Search
Lamotrigine
go.drugbank.com/drugs/DB00555ApprovedInvestigationalLamotrigine is an antiepileptic drug belonging in the phenyltriazine class. It is used in the treatment of both epilepsy and as a mood stabilizer in bipolar disorder. … Lamotrigine is the first medication since lithium granted Food and Drug Administration (FDA) approval for the maintenance treatment of bipolar type I. It is approved for use in more than 30 countries.
Synonyms: 3,5-diamino-6-(2,3-dichlorophenyl)-1,2,4-triazineInternational brands: Lameptil SDextromethorphan
go.drugbank.com/drugs/DB00514ApprovedInvestigational[A215412] Although similar in structure to other opioids, it has minimal interaction with opioid receptors.[A215412] Dextromethorphan was granted FDA approval before 3 December 1957. … Dextromethorphan is a levorphanol derivative and codeine analog commonly used as a cough suppressant and also a drug of abuse.
Mixtures: BENICAL 10 MG+20MG+2MG/5 ML SURUP, 100 ML, Poly-Vent DMCategories: Uncompetitive N-methyl-D-aspartate Receptor Antagonist, Sigma-1 AgonistPrasugrel
go.drugbank.com/drugs/DB06209ApprovedInvestigationalSimilar to clopidogrel, prasugrel is a prodrug that requires enzymatic transformation in the liver to its active metabolite, R-138727. … R-138727 irreversibly binds to P2Y12 type ADP receptors on platelets thus preventing activation of the GPIIb/IIIa receptor complex.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2B6 SubstratesProducts: PRASUGREL BETA 5 MG FTA, Prasulan 5 mg-FilmtablettenRuxolitinib
go.drugbank.com/drugs/DB08877ApprovedInvestigationalRuxolitinib, formerly known as INCB018424 or INC424, is an anticancer drug and a Janus kinase (JAK) inhibitor. … It is a potent and selective inhibitor of JAK1 and JAK2,[A229698] which are tyrosine kinases involved in cytokine signalling and hematopoiesis.
Categories: Cytochrome P-450 CYP2C9 Substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic IndexProducts: JAKAVI 5 MG (TABLETS), JAKAVI 5 MG TABLET, 56 TABLETPotassium citrate
go.drugbank.com/drugs/DB09125ApprovedInvestigationalVet approvedIn the monohydrate form it is highly hygroscopic and deliquescent. Potassium citrate is used to treat a kidney stone condition called renal tubular acidosis. … Potassium citrate (also known as tripotassium citrate) is a potassium salt of citric acid. It is a white, hygroscopic crystalline powder. It is odorless with a saline taste.
Mixtures: PEDIALYTE®30MEQ CON ZN, Calcium-magnesium With K & Zn and Vitamin D3Products: CITRAL SYRUP (PLAIN) 500 mg/5 ml, UROCIT-K(5 MEQ) 540 MG 100 KONTROLLU SALIM TABLETINimesulide
go.drugbank.com/drugs/DB04743ApprovedWithdrawnNimesulide is a relatively COX-2 selective, non-steroidal anti-inflammatory drug (NSAID) with analgesic and antipyretic properties. … Due to concerns about the risk of hepatotoxicity, nimesulide has been withdrawn from market in many countries.
Mixtures: ETNA COMBO 100 MG/8 MG TABLET, 14 ADET, NİMES COMBO 100 MG / 8 MG TABLET , 14 ADETCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesNandrolone decanoate
go.drugbank.com/drugs/DB08804ApprovedIllicitInvestigational[A233849] Nandrolone decanoate was granted FDA approval on 5 October 1962.[L32564] … [A233789,A233849,L32564,L9464] The process for creating esters of [nandrolone] was patented in Spain in 1959[L33244] and in 1960, it was described as having a long duration of action and strong anabolic
Categories: Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substratesProducts: PARABOLIN RETARD 5 MG AMPUL, 2 ADET, DECA - DURABOLIN® 50 MGRasburicase
go.drugbank.com/drugs/DB00049ApprovedInvestigationalRasburicase is a recombinant urate-oxidase enzyme produced by a genetically modified <i>Saccharomyces cerevisiae</i> strain. … The cDNA coding for rasburicase was cloned from a strain of _Aspergillus flavus_.
Products: FASTURTEC 7,5 MG/5 ML INFIZYONLUK COZELTI ICIN TOZ VE COZUCU, 1ADET, FASTURTEC®1.5 MG / MLCarbimazole
go.drugbank.com/drugs/DB00389ApprovedAn imidazole antithyroid agent. Carbimazole is metabolized to methimazole, which is responsible for the antithyroid activity.
Synonyms: Ethyl 3-methyl-2-thioimidazoline-1-carboxylateCategories: Heterocyclic Compounds, 1-RingAntilymphocyte immunoglobulin (horse)
go.drugbank.com/drugs/DB09312ApprovedInvestigationalInduction of T cell apoptosis and resulting T-cell lymphopenia found in vivo is credited for its therapeutic effect in these conditions. … It is formed by inoculating a horse with an antigen (human thymoyctes) which then induces the horse immune system's B-lymphocytes to produce IgG immunoglobulins specific for that antigen.
Synonyms: e-ATG, h-ATGCategories: Immunoglobulin G, Increased T Lymphocyte Destruction