Search
Attapulgite
go.drugbank.com/drugs/DB01574ApprovedVet approvedWithdrawnAttapulgite is a magnesium aluminium phyllosilicate which occurs in a type of clay soil common to the Southeastern United States. … When used in medicine, it physically binds to acids and toxic substances in the stomach and digestive tract. For that reason, it has often been used in antidiarrheal medications.
Oxethazaine
go.drugbank.com/drugs/DB12532ApprovedWithdrawn[L1113] It is also in the list of approved derivatives of herbal products by the EMA.[L2816] … Its actions have shown to relieve dysphagia, relieve pain due to reflux, chronic gastritis, and duodenal ulcer.
Penbutolol
go.drugbank.com/drugs/DB01359ApprovedInvestigationalWithdrawnPenbutolol also demonstrates high binding affinity to the 5-hydroxytryptamine receptor 1A with antagonistic effects. … Penbutolol is a drug in the beta-blocker class used to treat hypertension. Penbutolol binds both beta-1 and beta-2 adrenergic receptors, rendering it a non-selective beta-blocker.
Categories: Serotonin Receptor Antagonists, Serotonin 5-HT1 Receptor AntagonistsPrimaquine
go.drugbank.com/drugs/DB01087ApprovedInvestigationalIt has also been used to prevent transmission of falciparum malaria by those returning to areas where there is a potential for re-introduction of malaria. … (From Martindale, The Extra Pharmacopeia, 30th ed, p404)
Imlifidase
go.drugbank.com/drugs/DB15258ApprovedInvestigationalto non-self HLA antigens, face additional barriers to transplantation. … [L28001] As a result, the risk of antibody-mediated rejection is reduced allowing kidney transplantation in highly sensitized patients to proceed.[A225836,L28001]
Polyethylene glycol 300
go.drugbank.com/drugs/DB11161ApprovedLow molecular weight glycols are observed to exhibit antibacterial properties as well. PEG 300 is found in eye drops as a lubricant to temporarily relieve redness, burning and irritation of the eyes. … Polyethylene glycols are widely used in biochemistry, structural biology, and medicine in addition to pharmaceutical and chemical industries.
Etripamil
go.drugbank.com/drugs/DB12605ApprovedInvestigational) to sinus rhythm in adults. … [A275243, A275248] The nasal formulation of etripamil was first approved by the FDA on December 12, 2025 for the conversion of acute symptomatic episodes of paroxysmal supraventricular tachycardia (PSVT
Ceritinib
go.drugbank.com/drugs/DB09063ApprovedInvestigationalcarcinogenesis and seems to drive the malignant phenotype. … This occurrence led to development of novel second-generation ALK inhibitors such as ceritinib to overcome crizotinib resistance.
Categories: Receptor Protein-Tyrosine Kinases, antagonists & inhibitorsFlutemetamol (18F)
go.drugbank.com/drugs/DB09151ApprovedInvestigationalFlutemetamol (18F), an analogue of [(11)C]PIB,[A18519] is a radioactive diagnostic drug used for Positron Emission Tomography (PET) imaging of the brain to estimate β amyloid neuritic plaque density. … It is used to evaluate Alzheimer's disease (AD) or other causes of cognitive decline as an Aβ-specific positron emission tomography (PET) ligand.[L35029]
Canakinumab
go.drugbank.com/drugs/DB06168ApprovedInvestigationalClinical trials have established the administration of canakinumab every 2 weeks to be safe and effective, offering a considerable advantage over the existing treatment with the human IL-1 receptor antagonist … Canakinumab binds to human IL-1β and neutralizes its inflammatory activity by blocking its interaction with IL-1 receptors, but it does not bind IL-1alpha or IL-1 receptor antagonist (IL-1ra).