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Displaying results 2391 - 2400 of 10000 in total
  1. Drug

    Oxabolone cipionate

    go.drugbank.com/drugs/DB13185
    Experimental

    It is considered as a performance enhancing drug thus is prohibited from use in sports. … Oxabolone cipionate is the C17β cypionate ester and a prodrug of [DB01500]. A synthetic anabolic-androgenic (AAS) steroid, it is a derivative of 19-nortestosterone (nandrolone).

    Categories: Estradiol Congeners
  2. Drug

    L-Acetylleucine

    go.drugbank.com/drugs/DB16956
    ApprovedInvestigational

    Levacetylleucine (L-acetylleucine) is a modified acetylated derivative of the amino acid [leucine]. The racemic (i.e. DL-) form has been available in France since 1957 for the treatment of vertigo. … [A264439] In September 2024, the FDA approved levacetylleucine for the treatment of select patients with NPC.[L51444]

  3. Drug

    Ferric pyrophosphate

    go.drugbank.com/drugs/DB09147
    ApprovedInvestigational

    Ferric pyrophosphate is an iron replacement product. … The ferric ion is strongly complexed by pyrophosphate.[A31979] It presents an increasing interest as this insoluble form can be milder in the gastrointestinal tract and present higher bioavailability.

  4. Drug

    Elivaldogene autotemcel

    go.drugbank.com/drugs/DB16746
    Approved

    It is used to provide functional copies of human adrenoleukodystrophy protein (ALDP) in patients with adrenoleukodystrophy,[L39491] an X-linked genetic disorder characterized by missing or non-functional … [L40298] Cerebral adrenoleukodystrophy is an inflammatory cerebral phenotype that more commonly affects young men: it is associated with progressive brain function loss and poor survival rates without

  5. Target

    High affinity immunoglobulin epsilon receptor subunit alpha

    go.drugbank.com/bio_entities/BE0000015
    TargetHumans

    High-affinity receptor for immunoglobulin epsilon/IgE. Mediates IgE effector functions in myeloid cells.

    Polypeptides: High affinity immunoglobulin epsilon receptor subunit alphaSynonyms: IgE Fc receptor subunit alpha
  6. Target

    High affinity immunoglobulin gamma Fc receptor I

    go.drugbank.com/bio_entities/BE0000710
    TargetCarrierHumans

    High affinity receptor for the Fc region of immunoglobulins gamma. Functions in both innate and adaptive immune responses.

    Polypeptides: High affinity immunoglobulin gamma Fc receptor ISynonyms: IgG Fc receptor I
  7. Target

    Gamma-aminobutyric acid receptor subunit alpha-6

    go.drugbank.com/bio_entities/BE0000764
    TargetHumans

    Alpha subunit of the heteropentameric ligand-gated chloride channel gated by gamma-aminobutyric acid (GABA), a major inhibitory neurotransmitter in the brain (PubMed:8632757). GABA-gated chloride channels, also named GABA(A) receptors (G...

    Polypeptides: Gamma-aminobutyric acid receptor subunit alpha-6Synonyms: GABA(A) receptor subunit alpha-6
  8. Target

    Tyrosine-protein phosphatase non-receptor type 4

    go.drugbank.com/bio_entities/BE0000980
    TargetHumans

    Phosphatase that plays a role in immunity, learning, synaptic plasticity or cell homeostasis (PubMed:25825441, PubMed:27246854). Regulates neuronal cell homeostasis by protecting neurons against apoptosis (PubMed:20086240). Negatively re...

    Polypeptides: Tyrosine-protein phosphatase non-receptor type 4
  9. Target

    Tumor necrosis factor receptor superfamily member 1A

    go.drugbank.com/bio_entities/BE0001139
    TargetHumans

    Receptor for TNFSF2/TNF and homotrimeric TNFSF1/lymphotoxin-alpha. The adapter molecule FADD recruits caspase-8 to the activated receptor.

    Polypeptides: Tumor necrosis factor receptor superfamily member 1ASynonyms: Tumor necrosis factor receptor 1, Tumor necrosis factor receptor type I
  10. Target

    Triggering receptor expressed on myeloid cells 1

    go.drugbank.com/bio_entities/BE0001288
    TargetHumans

    By also promoting the amplification of inflammatory signals that are initially triggered by Toll-like receptor (TLR) and NOD-like receptor engagement, plays a major role in the pathophysiology of acute … Cell surface receptor that plays important roles in innate and adaptive immunity by amplifying inflammatory responses (PubMed:10799849, PubMed:21393102).

    Polypeptides: Triggering receptor expressed on myeloid cells 1Synonyms: Triggering receptor expressed on monocytes 1