Search

Displaying results 2551 - 2560 of 10000 in total
  1. Drug

    UCB7362

    go.drugbank.com/drugs/DB17096
    Experimental

    It has shown high potency in biochemical (IC<sub>50</sub> = 7 nM), _in vitro_ (_P. falciparum_ 3D7 lactate dehydrogenase growth inhibition assay IC<sub>50</sub> = 10 nM), and _in vivo_ (50 mg/kg dose … [A254222] Plasmepsins are aspartyl proteases produced by the malaria parasite _Plasmodium falciparum_, and PMX is considered to be essential for parasite egress and invasion.

  2. Drug

    Enasidenib

    go.drugbank.com/drugs/DB13874
    ApprovedInvestigational

    First developed by Agios Pharmaceuticals and licensed to Celgene, enasidenib was approved by U.S. Food and Drug Administration on August 1, 2017. … This small molecule acts as an allosteric inhibitor of mutant IDH2 enzyme to prevent cell growth, and it also has shown to block several other enzymes that play a role in abnormal cell differentiation.

    Categories: Cytochrome P-450 CYP1A2 Inhibitors, Cytochrome P-450 Substrates
  3. Drug

    Elvitegravir

    go.drugbank.com/drugs/DB09101
    ApprovedInvestigational

    Elvitegravir was first licensed from Japan Tobacco in 2008 and developed by Gilead Sciences. It was FDA approved on August 27, 2012.

    Mixtures: GENVOYA FILM COATED TABLET 150 MG/150 MG/200 MG/10 MG, STRIBILD FILM COATED TABLET 150 MG/150 MG/200 MG/245 MGCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C9 Inducers
  4. Drug

    Sitafloxacin

    go.drugbank.com/drugs/DB13261
    Investigational

    Categories: Cytochrome P-450 CYP1A2 Inhibitors, Cytochrome P-450 Enzyme InhibitorsProducts: เกรซวิท เม็ด 50
  5. Drug

    Lonapegsomatropin

    go.drugbank.com/drugs/DB16220
    ApprovedInvestigational

    , with growth failure due to insufficient growth hormone secretion. … Lonapegsomatropin, also known as TransCon hGH or ACP 001, is a methoxypegylated prodrug of human growth hormone ([somatropin]) indicated for the treatment of children 1 year and older, weighing at least 11.5 kg

    Categories: Cytochrome P-450 CYP1A2 Inducers, Cytochrome P-450 Enzyme Inducers
  6. Drug

    Taurine

    go.drugbank.com/drugs/DB01956
    ApprovedInvestigationalNutraceutical

    [A31396] This conditional amino acid can be either be manufactured by the body or obtained in the diet mainly by the consumption of fish and meat. … [L1058] The supplements containing taurine were FDA approved by 1984 and they are hypertonic injections composed by cristalline amino acids.[FDA label]

    Mixtures: PEDASEL %10 AMİNO ASİT ÇÖZELTİSİ, 100 ML, PRIMENE %10 İNFÜZYONLUK PEDİYATRİK AMİNOASİT ÇÖZELTİSİ, 100 ML
  7. Indication

    Hyperthyroidism caused by Amiodarone

    go.drugbank.com/conditions/DBCOND0138882
    Drugs: Sodium perchlorate
    Synonyms: Hyperthyroidism secondary to amiodarone (disorder)
  8. Indication

    Pityriasis versicolor

    go.drugbank.com/conditions/DBCOND0021492
    Drugs: Amorolfine · Butenafine · Ciclopirox · Clotrimazole · Econazole · Fenticonazole +7 more
    Synonyms: Tinea versicolor due to Malassezia furfur, Tinea versicolor due to Pityrosporum furfur
  9. Indication

    Hyperthermia, Anesthesia Related

    go.drugbank.com/conditions/DBCOND0150383
    Drugs: Dantrolene
    Synonyms: Malignant hyperthermia due to anesthesia, Malignant hyperpyrexia due to anesthesia
  10. Drug

    Acetic acid

    go.drugbank.com/drugs/DB03166
    ApprovedInvestigational

    (Stedman, 26th ed) Acetic acid otic (for the ear) is an antibiotic that treats infections caused by bacteria or fungus.

    Mixtures: Selectbag One (ax 150 G), AMINOSTERIL N-HEPA 500 ML SOLUSYON