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Displaying results 2601 - 2610 of 2872 in total
  1. Drug

    Limnetrelvir

    go.drugbank.com/drugs/DB21677
    Experimental

    Limnetrelvir is a small molecule drug. The usage of the INN stem '-trelvir' in the name indicates that Limnetrelvir is a antiviral 3CL protease inhibitor. Limnetrelvir has a monoisotopic molecular weight of 557.17 Da.

    Categories: Cytochrome P-450 CYP3A Inhibitors, Cytochrome P-450 Substrates
  2. Drug

    Sorbitan monolaurate

    go.drugbank.com/drugs/DB20157
    Investigational

    Sorbitan monolaurate is a small molecule drug. Sorbitan monolaurate has a monoisotopic molecular weight of 346.24 Da.

    Categories: P-glycoprotein inhibitors
  3. Drug

    Enerisant

    go.drugbank.com/drugs/DB20605
    Experimental

    Enerisant is a small molecule drug. The usage of the INN stem '-isant' in the name indicates that Enerisant is a histamine H3​ receptor antagonist. Enerisant has a monoisotopic molecular weight of 398.23 Da.

    Categories: P-glycoprotein substrates
  4. Drug

    Besigomsin

    go.drugbank.com/drugs/DB20894
    Experimental

    Besigomsin is a small molecule drug. Besigomsin has a monoisotopic molecular weight of 416.18 Da.

    Categories: P-glycoprotein inhibitors, Cytochrome P-450 Substrates
  5. Drug

    Fluorometholone

    go.drugbank.com/drugs/DB00324
    ApprovedInvestigational

    A glucocorticoid employed, usually as eye drops, in the treatment of allergic and inflammatory conditions of the eye. It has also been used topically in the treatment of various skin disorders. (From Martindale, The Extra Pharmacopoeia, ...

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Inducers
  6. Drug

    Terfenadine

    go.drugbank.com/drugs/DB00342
    ApprovedWithdrawn

    In the U.S., Terfenadine was superseded by fexofenadine in the 1990s due to the risk of cardiac arrhythmia caused by QT interval prolongation.

    Categories: P-glycoprotein inhibitors, P-glycoprotein substrates
  7. Drug

    Sulfadiazine

    go.drugbank.com/drugs/DB00359
    ApprovedInvestigationalVet approved

    One of the short-acting sulfonamides used in combination with pyrimethamine to treat toxoplasmosis in patients with acquired immunodeficiency syndrome and in newborns with congenital infections.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C8 Substrates
  8. Drug

    Vinorelbine

    go.drugbank.com/drugs/DB00361
    ApprovedInvestigational

    Vinorelbine is an anti-mitotic chemotherapy drug that is used in the treatment of several types of malignancies, including breast cancer and non-small cell lung cancer (NSCLC) . It was initially approved in the USA in 1990's for the trea...

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 Inhibitors
  9. Drug

    Grepafloxacin

    go.drugbank.com/drugs/DB00365
    ApprovedWithdrawn

    Grepafloxacin is an oral broad-spectrum quinoline antibacterial agent used to treat bacterial infections. Due to the QTc-prolonging potential, as indicated by the changes in the QT interval on the electrocardiogram, and the risk for card...

    Categories: P-glycoprotein inhibitors, P-glycoprotein substrates
  10. Drug

    Palonosetron

    go.drugbank.com/drugs/DB00377
    ApprovedInvestigational

    Palonosetron (INN, trade name Aloxi) is an antagonist of 5-HT3 receptors that is indicated for the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV). It is the most effective of the 5-HT3 antagonists in controll...

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates