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Displaying results 241 - 250 of 10000 in total
  1. Drug

    Rivaroxaban

    go.drugbank.com/drugs/DB06228
    ApprovedInvestigational

    However there is no antidote available in the event of a major bleed. Only the 10 mg tablet can be taken without regard to food. The 15 mg and 20 mg tablet should be taken with food. … FDA approved on July 1, 2011.

    Products: RIVAROXABAN EG, RIVAROXABAN EG STADA
  2. Drug

    Icatibant

    go.drugbank.com/drugs/DB06196
    ApprovedInvestigational

    [A4017,A263041] It was investigated as a potential treatment of hereditary angioedema (HAE) as bradykinin was implicated in HAE swelling; specifically, mice lacking B<sub>2</sub> receptors showed reduced … [A4017,A263046] Icatibant was approved by the FDA on August 25, 2011, and by the EMA in 2008 as a treatment for hereditary angioedema.

    Categories: Drugs Used in Hereditary AngioedemaProducts: ICATIBANT EG, İCATİN 30MG/3ML ÇÖZELTİ İÇEREN KULLANIMA HAZIR ENJEKTÖR
  3. Drug

    Pravastatin

    go.drugbank.com/drugs/DB00175
    ApprovedInvestigational

    [T303] Pravastatin was firstly approved in 1991 becoming the second available statin in the United States. It was the first statin administered as the active form and not as a prodrug. … [L6142] Pravastatin is made through a fermentation process in which [mevastatin] is first obtained.

    Products: PRAVASTATINA EG, PRAVASTATIN HEU 10MG NET
  4. Drug

    Ezetimibe

    go.drugbank.com/drugs/DB00973
    ApprovedInvestigational

    [A33313] In genetically NPC1L1-deficient mice, a 70% reduction in intestinal cholesterol absorption was seen, and these mice were insensitive to ezetimibe treatment - it was determined based on these findings … The discovery and research of this drug began in the early 1990s, after the intravenous administration of radiolabelled ezetimibe in rats revealed that it was being localized within enterocytes of the

    Mixtures: ATOZET (10MG/10MG), ATOZET TABLET 10MG/10MGProducts: EZETIMIBE EG, Mac-Zet (Ezetimibe Tablets USP 10 mg)
  5. Pathway

    Acylcarnitine (5Z)-7-[(1S,5E)-5-[(2E)-oct-2-en-1-ylidene]-4-oxocyclopent-2-en-1-yl]hept-5-enoylcarnitine

    smpdb.ca/view/SMP0123550
    Metabolic

    membrane to once again form (5Z)-7-[(1S,5E)-5-[(2E)-oct-2-en-1-ylidene]-4-oxocyclopent-2-en-1-yl]hept-5-enoyl-CoA and L-carnitine. (5Z)-7-[(1S,5E)-5-[(2E)-oct-2-en-1-ylidene]-4-oxocyclopent-2-en-1-yl] … (5Z)-7-[(1S,5E)-5-[(2E)-oct-2-en-1-ylidene]-4-oxocyclopent-2-en-1-yl]hept-5-enoylcarnitine is an acylcarnitine.

    Drugs: Biotin · Adenosine phosphate · ATP · Levocarnitine · Magnesium cation · Pyrophosphoric acid +1 more
  6. Drug

    Cinacalcet

    go.drugbank.com/drugs/DB01012
    ApprovedInvestigational

    It is used to treat hyperparathyroidism due to parathyroid tumours or renal failure. … Cinacalcet is a calcimimetic sold by Amgen under the trade name Sensipar® in North America and Australia and as Mimpara® in Europe.

    Synonyms: (R)-α-methyl-N-[3-[3-(trifluoromethyl)phenyl]propyl]-1-naphthalenemethane amine, N-((1R)-1-(Naphthalen-1-yl)ethyl)-3-(3-(trifluoromethyl)phenyl)propan-1-amineProducts: CINACALCET EG, TICAGRELOR EG
  7. Drug

    Tamoxifen

    go.drugbank.com/drugs/DB00675
    ApprovedInvestigational

    [A1025,L7799,L7802] Tamoxifen is used alone or as an adjuvant in these treatments. … [A1026] Tamoxifen was granted FDA approval on 30 December 1977.[L7799]

    Synonyms: 1-p-beta-Dimethylaminoethoxyphenyl-trans-1,2-diphenylbut-1-ene, (Z)-2-(4-(1,2-Diphenyl-1-butenyl)phenoxy)-N,N-dimethylethanamineProducts: TAMOXIFENE EG, Tamone Tab 10mg
  8. Drug

    Pergolide

    go.drugbank.com/drugs/DB01186
    ApprovedVet approvedWithdrawn

    It is an ergot derivative that acts on the dopamine D2 and D3, alpha2- and alpha1-adrenergic, and 5-hydroxytryptamine (5-HT) receptors. … It was indicated as adjunct therapy with levodopa/carbidopa in the symptomatic treatment of parkinsonian syndrome. It was later found that pergolide increased the risk of cardiac valvulopathy.

    Products: PERGOLIDE EG, Permax Tab 1mg
  9. Drug

    Yohimbine

    go.drugbank.com/drugs/DB01392
    ApprovedInvestigationalVet approvedWithdrawn

    Yohimbine has been used as a mydriatic and in the treatment of impotence. It is also alleged to be an aphrodisiac.

    Categories: Drugs Used in Erectile DysfunctionProducts: Yohimbine Tab 6mg, Yohimbine-odan 6mg
  10. Drug

    Mianserin

    go.drugbank.com/drugs/DB06148
    ApprovedWithdrawn

    Mianserin was previously available internationally, however in most markets it has been phased out in favour of [mirtazapine].

    Products: MIANSERIN 10MG HOLSTEN, MIANSERIN-REMEDICA 10mg Film-Coated Tablets