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Displaying results 2081 - 2090 of 10000 in total
  1. Drug

    Chymotrypsin

    go.drugbank.com/drugs/DB09375
    ApprovedInvestigationalVet approvedWithdrawn

    Chymotrypsin is the most abundant pancreatic proteases that represent up to 10-20% of the total protein synthesized by the exocrine pancreas [A32637]. … Like most proteolytic enzymes, chymotrypsin is activated from its inactive zymogen precursor, chymotrypsinogen, in presence of [DB11237].

    Categories: Enzymes and Coenzymes, Blood and Blood Forming Organs
  2. Indication

    Venous Embolism

    go.drugbank.com/conditions/DBCOND0133256
    Drugs: Phenprocoumon
    Synonyms: Acute embolism and thrombosis of unspecified vein
  3. Indication

    Alcohol Problem Drinking

    go.drugbank.com/conditions/DBCOND0132393
    Drugs: Disulfiram
    Synonyms: [X]Mental and behavioral disorders due to use of alcohol: dependence syndrome, [X]Mental and behavioural disorders due to use of alcohol: dependence syndrome
  4. Indication

    Colon Polyps

    go.drugbank.com/conditions/DBCOND0032674
    Drugs: Acetylsalicylic acid · Sulindac
    Synonyms: Anal and rectal polyp, Anal and rectal polyp (disorder)
  5. Drug

    Potassium alum

    go.drugbank.com/drugs/DB09087
    ApprovedWithdrawn

    [L1070] It is an inorganic salt, also called potassium aluminum sulfate with a formula of AlK(SO4)2 that is predominantly produced in the dodecahydrate form (AlK(SO4)2 * 12H2O). … Potassium alum is considered by the FDA as a generally recognized as safe (GRAS) substance.

    Mixtures: Gingibraid W Epineph and Alum 1e, Gingibraid W Epineph and Alum 2e
  6. Indication

    Insomnia

    go.drugbank.com/conditions/DBCOND0017531
    Drugs: Amitriptyline · Brotizolam · Butabarbital · Cinolazepam · Clotiazepam · Daridorexant +31 more
    Synonyms: Disorders of initiating and maintaining sleep, Disorders of initiating and maintaining sleep (disorder)
  7. Drug

    Sacubitril

    go.drugbank.com/drugs/DB09292
    ApprovedInvestigational

    It was approved by the FDA after being given the status of priority review for on July 7, 2015. … ANP and BNP are released under atrial and ventricle stress, which activate downstream receptors leading to vasodilation, natriuresis and diuresis.

    Mixtures: ENTRESTO FILM COATED TABLET 100MG, Uperio 100mg Film-coated TabletsCategories: valsartan and sacubitril, Amino Acids, Peptides, and Proteins
  8. Drug

    Bezlotoxumab

    go.drugbank.com/drugs/DB13140
    Approved

    Bezlotoxumab is a fully humanized ImmunoglobulinG1 (IgG1) kappa monoclonal antibody that binds to _Clostridium difficile_ toxin B and neutralizes its effects. … [A260106] The drug was granted full approval by the EMA on January 18, 2017.[L47191]

    Categories: Amino Acids, Peptides, and Proteins, Immune Sera and Immunoglobulins
  9. Drug

    Bromfenac

    go.drugbank.com/drugs/DB00963
    ApprovedWithdrawn

    Non-ophthalmic formulations of bromfenac were withdrawn in the US in 1998 due to cases of severe liver toxicity.[L43942,T239] … Their well-characterized anti-inflammatory activity, analgesic property, and established safety record have also made NSAIDs an important tool for optimizing surgical outcomes.

    Mixtures: Pred-Brom, Pred-Brom
  10. Drug

    Rolapitant

    go.drugbank.com/drugs/DB09291
    ApprovedInvestigational

    By blocking Substance P from interacting with NK-1 receptors in the gut and the central nervous system, rolapitant prevents late-phase CINV. … Unlike other available NK-1 receptor antagonists, rolapitant is not an inhibitor of Cytochrome P450 enzyme CYP3A4 and has a long elimination half-life, allowing a single dose to prevent both acute and

    Categories: Antiemetics and Antinauseants, Alimentary Tract and Metabolism