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Displaying results 221 - 230 of 8135 in total
  1. Drug

    Dexlansoprazole

    go.drugbank.com/drugs/DB05351
    Approved

    Compared to the older generation of PPIs (which includes [DB00213], [DB00338], and [DB00448]),[A178084] dexlansoprazole has a unique pharmacokinetic profile due to its delayed-release and dual-delivery

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesProducts: DEXOPRAL ® 60 CAPSULA DE LIBERACIÓN RETARDADA, DEXOPRAL ® 30 CAPSULA DE LIBERACIÓN RETARDADA
  2. Indication

    Duodenal ulcer haemorrhage

    go.drugbank.com/conditions/DBCOND0010674
    Drugs: Somatostatin
    Synonyms: Bleeding DU
  3. Drug

    Bosutinib

    go.drugbank.com/drugs/DB06616
    ApprovedInvestigational

    Philadelphia chromosome is a hallmark of CML due to the reciprocal translocation t(9;22)(q34;q11), resulting in a BCR-ABL fusion protein. … -alkoxy-3-quinolinecarbonitrile that functions as a potent, dual SRC and ABL tyrosine kinase inhibitor indicated for chronic myelogenous leukemia (CML), specifically Philadelphia chromosome-positive (Ph

    Categories: P-glycoprotein substrates, Cytochrome P-450 SubstratesProducts: BOSUTINIB DR. REDDY?S
  4. Drug

    Etamsylate

    go.drugbank.com/drugs/DB13483
    Investigational

    Products: STAN KA TABLETAS
  5. Drug

    Glycopyrronium

    go.drugbank.com/drugs/DB00986
    ApprovedInvestigationalVet approved

    [A233535,A233540] Early research into glycopyrronium use was for its indication as an adjunct therapy in the treatment of peptic ulcers.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 SubstratesProducts: Glyrx-PF, GLYCO-P
  6. Drug

    Methylphenidate

    go.drugbank.com/drugs/DB00422
    ApprovedInvestigational

    [A177550] Clinical findings have shown that children with ADHD have an abnormality in the dopamine transporter gene (DAT1), the D4 receptor gene (DRD-4), and/or the D2 receptor gene that may be at least … In contrast, low doses are found to selectively activate NE and DA neurotransmission within the prefrontal cortex which is an area of the brain thought to play a prominent role in ADHD pathophysiology,

    Products: Jornay PM, JORNAY PM Extended-Release
  7. Drug

    Acetaminophen

    go.drugbank.com/drugs/DB00316
    ApprovedInvestigational

    [L5783] Due to the possibility of fatal overdose and liver failure associated with the incorrect use of acetaminophen, it is important to follow current and available national and manufacturer dosing guidelines … [L5786,L5789,L4396] On September 22, 2025, the US FDA initiated a labeling change for acetaminophen products suggesting that the use of acetaminophen by pregnant women may be associated with an increased

    Synonyms: p-acetamidophenol, p-acetaminophenolInternational brands: Oraphen-PD
  8. Drug

    Vecuronium

    go.drugbank.com/drugs/DB01339
    ApprovedInvestigational

    Monoquaternary homolog of pancuronium. A non-depolarizing neuromuscular blocking agent with shorter duration of action than pancuronium. Its lack of significant cardiovascular effects and lack of dependence on good kidney function for el...

    Categories: P-glycoprotein substratesProducts: BROMURO DE VECURONIO 10MG/VIAL, BROMURO DE VECURONIO 4 MG/VIAL POLVO LIOFILIZADO PARA RECONSTITUIR A SOLUCION INYECTABLE
  9. Drug

    Chloral hydrate

    go.drugbank.com/drugs/DB01563
    ApprovedIllicitInvestigationalVet approved

    It is no longer considered useful as an anti-anxiety medication.

    Products: HIDRATO DE CLORAL 10%SOLUCION ORAL(GOTAS)
  10. Drug

    Methylene blue

    go.drugbank.com/drugs/DB09241
    ApprovedInvestigational

    clinical trials to be an inhibitor of Tau protein aggregation. … Its use as an urinary tract antiseptic has also been investigated.

    Mixtures: Urin D/S, Prosed/DSCategories: P-glycoprotein inhibitors, P-glycoprotein substrates