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Nonoxynol-9
go.drugbank.com/drugs/DB06804ApprovedWithdrawnNonoxynol-9 (N-9) is a typical surfactant used as a vaginal spermicide. Spermicides are locally acting non-hormonal contraceptives. … N-9 has been in use for more than 30 years as an over-the-counter (OTC) drug in creams, gels, foams and condom lubricants.
Categories: Compounds used in a research, industrial, or household settingSynonyms: Nonoxynol 9, Nonoxynol-9Ajmaline
go.drugbank.com/drugs/DB01426ApprovedWithdrawnIt is a class Ia antiarrhythmic agent that apparently acts by changing the shape and threshold of cardiac action potentials. … Ajmaline produces potent sodium channel blocking effects and a very short half-life which makes it a very useful drug for acute intravenous treatments.
Synonyms: (5aR,6S,8S,10S,11S,11aS,12aR,13R)-5-methyl-5a,6,8,9,10,11,11a,12-octahydro-5H-6,10:11,12a-dimethanoindolo[3,2-b]quinolizine-8,13-diolCategories: Antiarrhythmics, Class Ia, Antiarrhythmics, Class IRomiplostim
go.drugbank.com/drugs/DB05332ApprovedInvestigationalEach subunit consists of an IgG1 Fc carrier domain that is covalently attached to a polypeptide sequence that contains two binding domains to interact with thrombopoietin receptor c-Mpl. … Romiplostim is produced by recombinant DNA technology in Escherichia coli. FDA approved on August 22, 2008.
Products: NPLATE ® 500 MCG, NPLATE 500 MCG ENJEKSİYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN TOZ, 1 ADETSelenium Sulfide
go.drugbank.com/drugs/DB00971ApprovedSelenium Sulfide is an antifungal agent as well as a cytostatic agent, slowing the growth of hyperproliferative cells in seborrhea. … Selenium Sulfide is the active ingredient often used in shampoos for the treatment of dandruff, seborrheic dermatitis and tinea capitis, a fungal infection that is primarily a disease of preadolescent
Products: SESUL SÜSPANSİYON, 120 ML, Selsun Azul Suave y Manejable HumectantePegcetacoplan
go.drugbank.com/drugs/DB16694ApprovedInvestigationalPegcetacoplan is a complement inhibitor indicated in the treatment of paroxysmal nocturnal hemoglobinuria (PNH). … [A235000,A235005] Pegcetacoplan was developed out of a need for an inhibitor of complement mediated hemolysis further upstream of C5.
Products: EMPAVELI® 54 MG/ML SOLUCIÓN INYECTABLESimeprevir
go.drugbank.com/drugs/DB06290ApprovedWithdrawnInhibiting HCV NS3/4A protease in a potent and highly specific manner, simeprevir is a direct-acting antiviral agent against the hepatitis C virus. … Like all NS3/4A inhibitors, simeprevir is a serine protease inhibitor in similarity to [DB08873] and [DB05521] but is classified as a second generation protease inhibitor.
Categories: NS3/4A Protease Inhibitors, HCV NS3/4A Protease InhibitorsProducts: OLYSIO 150 MG KAPSUL ,KAPSUL, 28 ADETZopiclone
go.drugbank.com/drugs/DB01198ApprovedInvestigationalZopiclone is a novel hypnotic agent used in the treatment of insomnia. Its mechanism of action is based on modulating benzodiazepine receptors.
Synonyms: 6-(5-Chloro-2-pyridinyl)-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazin-5-yl 4-methyl-1-piperazinecarboxylateCategories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 1-RingConjugated estrogens
go.drugbank.com/drugs/DB00286ApprovedInvestigationalIt also presents a large number of unidentified molecules with weak estrogenic activity as well as non-human molecules when it is obtained from pregnant mares urine. … Both of these products are later conjugated to natrium sulfate by ester bonds in order to make them more water soluble.
Mixtures: DUAVIVE 20 mg/0.45 mg modified - release tablets, DUAVİVE 0.45 MG/20 MG DEĞİŞTİRİLMİŞ SALIMLI TABLET, 30 TABLETCategories: Cytochrome P-450 Substrates, P-glycoprotein substratesSulfasalazine
go.drugbank.com/drugs/DB00795ApprovedInvestigationalIt is indicated for managing inflammatory diseases such as ulcerative colitis and rheumatoid arthritis (RA). … [A255582] Compared to the first line treatment of RA like methotrexate, sulfasalazine is almost as efficacious as methotrexate although with slightly less tolerability.
Categories: Non COX-2 selective NSAIDSSynonyms: 柳氮磺吡啶, 2-Hydroxy-5-((4-((2-pyridinylamino)sulfonyl)phenyl)azo)benzoic acidAsenapine
go.drugbank.com/drugs/DB06216ApprovedInvestigationalDeveloped by Schering-Plough after its merger with Organon International, asenapine is a sublingually administered, atypical antipsychotic for treatment of schizophrenia and acute mania associated with … It is also for severe post-traumatic stress disorder nightmares in soldiers as an off-label use. FDA approved on August 13, 2009.
Categories: Cytochrome P-450 Substrates, Adrenergic alpha-1 Receptor AntagonistsProducts: SYCREST 5MG DILALTI TABLET, 100 TABLET, SYCREST 10MG DILALTI TABLET, 100 TABLET