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Displaying results 231 - 240 of 302 in total
  1. Target

    NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial

    go.drugbank.com/bio_entities/BE0000729
    TargetEnzymeHumans

    Essential for the catalytic activity of complex I (PubMed:22036843, PubMed:30922174). Essential for the assembly of complex I (By similarity). … Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor

    Synonyms: Complex I-49kD
  2. Target

    Protein SLC31A2

    go.drugbank.com/bio_entities/BE0003662
    TransporterHumans

    Does not function as a copper(1+) importer in vivo (By similarity). However, in vitro functions as a low-affinity copper(1+) importer (PubMed:17617060, PubMed:17944601). … export and modulates the copper and cisplatin accumulation via SLC31A1 (By similarity)

    Synonyms: Copper transporter 2Function: copper ion transmembrane transporter activity
  3. Target

    NADH dehydrogenase [ubiquinone] iron-sulfur protein 5

    go.drugbank.com/bio_entities/BE0000089
    TargetHumans

    Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. … Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone

    Synonyms: Complex I-15 kDa
  4. Target

    Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1

    go.drugbank.com/bio_entities/BE0020167
    EnzymeHumans

    Glycosyltransferase that generates the core 1 O-glycan Gal-beta1-3GalNAc-alpha1-Ser/Thr (T antigen), which is a precursor for many extended O-glycans in glycoproteins (PubMed:11677243).

    Synonyms: Core 1 beta3-Gal-T1, Core 1 O-glycan T-synthase
  5. Target

    3-ketoacyl-CoA thiolase

    go.drugbank.com/bio_entities/BE0004257
    TargetPseudomonas fragi

    Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.

    Synonyms: Fatty acid oxidation complex subunit beta
  6. Target

    NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial

    go.drugbank.com/bio_entities/BE0000037
    TargetHumans

    Essential for the catalytic activity and assembly of complex I (PubMed:22499348) … Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor

    Synonyms: Complex I-23kD
  7. Target

    NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial

    go.drugbank.com/bio_entities/BE0000093
    TargetHumans

    Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. … Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone

    Synonyms: Complex I-13kD-A
  8. Target

    NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial

    go.drugbank.com/bio_entities/BE0000307
    TargetEnzymeHumans

    Essential for the catalytic activity of complex I (PubMed:17275378) … Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor

    Synonyms: Complex I-20kD
  9. Target

    Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial

    go.drugbank.com/bio_entities/BE0000176
    TargetEnzymeHumans

    Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone

    Synonyms: Flavoprotein subunit of complex II
  10. Target

    NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7

    go.drugbank.com/bio_entities/BE0000512
    TargetHumans

    Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. … Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone

    Synonyms: Complex I-B18