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Displaying results 2601 - 2610 of 10000 in total
  1. Drug

    Daleuton

    go.drugbank.com/drugs/DB00154
    InvestigationalNutraceutical

    A 20-carbon-chain fatty acid, unsaturated at positions 8, 11, and 14. It differs from arachidonic acid, 5,8,11,14-eicosatetraenoic acid, only at position 5.

    Synonyms: 20:3, n-6,9,12 all-cis, C20:3, n-6,9,12 all-cis
  2. Drug

    Anthralin

    go.drugbank.com/drugs/DB11157
    Approved

    Anthralin (1,8‐dihydroxy‐9anthrone, dithranol) is an older anti-psoriatic agent that was first synthesized as a derivative of chrysarobin, obtained from the araroba tree in Brazil over 100 years ago. … It is important to consider that the drug is relatively innocuous, yet effective, and systemic side effects have not been observed with this anthralin, in contrast to a wide variety of systemic and topical

    Mixtures: PSORAKS 30 GR KREM, PSORAKS 30 GR FORT KREM
  3. Drug

    Exagamglogene autotemcel

    go.drugbank.com/drugs/DB15572
    ApprovedInvestigational

    [L49231] It is the first CRISPR-based gene editing therapy to be approved in the United States. … [L10139] Following engraftment, it causes an increase in the production of HbF and a subsequent decrease in HbS.

  4. Drug

    Neon

    go.drugbank.com/drugs/DB11589
    Approved

    Neon is a chemical element with a chemical symbol Ne and atomic number 10. It is a noble gas that is colorless, odorless, inert and monatomic. … It is the fifth most abundant chemical element in the universe by mass but a rare element on Earth.

  5. Drug

    Bismuth subgallate

    go.drugbank.com/drugs/DB13909
    Approved

    internal deodorant where it is often employed as the primary active ingredient. … It is a heavy metal salt of gallic acid that is highly insoluble and poorly absorbed.

    Mixtures: KORTOS KREM, 30 G, HEMORALGINE 40 GR POMAD
  6. Drug

    Difelikefalin

    go.drugbank.com/drugs/DB11938
    ApprovedInvestigational

    Pruritus associated with chronic kidney disease (also called uremic pruritus) affects 50-60% of all patients on dialysis and 25% of non-dialysis patients with chronic kidney disease. … [A237610] Further investigations revealed that dynorphins, endogenous agonists of KORs, work to inhibit the itching sensation at the spinal cord level, and scratching could be elicited in mouse models

  7. Drug

    AG-858

    go.drugbank.com/drugs/DB05502
    Investigational

    AG-858 (autologous heat-shock protein 70 peptide vaccine) is a recombinant cancer vaccine made with tumor-derived heat shock protein 70 (HSP70) peptide complexes. … Tumor-derived HSP70-peptide complexes used in vaccine preparations have been shown to prime tumor immunity and tumor-specific T cells in animal models.

  8. Indication

    Vitamin B12 Deficiency

    go.drugbank.com/conditions/DBCOND0034596
    Drugs: Cobamamide · Cyanocobalamin · Fursultiamine · Hydroxocobalamin · Mecobalamin · Menadione +2 more
    Synonyms: Vitamin B-12 Deficiency, Vitamin B 12 Deficiency
  9. Drug

    Navtemadlin

    go.drugbank.com/drugs/DB15299
    Investigational

    Navtemadlin (AMG-232) is under investigation in clinical trial NCT03041688 (MDM2 Inhibitor AMG-232 and Decitabine in Treating Patients With Relapsed, Refractory, or Newly-Diagnosed Acute Myeloid Leukemia

    Synonyms: {(3R,5R,6S)-5-(3-chlorophenyl)-6-(4-chlorophenyl)-3-methyl-1-[ (2S)-3 -methyl-1-(propan-2- ylsulfonyl)butan-2-yl]-2-oxopiperidin-3-yl}acetic acid
  10. Drug

    Elafibranor

    go.drugbank.com/drugs/DB05187
    ApprovedInvestigational

    [L50768] On June 10, 2024, elafibranor was granted accelerated approval by the FDA for the treatment of primary biliary cholangitis (PBC).