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WU-CART-007
go.drugbank.com/drugs/DB18617InvestigationalWU-CART-007 consists of allogeneic, fratricide-resistant genetically modified T cells transduced with a 2nd generation 4-1BB-CD3z chimeric antigen receptor targeting human CD7.
Synonyms: an allogeneic, fratricide-resistant genetically modified T cell transduced with a 2nd generation 4-1BB-CD3z chimeric antigen receptor targeting human CD7Etryptamine
go.drugbank.com/drugs/DB01546ApprovedIllicitWithdrawnHowever, in 1962, after the discovery of an unacceptable incidence of agranulocytosis, the development of Monase was halted and the drug was withdrawn from potential market use. … αET is a stimulant and hallucinogen, but it is less stimulating and hallucinogenic than alpha-methyltryptamine, a closely related compound.
Reslizumab
go.drugbank.com/drugs/DB06602ApprovedInvestigationalBy targeting the IL-5 and disrupting its signalling pathways, reslizumab aims to inhibit eosinophil maturation and promote programmed cell death [A31578]. … Inflammation-predominant asthma, which is chatacterized by eosinophilic infiltration of airway mucosa and elevated levels of eosinophils in the blood, sputum and BAL fluid, is associated with an increased
Categories: Amino Acids, Peptides, and ProteinsAliskiren
go.drugbank.com/drugs/DB09026ApprovedInvestigational[A203624] It was developed by Speedel and Novartis and initially approved by the FDA in early 2007. … Aliskiren is the first drug in the renin inhibitor drug class and is used for the treatment of hypertension.
Categories: valsartan and aliskiren, aliskiren and amlodipineSodium oxybate
go.drugbank.com/drugs/DB09072ApprovedInvestigationalSodium oxybate has been misused to stimulate body growth and to induce euphoria, disinhibition, and sexual arousal as a "party drug" or "club drug." … [L30598] It is a sodium salt of [gamma-Hydroxybutyric acid], an endogenous cerebral inhibitory neurotransmitter [A251445] and a metabolite of the inhibitory neurotransmitter GABA.
Myelodysplastic Syndrome
go.drugbank.com/conditions/DBCOND0028333Synonyms: Classical Lissencephalies and Subcortical Band Heterotopias, (Neoplasm of uncert behav of other lymphat and haematopoietic tissue) or (neoplasm of uncert behav of blood) or (idiopathic thrombocythaemia) or (megakaryocytic myelosclerosis) or (myelodysplasia)Pregnancy Toxemias
go.drugbank.com/conditions/DBCOND0027911Synonyms: EPH - Edema, proteinuria and hypertension of pregnancy, EPH - Oedema, proteinuria and hypertension of pregnancyLactic acid
go.drugbank.com/drugs/DB04398ApprovedInvestigationalVet approvedThe concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed) Sodium lactate is the sodium salt of lactic acid, and has a mild saline taste. … It is produced by fermentation of a sugar source, such as corn or beets, and then, by neutralizing the resulting lactic acid to create a compound having the formula NaC3H5O3.
Mixtures: Ti-U-lac Lotion, Ionosol B and DextroseCategories: Basic Ointments and Protectants, Genito Urinary System and Sex HormonesDihydrocodeine
go.drugbank.com/drugs/DB01551ApprovedIllicitDihydrocodeine is an opioid analgesic used as an alternative or adjunct to codeine to treat moderate to severe pain, severe dyspnea, and cough. … It is semi-synthetic, and was developed in Germany in 1908 during an international search to find a more effective antitussive agent to help reduce the spread of airborne infectious diseases such as tuburculosis
Mixtures: dihydrocodeine bitartrate and aspirin and caffeine DC, Acetaminophen, Caffeine and Dihydrocodeine BitartrateCategories: dihydrocodeine and paracetamol, dihydrocodeine and acetylsalicylic acidFamtozinameran
go.drugbank.com/drugs/DB17088ApprovedInvestigational[L43922] The Omicron variant comprises several distinct lineages and sublineages (e.g. BA.4, BA.5) which, although similar, may behave differently from one another. … [L43922] It tends to cause less severe disease but is significantly more virulent than both the original virus and earlier variants (e.g. Delta).
Categories: Amino Acids, Peptides, and Proteins