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Displaying results 201 - 210 of 661 in total
  1. Target

    Target of rapamycin complex 2 subunit MAPKAP1

    go.drugbank.com/bio_entities/BE0018900
    TargetHumans

    Inhibits HRAS and KRAS independently of mTORC2 complex (PubMed:17303383, PubMed:34380736, PubMed:35522713). … Involved in ciliogenesis, regulates cilia length through its interaction with CCDC28B independently of mTORC2 complex (PubMed:23727834)

    Polypeptides: Target of rapamycin complex 2 subunit MAPKAP1
  2. Target

    Integrase, catalytic core

    go.drugbank.com/bio_entities/BE0003386
    TargetNitrosomonas europaea (strain ATCC 19718 / NBRC 14298)

    Polypeptides: Integrase, catalytic core
  3. Target

    Neurocan core protein

    go.drugbank.com/bio_entities/BE0004512
    TargetHumans

    May modulate neuronal adhesion and neurite growth during development by binding to neural cell adhesion molecules (NG-CAM and N-CAM). Chondroitin sulfate proteoglycan; binds to hyaluronic acid

    Polypeptides: Neurocan core protein
  4. Target

    Versican core protein

    go.drugbank.com/bio_entities/BE0004606
    TargetHumans

    May play a role in intercellular signaling and in connecting cells with the extracellular matrix. May take part in the regulation of cell motility, growth and differentiation. Binds hyaluronic acid

    Polypeptides: Versican core proteinSynonyms: Chondroitin sulfate proteoglycan core protein 2
  5. Target

    Cytochrome b-c1 complex subunit 1, mitochondrial

    go.drugbank.com/bio_entities/BE0001005
    TargetHumans

    The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase … Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation.

    Polypeptides: Cytochrome b-c1 complex subunit 1, mitochondrialSynonyms: Core protein I, Ubiquinol-cytochrome-c reductase complex core protein 1
  6. Target

    Holliday junction branch migration complex subunit RuvB

    go.drugbank.com/bio_entities/BE0002792
    TargetThermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)

    The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication … The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.

    Polypeptides: Holliday junction branch migration complex subunit RuvB
  7. Target

    Cytochrome b-c1 complex subunit 2, mitochondrial

    go.drugbank.com/bio_entities/BE0003855
    TargetHumans

    The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase … Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation.

    Polypeptides: Cytochrome b-c1 complex subunit 2, mitochondrialSynonyms: Ubiquinol-cytochrome-c reductase complex core protein 2, Core protein II
  8. Target

    Cytochrome b-c1 complex subunit 6, mitochondrial

    go.drugbank.com/bio_entities/BE0003856
    TargetHumans

    The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase … Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation.

    Polypeptides: Cytochrome b-c1 complex subunit 6, mitochondrialSynonyms: Complex III subunit 6, Complex III subunit VIII
  9. Target

    Inner membrane complex sub-compartment protein 3

    go.drugbank.com/bio_entities/BE0009269
    TargetPlasmodium falciparum (isolate 3D7)

    Polypeptides: Inner membrane complex sub-compartment protein 3
  10. Drug

    Axicabtagene ciloleucel

    go.drugbank.com/drugs/DB13915
    ApprovedInvestigational

    [A216163] Once T-cells are collected from the patient, they are genetically engineered to express anti-CD19 CARs that recognize and kill cancer cells, and are infused back into the patient.

    Categories: Complex Mixtures