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Daclatasvir
go.drugbank.com/drugs/DB09102ApprovedInvestigationalWithdrawnThe same dosing regimen can be used as first-line therapy in patients with genotype 3 without cirrhosis and second-line therapy in genotype 3 patients with compensated cirrhosis. … According to 2017 American Association for the Study of Liver Diseases (AASLD), 60mg of daclatasvir is recommended with 400mg [DB08934] for genotype 1a/b patients with or without cirrhosis as second-line
Products: DASVIR 30 (DACLATASVIR TABLETS 30 MG), DASVIR 60 (DACLATASVIR TABLETS 60 MG)Orlistat
go.drugbank.com/drugs/DB01083ApprovedInvestigationalIt was approved by the FDA for use in combination with a reduced-calorie diet in 1999. … [L11130] This drug is a generally well-tolerated and effective weight-loss aid and is now available in both over-the-counter[L31963] and prescription preparations, depending on the dosage quantity.
Products: ORLISTAT EG, ORLISTAT 120MGFlurazepam
go.drugbank.com/drugs/DB00690ApprovedIllicitA benzodiazepine derivative used mainly as a hypnotic.
Products: Somnol 15mg, Somnol 30mgTrabectedin
go.drugbank.com/drugs/DB05109ApprovedInvestigationalTrabectedin, also referred as ET-743 during its development, is a marine-derived antitumor agent discovered in the Carribean tunicate _Ecteinascidia turbinata_ and now produced synthetically. … It is approved for use in Europe, Russia and South Korea for the treatment of advanced soft tissue sarcoma.
Products: TRABECTEDINA EG, YONDELIS 1MG FOR INJECTIONMetoclopramide
go.drugbank.com/drugs/DB01233ApprovedInvestigationalIt is available in the oral tablet form or in solution, and can also be administered through the intravenous route.[T683] Metoclopramide was initially approved by the FDA in 1980.[A184922] … [L8417] One unique property of this drug is that it does not increase gastric acid secretion.
Synonyms: 2-methoxy-4-amino-5-chloro-N,N-(dimethylaminoethyl)benzamide, 4-amino-5-chloro-N-(2-(diethylamino)ethyl)-o-anisamideProducts: MCP - CT 30MG RETARD, METOPRAX 10 MG/2 ML IM/IV ENJ. COZ. ICEREN AMPUL, 5 ADETZinc citrate
go.drugbank.com/drugs/DB11154ApprovedInvestigationalIt is available as dietary supplements as a treatment of zinc deficiency and source of zinc, which is an essential trace element.
Mixtures: Collag-EN, EC + ComplexProducts: Zinc 50 mg, Zinc Tab 15mgHydrocodone
go.drugbank.com/drugs/DB00956ApprovedIllicitInvestigational[T116] It is commonly used in combination with [acetaminophen] to control moderate to severe pain. … Hydrocodone's more potent metabolite, [hydromorphone] has also found wide use as an analgesic and is frequently used in cases of severe pain.
Mixtures: Vicodin ES, Vicodin ESProducts: Robidone Syr 1mg/ml, Robidone 1mg/ml SyrGentamicin
go.drugbank.com/drugs/DB00798ApprovedInvestigationalVet approved[A234359,A234364] Although gentamicin is well-established and may be used in a variety of clinical applications, it is also associated with severe adverse effects including nephrotoxicity and ototoxicity … Gentamicin is a bactericidal aminoglycoside that was discovered and isolated from _Micromonospora purpurea_ in 1963.
Mixtures: GENTAMICINA E BETAMETASONE EG, GENTAMICINA E BETAMETASONE IDIProducts: Gentamicin(e) 120mg Liq IV 1.2mg/ml, GENTAMICINA EGThiamine
go.drugbank.com/drugs/DB00152ApprovedInvestigationalNutraceuticalVet approvedIt is soluble in water and insoluble in alcohol. Thiamine decomposes if heated. Thiamine was first discovered by Umetaro Suzuki in Japan when researching how rice bran cured patients of Beriberi. … Thiamine plays a key role in intracellular glucose metabolism and it is thought that thiamine inhibits the effect of glucose and insulin on arterial smooth muscle cell proliferation.
Mixtures: COMPLEJO B EN KOLA GRANULADA, COMPLEJO B EN KOLA GRANULADAProducts: VITAMINA B1 (TIAMINA CLORHIDRATO 100 MG./ML)EN FRASCOAMPOLLA POR 10 ML, ANEURINE TABLET 3MGBrinzolamide
go.drugbank.com/drugs/DB01194Approved[L35310,L35315] In Europe, it was also approved as a combination product with timolol in 2008.[L35320] … [A2049,A2051] Although systemic anti-carbonic anhydrase (CA) therapy has been used for almost 50 years with varying degrees of success, systemic administration results in an increase in incidences of adverse
Mixtures: AZARGA 10MG/ML+5MG/ML, AZARGA 10MG/ML + 5MG/MLProducts: BRINZOLAMIDE EG, AZOPT 10 MG/ML ATR