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Displaying results 241 - 250 of 2828 in total
  1. Target

    Zinc transporter SLC39A7

    go.drugbank.com/bio_entities/BE0009893
    TransporterHumans

    Transports Zn(2+) from the endoplasmic reticulum (ER)/Golgi apparatus to the cytosol, playing an essential role in the regulation of cytosolic zinc levels (PubMed:14525538, PubMed:15705588, PubMed:28205653

    Polypeptides: Zinc transporter SLC39A7Function: zinc ion transmembrane transporter activity
  2. Target

    Zinc transporter ZIP12

    go.drugbank.com/bio_entities/BE0009897
    TransporterHumans

    The transport activity is temperature dependent. May play a role in neurulation and neurite extension.

    Polypeptides: Zinc transporter ZIP12Synonyms: LIV-1 subfamily of ZIP zinc transporter 8
  3. Target

    Zinc transporter ZIP13

    go.drugbank.com/bio_entities/BE0009900
    TransporterHumans

    Functions as a zinc transporter transporting Zn(2+) from the Golgi apparatus to the cytosol and thus influences the zinc level at least in areas of the cytosol (PubMed:21917916, PubMed:23213233).

    Polypeptides: Zinc transporter ZIP13Synonyms: LIV-1 subfamily of ZIP zinc transporter 9
  4. Target

    Zinc transporter ZIP11

    go.drugbank.com/bio_entities/BE0009906
    TransporterHumans

    May transport copper ions as well. The transport mechanism remains to be elucidated

    Polypeptides: Zinc transporter ZIP11Function: copper ion transmembrane transporter activity
  5. Target

    Zinc transporter 6

    go.drugbank.com/bio_entities/BE0009907
    TransporterHumans

    Has probably no intrinsic transporter activity but together with SLC30A5 forms a functional zinc ion:proton antiporter heterodimer, mediating zinc entry into the lumen of organelles along the secretory

    Polypeptides: Zinc transporter 6Function: zinc ion transmembrane transporter activity
  6. Target

    Vesicular acetylcholine transporter

    go.drugbank.com/bio_entities/BE0015071
    TargetHumans

    Can transport serotonin

    Polypeptides: Vesicular acetylcholine transporterFunction: acetylcholine transmembrane transporter activity
  7. Drug

    Maralixibat

    go.drugbank.com/drugs/DB16226
    ApprovedInvestigational

    Maralixibat (also known as SHP625, LUM001, and lopixibat) is an ileal bile acid transporter inhibitor, like [odevixibat].

    Categories: Ileal bile acid transport inhibitor, Ileal Bile Acid Transporter Inhibitor
  8. Drug

    Stem bromelain

    go.drugbank.com/drugs/DB12249
    Approved

    Although both fruit and stem bromelain are prepared differently and contain different enzymatic compositions, the general term bromelain typically refers to stem bromelain [A27198]. … Bromelain itself belongs to a category of protein-digesting enzymes that are obtained commercially from the fruit or stem of pineapples [A27198].

    Synonyms: Bromelain, stem, Stem bromelain
  9. Drug

    Polyinosinic-polycytidylic acid

    go.drugbank.com/drugs/DB16467
    Investigational

    Synonyms: Polyinosinic-polycytidylic acid complex
  10. Drug

    Marnetegragene autotemcel

    go.drugbank.com/drugs/DB17595
    Approved

    [L56116, A275467] Marnetegragene autotemcel, also known as marne-cel, is an autologous hematopoietic stem cell-based gene therapy created from the patient's own hematopoietic stem cells. … [L56115, L56116] The gene therapy is lentiviral vector-based and contains patient-derived CD34+ hematopoietic stem cells transduced with a functional ITGB2 gene [L56115, L56116].

    Categories: Autologous Hematopoietic Stem Cell-Based Gene TherapySynonyms: Hematopoietic stem cells modified with a lentiviral vector containing the CD18 (integrin beta 2) gene