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Acetylcarnitine
go.drugbank.com/drugs/DB08842ApprovedInvestigationalIn human plasma and tissues, acetylcarnitine is the most predominant acylated ester of carnitine, which is an amino acid derivative that is made in the kidney, liver, and brain from lysine and methionine … Acetylcarnitine can be synthesized, but it is also naturally found in adequate amounts in healthy humans.
Categories: Psychostimulants, Agents Used for ADHD and NootropicsGadobutrol
go.drugbank.com/drugs/DB06703ApprovedInvestigationalGadobutrol is a second-generation extracellular non-ionic macrocyclic GBCA (gadolinium-based contrast agent) used in magnetic resonance imaging (MRI) in adults and children older than 2 years of age. … [A7001] Like other GBCA, gadobutrol usage carries the risk of nephrogenic systemic fibrosis (NSF) due to the dissociation of gadolinium from the chelates, although gadobutrol tends to have a lower risk
Oseltamivir
go.drugbank.com/drugs/DB00198ApprovedInvestigationalOseltamivir exerts its antiviral activity by inhibiting the activity of the viral neuraminidase enzyme found on the surface of the virus, which prevents budding from the host cell, viral replication, and … [A180583] According to the CDC, data from clinical trials and observational studies have demonstrated that early antiviral treatment can shorten the duration of fever and illness symptoms, and may reduce
Products: Tamiflu capsule 30mg, Tamiflu Capsule 30mgAlpha-1-proteinase inhibitor
go.drugbank.com/drugs/DB00058ApprovedInvestigationalHuman alpha-1 proteinase inhibitor or alpha-1-antitrypsin, prepared from human plasma via Cohn alcohol fractionation followed by PEG and zinc chloride fractionation.
Categories: Enzymes and Coenzymes, Blood and Blood Forming OrgansProducts: Prolastin 1000 mg - Pulver und Lösungsmittel zur Herstellung einer Infusionslösung, Prolastin 4000 mg - Pulver und Lösungsmittel zur Herstellung einer InfusionslösungDeferoxamine
go.drugbank.com/drugs/DB00746ApprovedInvestigationalNatural product isolated from Streptomyces pilosus. It forms iron complexes and is used as a chelating agent, particularly in the mesylate form.
Inflammatory Bowel Diseases (IBD)
go.drugbank.com/conditions/DBCOND0069946Drugs: PhthalylsulfathiazoleSynonyms: (Noninfective enteritis and/or colitis) or (inflammatory bowel disease) or (noninfective diarrhoea)Ocriplasmin
go.drugbank.com/drugs/DB08888ApprovedWithdrawnOcriplasmin is a protein made up of 249 amino acids and has two peptide chains. Agent for pharmacologic vitreolysis; thrombolytic agent. FDA approved in October 17, 2012. … Ocriplasmin is a recombinant truncated form of human plasmin with a molecular weight of 27.2 kDa produced by recombinant DNA technology in a Pichia pastoris expression system.
Categories: Enzymes and Coenzymes, Amino Acids, Peptides, and ProteinsAtogepant
go.drugbank.com/drugs/DB16098ApprovedInvestigationalIt was developed by AbbVie and received FDA approval under the brand name Qulipta in September 2021. … [L38814] While its approval was predated by two other members of the same drug family, namely [ubrogepant] and [rimegepant], these agents are indicated only for abortive migraine therapy - atogepant is
Niraparib
go.drugbank.com/drugs/DB11793ApprovedInvestigational[L43277] Niraparib was approved by the European Commission on November 16, 2017 [L43742] and by Health Canada on June 27, 2019. … [L43277] Niraparib is selective towards PARP-1 and PARP-2.
Categories: niraparib and abiraterone, Antineoplastic and Immunomodulating AgentsComplement C3
go.drugbank.com/bio_entities/BE0003455TargetHumansPrecursor of non-enzymatic components of the classical, alternative, lectin and GZMK complement pathways, which consist in a cascade of proteins that leads to phagocytosis and breakdown of pathogens and
Synonyms: C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1