernal Grass (10,000 Bau/ml)
  5. Drug

    Fructose

    go.drugbank.com/drugs/DB04173
    ApprovedInvestigational

    Mixtures: Formula EmCategories: Compounds used in a research, industrial, or household setting
  6. Target

    tRNA-dihydrouridine(20a/20b) synthase [NAD(P)+]-like

    go.drugbank.com/bio_entities/BE0022092
    EnzymeHumans

    Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs

    Polypeptides: tRNA-dihydrouridine(20a/20b) synthase [NAD(P)+]-like
  7. Drug

    Aclidinium

    go.drugbank.com/drugs/DB08897
    Approved

    FDA approved on July 24, 2012. … Aclidinium is an anticholinergic for the long-term management of chronic obstructive pulmonary disease (COPD).

    Mixtures: Duaklir Genuair 340/12 mcg Inhalation PowderProducts: EKLIRA®GENUAIR® 322 MCG/DOSIS, Eklira Genuair 322 mcg Inhalation Powder
  8. Drug

    Edrophonium

    go.drugbank.com/drugs/DB01010
    Approved

    A rapid-onset, short-acting cholinesterase inhibitor used in cardiac arrhythmias and in the diagnosis of myasthenia gravis. It has also been used as an antidote to curare principles.

    Categories: Compounds used in a research, industrial, or household settingSynonyms: 3-hydroxy-N,N-dimethyl-N-ethylanilinium, N-ethyl-3-hydroxy-N,N-dimethylanilinium
  9. Drug

    Potassium nitrate

    go.drugbank.com/drugs/DB11090
    ApprovedInvestigational

    In addition, potassium nitrate is used as a diuretic in pigs, cattle, and horses. It is administered orally doses up to 30 g per animal per day [L1736]. … Potassium nitrate is a common active ingredient in toothpaste, exerting an anti-sensitivity action.

    Mixtures: SENSORAL 250 ML SOLUSYON, Kiss My Face Enamel ExtraCategories: Compounds used in a research, industrial, or household setting
  10. Drug

    Testosterone propionate

    go.drugbank.com/drugs/DB01420
    ApprovedInvestigationalVet approvedWithdrawn

    Currently, this drug has been discontinued in humans, but the vet application is still available as an OTC.[L1160] … It is a synthetic androstane steroid derivative of testosterone in the form of 17β propionate ester of testosterone.

    Mixtures: TEST - COMP 250, SUSTANON 250 INJECTIONProducts: Malogen In Oil Liq 100mg/ml, Testosterone Propionate Inj 100mg/ml