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Leukotriene C4 Synthesis Deficiency
smpdb.ca/view/SMP0000353DiseaseA defect in LTC4 results in decreased concentrations of cysteinyl leukotrienes LTC4, LTD4 and LTE4 in plasma, spinal fluid and urine. … Leukotriene C4 synthetase deficiency is caused by a defect in the enzyme leukotriene C4 synthetase (LTC4S).
Enzymes: Prostaglandin E synthaseAntipyrine Action Pathway
smpdb.ca/view/SMP0000692Drug actionDecreased prostaglandin synthesis in many animal model's cell is caused by presence of antipyrine. … Antipyrine (also named Fenazone or Phenazone) is often used for testing the effect of other drugs on drug-metabolizing enzymes in the liver.
Enzymes: Prostaglandin E synthaseAntrafenine Action Pathway
smpdb.ca/view/SMP0000693Drug actionDecreased prostaglandin synthesis in many animal model's cell is caused by presence of antrafenine. … Prostaglandin G/H synthase 1 and 2 catalyze the arachidonic acid to prostaglandin G2, and also catalyze prostaglandin G2 to prostaglandin H2 in the metabolism pathway.
Drugs: Glutamic acid · Glutathione · Dinoprostone · Calcium · Magnesium cation · Antrafenine +5 moreEnzymes: Prostaglandin E synthaseCarprofen Action Pathway
smpdb.ca/view/SMP0000694Drug actionDecreased prostaglandin synthesis in many animal model's cell is caused by presence of Carprofen. … Prostaglandin G/H synthase 1 and 2 catalyze the arachidonic acid to prostaglandin G2, and also catalyze prostaglandin G2 to prostaglandin H2 in the metabolism pathway.
Enzymes: Prostaglandin E synthaseLumiracoxib Action Pathway
smpdb.ca/view/SMP0000699Drug actionProstaglandin G/H synthase 1 and 2 catalyze the arachidonic acid to prostaglandin G2, and also catalyze prostaglandin G2 to prostaglandin H2 in the metabolism pathway.
Drugs: Glutamic acid · Glutathione · Dinoprostone · Lumiracoxib · Calcium · Magnesium cation +5 moreEnzymes: Prostaglandin E synthaseInfluenza A virus A/Kansas/14/2017 X-327 (H3N2) antigen (UV, formaldehyde inactivated)
go.drugbank.com/drugs/DB15520ApprovedWithdrawnInactivated vaccines contain a virus particle that has been grown in media and then subsequently killed, or inactivated, through exposure to heat or chemicals such as formaldehyde 3. … Inactivated virus cannot replicate, and therefore cannot cause disease from infection, even in immunocompromised individuals.
Mixtures: INFLUVAC TETRA, SUSPENSION FOR INJECTION IN PRE-FILLED SYRINGE 0.5 MLSynonyms: Influenza A virus A/Kansas/14/2017 X-327 (H3N2) antigen (UV, formaldehyde inactivated)Guaiacol
go.drugbank.com/drugs/DB11359ApprovedGuaiacol is also present in wood smoke, as a product of pyrolysis of lignin. Guaiacol has been found in the urine of patients with neuroblastoma and pheochromocytoma. … Guaiacol is an agent thought to have disinfectant properties and used as an expectorant. Guaiacol is a phenolic natural product first isolated from Guaiac resin and the oxidation of lignin.
Mixtures: Demo Cineol Inj, NOKTOS ® ADULTOS JARABE.Synonyms: 1-hydroxy-2-methoxybenzene, 2-methoxyl-4-vinylphenolAcetohexamide
go.drugbank.com/drugs/DB00414ApprovedWithdrawnA sulfonylurea hypoglycemic agent that is metabolized in the liver to 1-hydrohexamide. Acetohexamide has been discontinued in the US market.
Synonyms: N-(p-Acetylphenylsulfonyl)-N'-cyclohexylurea, 1-[(4-acetylbenzene)sulfonyl]-3-cyclohexylurea 4-acetyl-N-(cyclohexylcarbamoyl)benzenesulfonamideCategories: Drugs Used in Diabetes, Cytochrome P-450 SubstratesLomefloxacin
go.drugbank.com/drugs/DB00978ApprovedLomefloxacin is a fluoroquinolone antibiotic, used to treat bacterial infections including bronchitis and urinary tract infections (UTIs). … Additionally, it has been employed for the prophylaxis of UTIs prior to surgery as well.
Categories: Topoisomerase II Inhibitors, 4-QuinolonesSynonyms: (±)-1-ethyl-6,8-difluoro-1,4-dihydro-7-(3-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid, 1,4-Dihydro-6,8-difluoro-1-ethyl-7-(3-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acidMethadone
go.drugbank.com/drugs/DB00333ApprovedInvestigationalIt also has a number of unique characteristics that have led to its increased use in the last two decades; in particular, methadone has a lower risk of neuropsychiatric toxicity compared to other opioids … (due to a lack of active metabolites), minimal accumulation in renal failure, good bioavailability, low cost, and a long duration of action.
Categories: Drugs Used in Opioid Dependence, Drugs Used in Addictive DisordersSynonyms: 6-Dimethylamino-4,4-diphenyl-3-heptanone