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Displaying results 2551 - 2560 of 10000 in total
  1. Drug

    Sacubitril

    go.drugbank.com/drugs/DB09292
    ApprovedInvestigational

    Inhibition of neprilysin therefore leads to reduced breakdown and increased concentration of endogenous natriuretic peptides in addition to increased levels of vasoconstricting hormones such as angiotensin … It was approved by the FDA after being given the status of priority review for on July 7, 2015.

    Mixtures: ENTRESTO 100 MG, ENTRESTO 100 MG
  2. Drug

    Lonapegsomatropin

    go.drugbank.com/drugs/DB16220
    ApprovedInvestigational

    , with growth failure due to insufficient growth hormone secretion. … Lonapegsomatropin, also known as TransCon hGH or ACP 001, is a methoxypegylated prodrug of human growth hormone ([somatropin]) indicated for the treatment of children 1 year and older, weighing at least 11.5 kg

    Categories: Cytochrome P-450 CYP1A2 Inducers, Cytochrome P-450 Enzyme Inducers
  3. Indication

    Hyperthyroidism caused by Amiodarone

    go.drugbank.com/conditions/DBCOND0138882
    Drugs: Sodium perchlorate
    Synonyms: Hyperthyroidism secondary to amiodarone (disorder)
  4. Drug

    N-[[2-METHYL-4-HYDROXYCARBAMOYL]BUT-4-YL-N]-BENZYL-P-[PHENYL]-P-[METHYL]PHOSPHINAMID

    go.drugbank.com/drugs/DB08507
    Experimental

    Synonyms: N-[[2-METHYL-4-HYDROXYCARBAMOYL]BUT-4-YL-N]-BENZYL-P-[PHENYL]-P-[METHYL]PHOSPHINAMID
  5. Indication

    Pityriasis versicolor

    go.drugbank.com/conditions/DBCOND0021492
    Drugs: Amorolfine · Butenafine · Ciclopirox · Clotrimazole · Econazole · Fenticonazole +7 more
    Synonyms: Tinea versicolor due to Malassezia furfur, Tinea versicolor due to Pityrosporum furfur
  6. Drug

    Enasidenib

    go.drugbank.com/drugs/DB13874
    ApprovedInvestigational

    First developed by Agios Pharmaceuticals and licensed to Celgene, enasidenib was approved by U.S. Food and Drug Administration on August 1, 2017. … This small molecule acts as an allosteric inhibitor of mutant IDH2 enzyme to prevent cell growth, and it also has shown to block several other enzymes that play a role in abnormal cell differentiation.

    Categories: Cytochrome P-450 CYP1A2 Inhibitors, Cytochrome P-450 Substrates
  7. Drug

    Serine

    go.drugbank.com/drugs/DB00133
    ApprovedInvestigationalNutraceutical

    A non-essential amino acid occurring in natural form as the L-isomer. It is synthesized from glycine or threonine. It is involved in the biosynthesis of purines; pyrimidines; and other amino acids.

    Mixtures: PEDASEL %10 AMİNO ASİT ÇÖZELTİSİ, 100 ML, PRIMENE %10 İNFÜZYONLUK PEDİYATRİK AMİNOASİT ÇÖZELTİSİ, 100 ML
  8. Indication

    Hyperthermia, Anesthesia Related

    go.drugbank.com/conditions/DBCOND0150383
    Drugs: Dantrolene
    Synonyms: Malignant hyperthermia due to anesthesia, Malignant hyperpyrexia due to anesthesia
  9. Drug

    Novolimus

    go.drugbank.com/drugs/DB19085
    Investigational

    Novolimus is under investigation in clinical trial NCT04483791 (Dynamx Bioadaptor Hong Kong Registry).

    Synonyms: 16-o-demethylrapamycin, 16-o-demethylsirolimus
  10. Indication

    Food Allergy

    go.drugbank.com/conditions/DBCOND0031829
    Drugs: Chlorpheniramine · Cromoglicic acid · Guaifenesin
    Synonyms: Allergy to food (finding), Gastrointestinal allergy to food (finding)