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Displaying results 2401 - 2410 of 10000 in total
  1. Drug

    Trolamine salicylate

    go.drugbank.com/drugs/DB11079
    Approved

    As with other salicylates, trolamine salicylate is an inhibitor of cyclo-oxygenase (COX) enzymes with no reported selectivity towards a specific enzyme isoform. … Trolamine salicylate is an organic compound or a salt formed between triethanolamine and salicylic acid. Triethanolamine neutralizes the acidity of the salicylic acid.

    Categories: Non COX-2 selective NSAIDSProducts: Antiphlogistine Rub A-535 No Odour Fmla Ont, Ultracin T
  2. Drug

    St. John's Wort

    go.drugbank.com/drugs/DB01323
    ApprovedNutraceutical

    Mixtures: S. R. FormulaCategories: P-glycoprotein inducers, Cytochrome P-450 Substrates
  3. Drug

    Carbimazole

    go.drugbank.com/drugs/DB00389
    Approved

    An imidazole antithyroid agent. Carbimazole is metabolized to methimazole, which is responsible for the antithyroid activity.

    Categories: Heterocyclic Compounds, 1-RingSynonyms: Ethyl 3-methyl-2-thioimidazoline-1-carboxylate
  4. Drug

    Naratriptan

    go.drugbank.com/drugs/DB00952
    Approved

    Naratriptan is a triptan drug that is selective for the 5-hydroxytryptamine1 receptor subtype. It is typically used for the treatment of migraine headaches.

    Synonyms: N-methyl-2-(3-(1-methylpiperiden-4-yl)indole-5-yl)ethanesulfonamide, N-methyl-2-[3-(1-methyl-4-piperidyl)-1H-indol-5-yl]-ethanesulfonamideCategories: Monoamine Oxidase A Substrates, Heterocyclic Compounds, 1-Ring
  5. Drug

    Raltitrexed

    go.drugbank.com/drugs/DB00293
    ApprovedInvestigational

    Raltitrexed (brand name Tomudex®) is a chemotherapy drug manufactured AstraZeneca Company, is an antimetabolite used in chemotherapy. It is an inhibitor of thymidylate synthase.

    Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingProducts: TOMUDEX ® 2 MG, TOMUDEX 2 MG FLAKON, 1 ADET
  6. Drug

    Influenza B virus B/Brisbane/60/2008 hemagglutinin antigen (formaldehyde inactivated)

    go.drugbank.com/drugs/DB14385
    ApprovedInvestigationalWithdrawn

    A seasonally-specific component of the influenza vaccine. The influenza vaccine, also known as the "flu shot", is a vaccine that protects against infection from the influenza viruses. … Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed, or inactivated, through exposure to heat or chemicals such as formaldehyde 3.

    Mixtures: Fluarix 2010/2011Categories: Inactivated Influenza B Virus Vaccine
  7. Drug

    Factor IX Complex (Human)

    go.drugbank.com/drugs/DB11330
    ApprovedInvestigational

    Factor IX Complex is a sterile, lyophilized concentrate composed of a number of Vitamin K-dependent clotting factors found in functioning human plasma. … For example, Kcentra (FDA) also contains the antithrombotic proteins C and S, while Bebulin VH (FDA) contains heparin.

    Synonyms: Coagulation factor IX, II, VII and X in combinationProducts: BERIPLEX P/N 500 IU ENJEKSİYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN TOZ VE ÇÖZÜCÜ, 1 ADET, BERIPLEX P/N 250 IU ENJEKSİYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN TOZ VE ÇÖZÜCÜ, 1 ADET
  8. Indication

    Ankle spasticity following a stroke or traumatic brain injury

    go.drugbank.com/conditions/DBCOND0133858
    Drugs: Clostridium botulinum
    Synonyms: Ankle spasticity following a stroke or traumatic brain injury
  9. Target

    3-hydroxy-3-methylglutaryl-coenzyme A reductase

    go.drugbank.com/bio_entities/BE0000574
    TargetEnzymeHumans

    HMGCR is the main target of statins, a class of cholesterol-lowering drugs (PubMed:11349148, PubMed:18540668, PubMed:36745799) … Catalyzes the conversion of (3S)-hydroxy-3-methylglutaryl-CoA (HMG-CoA) to mevalonic acid, the rate-limiting step in the synthesis of cholesterol and other isoprenoids, thus plays a critical role in cellular

    Polypeptides: 3-hydroxy-3-methylglutaryl-coenzyme A reductaseFunction: coenzyme A binding
  10. Target

    Acetyl-coenzyme A synthetase 2-like, mitochondrial

    go.drugbank.com/bio_entities/BE0000746
    TargetHumans

    Involved in thermogenesis under ketogenic conditions, using acetate as a vital fuel when carbohydrate availability is insufficient (By similarity) … Can also utilize propionate with a much lower affinity (By similarity). Provides acetyl-CoA that is utilized mainly for oxidation under ketogenic conditions (By similarity).

    Polypeptides: Acetyl-coenzyme A synthetase 2-like, mitochondrial