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Solute carrier family 15 member 1
go.drugbank.com/bio_entities/BE0001018TransporterTargetHumansElectrogenic proton-coupled amino-acid transporter that transports oligopeptides of 2 to 4 amino acids with a preference for dipeptides. Transports neutral and monovalently charged peptides with a proton to peptide stoichiometry of 1:1 o...
Polypeptides: Solute carrier family 15 member 1Fenproporex
go.drugbank.com/drugs/DB01550ApprovedIllicitWithdrawnIt is listed as an illicit substance in many countries due to addiction issues and listed as a prohibited substance by the World Anti-Doping Agency. … effects are less notorious than with some other agents such as diethylpropion and mazindol. [7] In the United States fenproporex was never approved by the FDA for clinical use due to a lack of efficacy
International brands: Desobesi-MProducts: IFA-DIETY A. P.Norgestimate
go.drugbank.com/drugs/DB00957ApprovedInvestigational[A191068] It was developed by Ortho Pharmaceutical Corporation as part of an effort to develop new hormonal contraceptives with reduced adverse effects. … [A191068] It is commonly formulated with [ethinylestradiol] as a combined oral contraceptive that can also be used to treat moderate acne vulgaris.
Synonyms: d-13β-Ethyl-17α-ethynyl-17β-acetoxygon-4-en-3-one oximeCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A InducersCarfentanil
go.drugbank.com/drugs/DB01535IllicitInvestigationalVet approvedIt has a quantitative potency approximately 10,000 times that of morphine and 100 times that of fentanyl, with activity in humans starting at about 1 microgram. … It is marketed under the trade name Wildnil as a general anaesthetic agent for large animals.
Seasonal Allergic Rhinitis
go.drugbank.com/conditions/DBCOND0030588Drugs: Acrivastine · Azelastine · Beclomethasone dipropionate · Bilastine · Cetirizine · Ciclesonide +22 moreSynonyms: SARS, SARS VirusBromothalonil
go.drugbank.com/drugs/DB14199ApprovedIt is also a known allergen and dermatological irritant that has been banned in many EU countries due to increasing rates of contact allergy [A34322]. … In 2005, MDBGN was named in the top 15 most frequently positive allergens identified in patch tests by the North American Contact Dermatitis Group (NACDG)[A34326].
Categories: Compounds used in a research, industrial, or household settingMobocertinib
go.drugbank.com/drugs/DB16390ApprovedInvestigationalWithdrawn1.5- to 10-fold lower than those required to inhibit wild-type EGFR. … [A238828] Mobocertinib appears to be an effective means of treating this otherwise treatment-resistant NSCLC, exerting an inhibitory effect on _EGFR_ exon 20 insertion mutant variants at concentrations
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesMitogen-activated protein kinase kinase kinase 15
go.drugbank.com/bio_entities/BE0009466TargetHumansSerine/threonine kinase which acts as a component of the MAP kinase signal transduction pathway (PubMed:20362554, PubMed:26732173). Once activated, acts as an upstream activator of the p38 MAPK signal transduction cascade through the pho...
Polypeptides: Mitogen-activated protein kinase kinase kinase 15Synonyms: MEKK 15, MEK kinase 15Lebrikizumab
go.drugbank.com/drugs/DB11914ApprovedInvestigationalbody weight of at least 40 kg. … Lebrikizumab is a monoclonal antibody that binds to IL-13 with high affinity and slow off-rate.[L51374] It binds to a different epitope compared [tralokinumab].
DL-dimyristoylphosphatidylcholine
go.drugbank.com/drugs/DB11283ApprovedA synthetic phospholipid used in liposomes and lipid bilayers for the study of biological membranes. It is used in commercial drug preparations to solubilize drugs for injection [A32711]
Synonyms: DL-dimyristoylphosphatidylcholine, Dimyristoylphosphatidylcholine, DL-Categories: Compounds used in a research, industrial, or household setting