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Iloperidone
go.drugbank.com/drugs/DB04946ApprovedInvestigational[A3024] It is considered to be a second-generation antipsychotic drug [A263552] with multiple receptor binding profile, although it shows high affinity towards 5-HT<sub>2A</sub> and dopamine D2 receptors … Iloperidone is a benzisoxazole [A263557] and an atypical antipsychotic agent that was first approved by the FDA on May 6, 2009.
Categories: Dopamine D2 Receptor Antagonists, Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeSynonyms: 1-[4-[3-[4-(6-fluoro-1,2-benzisoxazol-3-yl)-1- piperidinyl]propoxy]-3-methoxyphenyl]ethanone, 4'-(3-(4-(6-fluoro-1,2-benzisoxazol-3-yl)piperidino)propoxy)-3'-methoxyacetophenoneCarbimazole
go.drugbank.com/drugs/DB00389ApprovedAn imidazole antithyroid agent. Carbimazole is metabolized to methimazole, which is responsible for the antithyroid activity.
Categories: Heterocyclic Compounds, 1-RingSynonyms: Ethyl 3-methyl-2-thioimidazoline-1-carboxylateVarenicline
go.drugbank.com/drugs/DB01273ApprovedInvestigationalIn addition it acts on alpha3/beta4 and weakly on alpha3beta2 and alpha6-containing receptors. A full agonism was displayed on alpha7-receptors. On March 9, 2015, the U.S. … Pfizer is conducting an additional safety study of the drug, results of which are expected in late 2015.
Mixtures: CHAMPIX 0,5 MG 1 MG FILM KAPLI TABLET, 11 VE 14 ADET, CHAMPIX 0,5 MG 11 + 1 MG 42 FILM KAPLI TABLETCategories: Drugs Used in Addictive Disorders, Drugs Used in Nicotine DependenceTiapride
go.drugbank.com/drugs/DB13025InvestigationalTiapride is a selective D2 and D3 dopamine receptor blocker in the brain.
Categories: Dopamine D2 Receptor AntagonistsProducts: TIADAL 100 MG/2 ML AMPUL, 12 ADETPhenindione
go.drugbank.com/drugs/DB00498ApprovedInvestigationalAn indandione that has been used as an anticoagulant. Phenindione has actions similar to warfarin, but it is now rarely employed because of its higher incidence of severe adverse effects.
Categories: Vitamin K AntagonistsSynonyms: 2-Phenyl-1,3-indandione, 2-phenyl-1,3-diketohydrindeneFacial Skin Wrinkles
go.drugbank.com/conditions/DBCOND0057699Drugs: Botulinum toxin type ASynonyms: Lined faceColestipol
go.drugbank.com/drugs/DB00375Approved[FDA Label, F4555, F4567, L6262] In particular, as colestipol's general mechanism of action ultimately results in the decreased absorption and enhanced secretion of bile acids and lipids in the feces … Bile acid sequestrants like colestipol have been in use since the 1970s.
Categories: Compounds used in a research, industrial, or household settingSynonyms: Copolymer of bis(2-aminoethyl)amine and 2-(chloromethyl)oxiraneMolindone
go.drugbank.com/drugs/DB01618ApprovedAn indole derivative effective in schizophrenia and other psychoses and possibly useful in the treatment of the aggressive type of undersocialized conduct disorder. … Molindone has much lower affinity for D2 receptors than most antipsychotic agents and has a relatively low affinity for D1 receptors.
Categories: Dopamine D2 Receptor Antagonists, Heterocyclic Compounds, 2-RingUlceration of the mouth
go.drugbank.com/conditions/DBCOND0100372Drugs: Apremilast · Benzethonium · Benzocaine · Choline salicylate · Dequalinium · Lidocaine +7 moreSynonyms: Pain in oral cavity