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Displaying results 221 - 230 of 10000 in total
  1. Target

    Type I iodothyronine deiodinase

    go.drugbank.com/bio_entities/BE0009854
    EnzymeTargetHumans

    Plays a crucial role in the metabolism of thyroid hormones (TH) and has specific roles in TH activation and inactivation by deiodination (PubMed:12586771, PubMed:32718224, PubMed:18821722). Catalyzes the deiodination of L-thyroxine (T4) ...

    Polypeptides: Type I iodothyronine deiodinaseSynonyms: Type-I 5'-deiodinase
  2. Drug

    Gemfibrozil

    go.drugbank.com/drugs/DB01241
    ApprovedInvestigational

    [A185777,L8525] Gemfibrozil is not a first line treatment and is prescribed to patients who have not responded adequately to weight loss, diet, exercise, and other medications. … Gemfibrozil is a fibric acid agent, similar to [clofibrate], used to treat Type IIb, IV, and V hyperlipidemias.

    Synonyms: 2,2-Dimethyl-5-(2,5-xylyloxy)valeriansäure, 2,2-Dimethyl-5-(2,5-xylyloxy)valeric acidCategories: Non-statin Hypolipidemic Agents Indicated for Hyperlipidemia, Cytochrome P-450 Substrates
  3. Indication

    Stage I Breast Cancer

    go.drugbank.com/conditions/DBCOND0029483
    Drugs: Anastrozole · Exemestane · Hyaluronidase (human recombinant) · Letrozole · Olaparib · Pertuzumab +1 more
    Synonyms: Stage I Breast Cancer, Stage I Breast Carcinoma
  4. Drug

    Cloxacillin

    go.drugbank.com/drugs/DB01147
    ApprovedInvestigationalVet approved

    A semi-synthetic penicillin antibiotic which is a chlorinated derivative of [oxacillin].

    Synonyms: (3-(o-chlorophenyl)-5-methyl-4-isoxazolyl)penicillin, 6-(3-(o-chlorophenyl)-5-methyl-4-isoxazolecarboxamido)penicillanic acidCategories: Heterocyclic Compounds, 2-Ring
  5. Drug

    Hydrogen peroxide

    go.drugbank.com/drugs/DB11091
    ApprovedInvestigationalVet approved

    Hydrogen peroxide is also considered as a generally recognized as safe compound by the FDA [L2024]; it is used as an antimicrobial agent in starch and cheese products, and as an oxidizing and reducing … As a natural product of metabolism, it readily undergoes decomposition by catalase in normal cells [L2024].

    Mixtures: K-100, K-100Categories: Compounds used in a research, industrial, or household setting
  6. Drug

    Abciximab

    go.drugbank.com/drugs/DB00054
    ApprovedWithdrawn

    It also binds to vitronectin (αvβ3) receptor found on platelets and vessel wall endothelial and smooth muscle cells. … Abciximab binds to the glycoprotein (GP) IIb/IIIa receptor of human platelets and inhibits platelet aggregation by preventing the binding of fibrinogen, von Willebrand factor, and other adhesive molecules

    Products: ReoPro 2 mg/ml Injektionslösung oder Infusionslösung, CLOTİNAB 10 MG/5 ML IV ENJEKSİYON İÇİN ÇÖZELTİ İÇEREN FLAKON, 1 ADET
  7. Drug

    Ascorbic acid

    go.drugbank.com/drugs/DB00126
    ApprovedInvestigationalNutraceutical

    Ascorbic acid is an essential nutrient in human diets, and necessary to maintain connective tissue and bone. … A six carbon compound related to glucose. It is found naturally in citrus fruits and many vegetables.

    Synonyms: Vitamin C, Vitamin-CMixtures: Formula No. 2 Plus K Liq, Prenatal Vitamin No 53 Iron Fum Folic Acid Docusate CA DHA
  8. Drug

    Trimipramine

    go.drugbank.com/drugs/DB00726
    ApprovedInvestigational

    Tricyclic antidepressant similar to imipramine, but with more antihistaminic and sedative properties.

    Categories: Non-Selective Monoamine Reuptake Inhibitors, Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeSynonyms: 10,11-dihydro-N,N,β-trimethyl-5H-dibenz[b,f]azepine-5-propanamine, 5-(γ-dimethylamino-β-methylpropyl)-10,11-dihydro-5H-dibenzo[b,f]azepine
  9. Drug

    Arbutin

    go.drugbank.com/drugs/DB11217
    Approved

    Arbutin is available in both natural and synthetic forms; it can be synthesized from acetobromglucose and [DB09526] [F43]. … Arbutin was shown to be less cytotoxic to melanocytes in culture compared to [DB09526] [A32942].

    Synonyms: hydroquinone O-β-D-glucopyranoside, Hydroquinone-O-beta-D-glucopyranosideMixtures: OHUI White Extreme Illuminating Pact No.10, OHUI White Extreme Illuminating Pact No.10
  10. Drug

    Iopromide

    go.drugbank.com/drugs/DB09156
    Approved

    [A260751] Approved by the FDA in 1995 and Health Canada in 1994 under the brand name ULTRAVIST, iopromide is used in radiological diagnosis, including, but not limited to, intra-arterial digital subtraction … [A225366] Although iopromide can cause several serious adverse effects, including cardiac events, thromboembolism, hypersensitivity reaction, and even death if administered intrathecally inadvertently,

    Synonyms: N,N'-bis(2,3-dihydroxypropyl)-2,4,6-triiodo-5-[(methoxyacetyl)amino]-N-methylisophthalamideCategories: Compounds used in a research, industrial, or household setting, X-Ray Contrast Activity