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DNA-binding transcriptional dual regulator CRP
go.drugbank.com/bio_entities/BE0002013TargetEscherichia coli (strain K12)A global transcription regulator, which plays a major role in carbon catabolite repression (CCR) as well as other processes. Binds cyclic AMP (cAMP) which allosterically activates DNA binding (to consensus sequence 5'-AAATGTGATCTAGATCACA...
Synonyms: cAMP receptor proteinEcamsule
go.drugbank.com/drugs/DB09534ApprovedEcamsule is an organic compound which is added to many sunscreens to filter out UVA rays. It is a benzylidene camphor derivative, many of which are known for their excellent photostability. Ecamsule has been approved for use in the U.S. ...
Mixtures: Kiehls Since 1851 Dermatologist Solutions Ultra Light Daily UV Defense Tone Up SPF 50 PA Plus Plus Plus Plus AntipollutionStabilin-1
go.drugbank.com/bio_entities/BE0010944TargetHumansActs as a scavenger receptor for acetylated low density lipoprotein. Binds to both Gram-positive and Gram-negative bacteria and may play a role in defense against bacterial infection.
Synonyms: Fasciclin, EGF-like, laminin-type EGF-like and link domain-containing scavenger receptor 1Sodium-dependent phosphate transporter 2
go.drugbank.com/bio_entities/BE0008680TransporterHumansSodium-phosphate symporter which preferentially transports the monovalent form of phosphate with a stoichiometry of two sodium ions per phosphate ion (PubMed:12205090, PubMed:15955065, PubMed:16790504, PubMed:17494632, PubMed:22327515, P...
Synonyms: Gibbon ape leukemia virus receptor 2Function: signaling receptor activityC-type lectin domain family 10 member A
go.drugbank.com/bio_entities/BE0016623TargetHumansActs as a signaling receptor at the interface of APC-T cell interactions. … Acts as an endocytic pattern recognition receptor involved in antitumor immunity.
Synonyms: DC-asialoglycoprotein receptorAmlodipine
go.drugbank.com/drugs/DB00381ApprovedInvestigationalAmlodipine, initially approved by the FDA in 1987, is a popular antihypertensive drug belonging to the group of drugs called dihydropyridine calcium channel blockers. Due to their selectivity for the peripheral blood vessels, dihydropyri...
Mixtures: RAMIPRIL HEXAL PL AM 5/5, RAMIPRIL HEXAL PL AM 5/5Categories: Angiotensin II receptor blockers (ARBs) and calcium channel blockers, P-glycoprotein inhibitorsMitochondrial potassium channel ATP-binding subunit
go.drugbank.com/bio_entities/BE0003673TransporterHumansATP-binding subunit of the mitochondrial ATP-gated potassium channel (mitoK(ATP)) (PubMed:31435016). Together with pore-forming subunit CCDC51/MITOK of the mitoK(ATP) channel, mediates ATP-dependent potassium currents across the mitochon...
Synonyms: Mitochondrial sulfonylurea-receptorTumor necrosis factor ligand superfamily member 11
go.drugbank.com/bio_entities/BE0003517TargetHumansCytokine that binds to TNFRSF11B/OPG and to TNFRSF11A/RANK. Osteoclast differentiation and activation factor. Augments the ability of dendritic cells to stimulate naive T-cell proliferation. May be an important regulator of interactions ...
Synonyms: Receptor activator of nuclear factor kappa-B ligandHepatocyte nuclear factor 4-alpha
go.drugbank.com/bio_entities/BE0004019TargetHumansTranscriptional regulator which controls the expression of hepatic genes during the transition of endodermal cells to hepatic progenitor cells, facilitating the recruitment of RNA pol II to the promoters of target genes (PubMed:30597922)...
Synonyms: Nuclear receptor subfamily 2 group A member 1Sofosbuvir
go.drugbank.com/drugs/DB08934ApprovedInvestigationalLack of significant side effects and short duration of therapy is a considerable advantage over older interferon- and ribavirin-based regimens, which were limited by infusion site reactions, reduced blood
Categories: P-glycoprotein substrates