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Methimazole
go.drugbank.com/drugs/DB00763ApprovedInvestigational[A184733] Traditionally, methimazole has been preferentially used over propylthiouracil due to the risk of fulminant hepatotoxicity carried by the latter,[A184757] with propylthiouracil being preferred
Categories: Cytochrome P-450 CYP1A2 Inhibitors, Cytochrome P-450 CYP2A6 InhibitorsProducts: Thiamazol Sandoz 20 mg - TablettenDoxylamine
go.drugbank.com/drugs/DB00366ApprovedInvestigationalVet approvedHistamine H1 antagonist with pronounced sedative properties. It is used in allergies and as an antitussive, antiemetic, and hypnotic. Doxylamine has also been administered in veterinary applications and was formerly used in parkinsonism.
Mixtures: Safetussin PM, Safetussin PMProducts: HOGGAR NIGHT TABLETTENNaphazoline
go.drugbank.com/drugs/DB06711ApprovedIt acts to decrease congestion and is found in many over the counter (OTC) eye drops and nasal preparations[L5804,L5807].
Products: Pi Yen Chin, Pi Yuan ChinDorzolamide
go.drugbank.com/drugs/DB00869ApprovedInvestigational[A1304] First marketed in 1995,[A190624] dorzolamide is available in ophthalmic solutions as monotherapy marketed as Trusopt [L11377] or in combination with [timolol] as Cosopt PF.[L11380]
Mixtures: Cosopt PF, Cosopt PFCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C9 SubstratesNeomycin
go.drugbank.com/drugs/DB00994ApprovedInvestigationalVet approved[L10716] Neomycin is also available in over-the-counter topical products to prevent minor skin infections.
Mixtures: KRIM PI KANG SHUANG, PS-2261 Triple Antibiotic, 0.5gProducts: NEOMYCIN PF-50% W/W POWDERPropylene glycol
go.drugbank.com/drugs/DB01839ApprovedInvestigationalA clear, colorless, viscous organic solvent and diluent used in pharmaceutical preparations.
Mixtures: Hydration PF, Systane Hydration PF Preservative FreeProducts: Systane COMPLETE PFSulfasalazine
go.drugbank.com/drugs/DB00795ApprovedInvestigationalSulfasalazine is an anti-inflammatory drug structurally related to salicylates and other non-steroidal anti-inflammatory drugs. It is indicated for managing inflammatory diseases such as ulcerative colitis and rheumatoid arthritis (RA). ...
Synonyms: 5-(p-(2-Pyridylsulfamyl)phenylazo)salicylic acid, 5-((p-(2-Pyridylsulfamoyl)phenyl)azo)salicylic acidProducts: Salazopyrin 500 mg - TablettenHydroxychloroquine
go.drugbank.com/drugs/DB01611ApprovedInvestigationalHydroxychloroquine is a racemic mixture consisting of an R and S enantiomer. Hydroxychloroquine is an aminoquinoline like chloroquine. It is a commonly prescribed medication in the treatment of uncomplicated malaria, rheumatoid arthritis...
Categories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesProducts: PLAQUENIL 200MG TABLETTENAmbroxol
go.drugbank.com/drugs/DB06742ApprovedInvestigationalAmbroxol is a secretolytic agent used in the treatment of respiratory diseases associated with viscid or excessive mucus. It is the active ingredient of Mucosolvan, Lasolvan or Mucoangin. The substance is a mucoactive drug with several p...
Mixtures: Mucospas - Tabletten, EBROMIN-PCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesAbiraterone
go.drugbank.com/drugs/DB05812ApprovedInvestigationalAbiraterone is a potent, irreversible, and selective inhibitor of 17 αhydroxylase/C17,20-lyase (CYP17), an enzyme expressed in testicular, adrenal, and prostatic tumour tissues, to regulate androgen biosynthesis. Abiraterone was first ap...
Categories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesProducts: Abirateron Aristo 250 mg Tabletten, Abirateron Fresenius Kabi 250 mg Tabletten