Search

Displaying results 2591 - 2600 of 10000 in total
  1. Pathway

    Fluorouracil Metabolism

    smpdb.ca/view/SMP0121111
    Metabolic

    Tegafur is another prodrug that may be converted to fluorouracil, this time by cytochrome P450 2A6 in the endoplasmic reticulum membrane. … It may stop there, or be converted back to 5-fluorodeoxyuridine monophosphate by deoxyuridine 5'-triphosphate nucleotidohydrolase, also in the mitochondria.

    Drugs: ATP · Floxuridine · Fluorouracil · Capecitabine · Magnesium cation · Zinc +6 more
  2. Drug

    Nitrofurantoin

    go.drugbank.com/drugs/DB00698
    ApprovedInvestigationalVet approved

    [A179824] Nitrofurantoin is a second line treatment to [trimethoprim]/[sulfamethoxazole].[A179830] Nitrofurantoin was granted FDA approval on 6 February 1953.[L6895] … [A179824] This drug is more resistant to the development of bacterial resistance because it acts on many targets at once.

    Categories: P-glycoprotein substrates, Heterocyclic Compounds, 1-RingSynonyms: N-(5-Nitrofurfurylidene)-1-aminohydantoin, 1-((5-nitro-2-furanyl)methylene)amino-2,4-imidazolidenedione
  3. Drug

    Efavirenz

    go.drugbank.com/drugs/DB00625
    ApprovedInvestigational

    Efavirenz is also used in combination with other antiretroviral agents as part of an expanded postexposure prophylaxis regimen to prevent HIV transmission for those exposed to materials associated with … For HIV infection that has not previously been treated, efavirenz and lamivudine in combination with zidovudine or tenofovir is the preferred NNRTI-based regimen.

    Mixtures: Symfi Lo, TOLAK ®3 TABLETAS RECUBIERTASCategories: Antivirals used in combination for the treatment of HIV infections, Inducers of Drug Clearance
  4. Drug

    Acamprosate

    go.drugbank.com/drugs/DB00659
    ApprovedInvestigational

    It is a structural analogue of the neurotransmitter γ-aminobutyric acid (GABA). … It was first approved by the FDA in 2004 and initially marketed by Forest Laboratories.[L31783]

    Categories: Drugs Used in Addictive Disorders, Drugs Used in Alcohol DependenceSynonyms: N-Acetylhomotaurine, N-acetyl homotaurine
  5. Drug

    Regadenoson

    go.drugbank.com/drugs/DB06213
    ApprovedInvestigational

    Regadenoson is an A2A adenosine receptor agonist that causes coronary vasodilation and used for myocardial perfusion imagining. Manufactured by Astellas and FDA approved April 10, 2008.

    Categories: Adenosine A receptor agonists, Heterocyclic Compounds, 1-RingProducts: Lexiscan(r) (regadenoson)
  6. Drug

    Lanthanum carbonate

    go.drugbank.com/drugs/DB06792
    Approved

    It is used to treat elevated phosphate levels, primarily in patients with chronic kidney disease, by binding to dietary phosphate and preventing its absorption in the intestine.[L50733] … It is a large pill that requires thorough chewing to avoid choking and other gastrointestinal adverse effects.

    Categories: Drugs for Treatment of Hyperkalemia and HyperphosphatemiaSynonyms: Lanthanum(3+) carbonate
  7. Drug

    Obiltoxaximab

    go.drugbank.com/drugs/DB05336
    Approved

    Obiltoxaximab is a chimeric IgG1 kappa monoclonal antibody (mAb) that binds the PA component of B. anthracis toxin. It has an approximate molecular weight of 148 kDa. … Obiltoxaximab, an affinity-enhanced monoclonal antibody (Mab), is used for prevention and treatment of infection and death caused by anthrax toxin.

  8. Drug

    Diphenylpyraline

    go.drugbank.com/drugs/DB01146
    Approved

    Diphenylpyraline is an antihistamine. Antihistamines used in the treatment of allergy act by competing with histamine for H 1-receptor sites on effector cells. … Antihistamines prevent, but do not reverse, responses mediated by histamine alone.

    Mixtures: Emercidin D Tab, Biohisdex DM DecongestantCategories: Heterocyclic Compounds, 1-Ring
  9. Drug

    Bordetella pertussis toxoid antigen (formaldehyde inactivated)

    go.drugbank.com/drugs/DB14388
    ApprovedInvestigational

    Bordetella pertussis toxoid antigen (formaldehyde inactivated) is a vaccine.

    Mixtures: -POLIO SUSPENSION FOR INJECTION IN PRE-FILLED SYRINGE, Repevax Injektionssuspension in einer FertigspritzeSynonyms: Bordetella Pertussis Toxoid Antigen, C
  10. Drug

    Calcium levulinate

    go.drugbank.com/drugs/DB13800
    Approved

    The resultant calcium levulinate formulation, when used as a calcium supplement, possesses a high calcium content that is observed to be 14.8% higher than the content typically found in calcium lactate … The relatively new calcium levulinate is produced from a direct reaction between L- or levulinic acid levulose and calcium hydroxide [L2765].

    Mixtures: Calcium Inj, CALCIUM PICKEN %10 ENJEKSİYONLUK ÇÖZELTİ AMPUL, 5 ADET