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Trolamine salicylate
go.drugbank.com/drugs/DB11079ApprovedAs with other salicylates, trolamine salicylate is an inhibitor of cyclo-oxygenase (COX) enzymes with no reported selectivity towards a specific enzyme isoform. … Trolamine salicylate is an organic compound or a salt formed between triethanolamine and salicylic acid. Triethanolamine neutralizes the acidity of the salicylic acid.
Categories: Non COX-2 selective NSAIDSProducts: Antiphlogistine Rub A-535 No Odour Fmla Ont, Ultracin TSt. John's Wort
go.drugbank.com/drugs/DB01323ApprovedNutraceuticalMixtures: S. R. FormulaCategories: P-glycoprotein inducers, Cytochrome P-450 SubstratesCarbimazole
go.drugbank.com/drugs/DB00389ApprovedAn imidazole antithyroid agent. Carbimazole is metabolized to methimazole, which is responsible for the antithyroid activity.
Categories: Heterocyclic Compounds, 1-RingSynonyms: Ethyl 3-methyl-2-thioimidazoline-1-carboxylateRilmenidine
go.drugbank.com/drugs/DB11738ApprovedWithdrawnRilmenidine has been used in trials studying the treatment of Hypertension and Chronic Kidney Disease.
Categories: Heterocyclic Compounds, 1-Ring, Adrenergic alpha-2 Receptor AgonistsProducts: Iterium 1 mg - Tabletten, HYPERIUM 1 MG TABLET, 30 ADETInfluenza B virus B/Brisbane/60/2008 hemagglutinin antigen (formaldehyde inactivated)
go.drugbank.com/drugs/DB14385ApprovedInvestigationalWithdrawnA seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. … Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed, or inactivated, through exposure to heat or chemicals such as formaldehyde 3.
Mixtures: Fluarix 2010/2011Categories: Inactivated Influenza B Virus VaccineMoxonidine
go.drugbank.com/drugs/DB09242ApprovedInvestigationalWithdrawnMoxonidine is a new-generation centrally acting antihypertensive drug approved for the treatment of mild to moderate essential hypertension. … As well, moxonidine has been shown to present blood pressure-independent beneficial effects on insulin resistance syndrome.
Categories: Heterocyclic Compounds, 1-Ring, Adrenergic alpha-2 Receptor AgonistsSynonyms: (2R,4R)-1-[(2S)-5-[(aminoiminomethyl)amino]-1-oxo-2-[[(1,2,3,4-tetrahydro-3-methyl-8- quinolinyl)sulfonyl]amino]pentyl]-4-methyl-2-piperidinecarboxylic acidAnkle spasticity following a stroke or traumatic brain injury
go.drugbank.com/conditions/DBCOND0133858Drugs: Clostridium botulinumSynonyms: Ankle spasticity following a stroke or traumatic brain injurySulfaquinoxaline
go.drugbank.com/drugs/DB11464ExperimentalVet approvedSulfaquinoxaline is a veterinary medicine which can be given to cattle and sheep to treat coccidiosis.It is available in Pakistan with Sanna Laboratories in combination with Amprolium and Vitamin K as
Products: TP-SQ 250 WSP Sulfaquinoxaline 250 mg/g Powder, COCCI 25%W/W PREMIX POWDER3-hydroxy-3-methylglutaryl-coenzyme A reductase
go.drugbank.com/bio_entities/BE0000574TargetEnzymeHumansHMGCR is the main target of statins, a class of cholesterol-lowering drugs (PubMed:11349148, PubMed:18540668, PubMed:36745799) … Catalyzes the conversion of (3S)-hydroxy-3-methylglutaryl-CoA (HMG-CoA) to mevalonic acid, the rate-limiting step in the synthesis of cholesterol and other isoprenoids, thus plays a critical role in cellular
Polypeptides: 3-hydroxy-3-methylglutaryl-coenzyme A reductaseFunction: coenzyme A bindingAcetyl-coenzyme A synthetase 2-like, mitochondrial
go.drugbank.com/bio_entities/BE0000746TargetHumansInvolved in thermogenesis under ketogenic conditions, using acetate as a vital fuel when carbohydrate availability is insufficient (By similarity) … Can also utilize propionate with a much lower affinity (By similarity). Provides acetyl-CoA that is utilized mainly for oxidation under ketogenic conditions (By similarity).
Polypeptides: Acetyl-coenzyme A synthetase 2-like, mitochondrial