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Displaying results 2481 - 2490 of 10000 in total
  1. Drug

    Tafenoquine

    go.drugbank.com/drugs/DB06608
    ApprovedInvestigational

    Tafenoquine is an 8-aminoquinoline analogue of primaquine which varies only on the presence of a 5-phenoxy group. … [A35690] Tafenoquine was further developed collaboratively between GlaxoSmithKline and Medicines for Malaria Venture.[A35677] It was FDA approved on July 20, 2018.[L3770]

    Categories: Antiparasitic Products, Insecticides and Repellents
  2. Drug

    Palonosetron

    go.drugbank.com/drugs/DB00377
    ApprovedInvestigational

    its class approved for this use by the U.S. … Palonosetron (INN, trade name Aloxi) is an antagonist of 5-HT3 receptors that is indicated for the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV).

    Categories: Alimentary Tract and Metabolism, Antiemetics and Antinauseants
  3. Drug

    Allogenic Donor CD362-enriched Human Umbilical Cord-derived Mesenchymal Stem Cells

    go.drugbank.com/drugs/DB15731
    Investigational

    These cells are CD362 enriched umbilical cord-derived mesenchymal stem cells (UC-MSCs); UC-MSCs share stemness markers with both embryonic stem cells (ESCs) and adult mesenchymal stem cells (MSCs); this … ORBCEL-C™ is the trade name of a product composed of highly purified stromal cells derived from the human umbilical cord.

  4. Drug

    Proline

    go.drugbank.com/drugs/DB00172
    ApprovedInvestigationalNutraceutical

    Proline is a non-essential amino acid that is synthesized from glutamic acid. It is an essential component of collagen and is important for proper functioning of joints and tendons. … Proline is sometimes called an imino acid, although the IUPAC definition of an imine requires a carbon-nitrogen double bond.

    Mixtures: Aminosyn II and Dextrose, Aminosyn II and DextroseCategories: Amino Acids, Peptides, and Proteins
  5. Indication

    Dermatophyte Infection

    go.drugbank.com/conditions/DBCOND0139636
    Drugs: Amorolfine · Beclomethasone dipropionate · Bifonazole · Boric acid · Chloroxine · Chlorquinaldol +15 more
    Synonyms: Dermatomycosis, other and unspecified
  6. Drug

    Sorafenib

    go.drugbank.com/drugs/DB00398
    ApprovedInvestigational

    [A255852] First approved by the FDA and European Commission in 2007 for the treatment of hepatocellular carcinoma, sorafenib is also indicated to treat renal carcinoma and differentiated thyroid carcinoma … Sorafenib is a bi-aryl urea and an oral multikinase inhibitor.

    Categories: Antineoplastic and Immunomodulating Agents
  7. Drug

    Magaldrate

    go.drugbank.com/drugs/DB08938
    ApprovedInvestigationalWithdrawn

    Magaldrate is an antacid drug used for the treatment of esophagitis, duodenal and gastric ulcers, and gastroesophageal reflux. Magaldrate has been discontinued in the US market.

    Categories: Alimentary Tract and Metabolism, magaldrate and antiflatulents
  8. Target

    Stabilin-2

    go.drugbank.com/bio_entities/BE0004948
    TargetHumans

    Binds to both Gram-positive and Gram-negative bacteria and may play a role in defense against bacterial infection. … The proteolytically processed 190 kDa form also functions as an endocytosis receptor for heparin internalization as well as HA and CS

    Synonyms: FAS1 EGF-like and X-link domain-containing adhesion molecule 2, Fasciclin, EGF-like, laminin-type EGF-like and link domain-containing scavenger receptor 2
  9. Drug

    Ixekizumab

    go.drugbank.com/drugs/DB11569
    ApprovedInvestigational

    Ixekizumab is a humanized immunoglobulin G subclass 4 (IgG4) monoclonal antibody (mAb) against interleukin-17A (IL-17A) and prevents it from interacting with the IL-17A receptor. … Ixekizumab is produced by recombinant DNA technology in a recombinant mammalian cell line and purified using standard technology for bioprocessing.

    Categories: Amino Acids, Peptides, and Proteins, Skin and Mucous Membrane AgentsProducts: Taltz 80mg solution for injection in pre-filled pen, Taltz 80mg solution for injection in pre-filled syringe
  10. Drug

    Crinecerfont

    go.drugbank.com/drugs/DB18518
    ApprovedInvestigational

    [A264818] The majority of the poor health outcomes in patients with CAH result from the inability to precisely titrate glucocorticoid dosages to both adequately replace the deficiency and sufficiently … [A264818] Standard therapy involves cortisol replacement, but typically requires supraphysiological glucocorticoid doses to lower both ACTH and adrenal androgens, resulting in chronic glucocorticoid overexposure