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Displaying results 2211 - 2220 of 10000 in total
  1. Drug

    Miglustat

    go.drugbank.com/drugs/DB00419
    ApprovedInvestigational

    Miglustat was first developed as an anti-HIV agent in the 1990s. … Miglustat, commonly marketed under the trade name Zavesca, is a drug used to treat Gaucher disease.

  2. Drug

    Ethoxzolamide

    go.drugbank.com/drugs/DB00311
    ApprovedWithdrawn

    Ethoxzolamide is a sulfonamide used as diuretic and in glaucoma. It inhibits carbonic anhydrase activity in proximal renal tubules to decrease reabsorption of water, sodium, potassium, bicarbonate.

  3. Drug

    Beroctocog alfa

    go.drugbank.com/drugs/DB14473
    ApprovedInvestigational

    Mixtures: ALPHANATE FOR INJECTION 250 iu/vial, ALPHANATE FOR INJECTION 1000 iu/vialProducts: FEIBA 1000 U IV INFUZYON ICIN LIYOFILIZE TOZ ICEREN FLAKON, 1 ADET, KOATE-DVI 250 IU/5 ML IV ENJEKSİYON İÇİN LİYOFİLZE TOZ İÇEREN FLAKON
  4. Drug

    Bendazac

    go.drugbank.com/drugs/DB13501
    ApprovedWithdrawn

    Bendazac is an oxyacetic acid [A39863, A39869]. … small handful of regions may continue to have the medication available for purchase and use either as a topical anti-inflammatory/analgesic cream or eye drop formulation.

  5. Drug

    Ulevostinag

    go.drugbank.com/drugs/DB14721
    Investigational

    This results in a CTL-mediated immune response against tumor cells and causes tumor cell lysis. [L4741] … administration, STING agonist MK-1454 binds to STING and activates the STING pathway, which promotes IKK-related kinase TANK-binding kinase 1 (TBK1) signaling and activates nuclear factor-kappa B (NF-kB

  6. Drug

    Zilucoplan

    go.drugbank.com/drugs/DB15636
    ApprovedInvestigational

    Zilucoplan is a 15 amino-acid, synthetic macrocyclic peptide. … It is a complement inhibitor that works to prevent the activation of C5, which is a complement protein involved in the innate immune system to initiate inflammatory responses.

  7. Drug

    Canis lupus familiaris dander

    go.drugbank.com/drugs/DB11018
    Approved

    Canis lupus familiaris dander is the dander of Canis lupus familiaris. Canis lupus familiaris dander is used in allergenic testing.

    Mixtures: Animal Allergens, AP Dog Hair and Dander Canis spp, Animal Allergens, AP Dog Hair and Dander Canis spp
  8. Target

    P2X purinoceptor 3

    go.drugbank.com/bio_entities/BE0009818
    TargetHumans

    Extracellular ATP-activated non-selective cation channel (PubMed:10440098, PubMed:27626375, PubMed:29674445, PubMed:31232692). Plays particularly important role in sensory neurons where its activation is critical for gustatory, nocicepti...

    Synonyms: ATP receptor, Purinergic receptor
  9. Target

    P2X purinoceptor 2

    go.drugbank.com/bio_entities/BE0009820
    TargetHumans

    ATP-gated nonselective transmembrane cation channel permeable to potassium, sodium and calcium (PubMed:10570044, PubMed:31636190). Activation by extracellular ATP induces a variety of cellular responses, such as excitatory postsynaptic r...

    Synonyms: ATP receptor, Purinergic receptor
  10. Drug

    Acepromazine

    go.drugbank.com/drugs/DB01614
    InvestigationalVet approved

    Acepromazine is one of the phenothiazine derivative psychotropic drugs, used little in humans, however frequently in animals as a sedative and antiemetic.

    Categories: Adrenergic alpha-1 Receptor Antagonists, Dopamine D2 Receptor Antagonists