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NF-kappa-B inhibitor alpha
go.drugbank.com/bio_entities/BE0003469TargetHumansInhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL (RELA/p65 and NFKB1/p50) dimers in the cytoplasm by masking their nuclear localization signals (PubMed:1493333, PubMed:36651806, PubMed:7479976). On cellular stimu...
Synonyms: Major histocompatibility complex enhancer-binding protein MAD3Hydromorphone
go.drugbank.com/drugs/DB00327ApprovedIllicitInvestigationalStructurally, hydromorphone derived from [morphine] in the modification of the hydroxyl group in the carbon 6 to a carbonyl and the absence of a double bond between the carbon 7 and 8. … [A176495] The first reported approved product containing hydromorphone in the form of hydromorphone hydrochloride was developed by Fresenius Kabi USA and FDA approved in 1984.[L5795]
Products: HYDROMORPHON 1A 2MG, HYDROMORPHON 1A 4MGClove oil
go.drugbank.com/drugs/DB11338ApprovedNutraceuticalTraditionally, it has been used as a flavouring spice in foods, or as a fragrance. It is also found in topical analgesics. Clove oil has shown to exert some antimicrobial activities. … The FDA categorizes clove oil as generally recognized as safe (GRAS) for use in dental cement or as a food additive [F108].
Categories: Complex MixturesPotassium perchlorate
go.drugbank.com/drugs/DB09418ApprovedWithdrawnPotassium perchlorate is an inorganic salt with the chemical formula KClO4. It is a strong oxidizer with the lowest solubility of the alkali metal perchlorates. … The therapeutic use of potassium perchlorate in thyroid disorders has been ceased due to a high risk for developing aplastic anemia and nephrotic syndrome [L2364].
Carob
go.drugbank.com/drugs/DB10852ApprovedCarob allergenic extract is used in allergenic testing.
Categories: Compounds used in a research, industrial, or household setting, Complex MixturesLevocarnitine
go.drugbank.com/drugs/DB00583ApprovedInvestigationalIt is used therapeutically to stimulate gastric and pancreatic secretions and in the treatment of hyperlipoproteinemias.
Mixtures: Q 10 Suprabio +L-CarnitineSynonyms: L-Carnitine, (-)-L-CarnitineCocoa butter
go.drugbank.com/drugs/DB11086ApprovedStill, it is a common active ingredient for prevention of skin dryness in cosmetic and skincare products. … While cocoa butter has skin moisturizing properties, it was not shown to reduce the likelihood of developing of striae gravidarum, or stretch marks, in a double-blind, randomized clinical trial of women
Products: Coconut Cosmetics 3-in-1 SerumNADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6
go.drugbank.com/bio_entities/BE0000213TargetHumansRequired for proper complex I assembly (PubMed:30245030). Complex I functions in the transfer of electrons from NADH to the respiratory chain. … Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed to be not involved in catalysis.
Synonyms: Complex I-B14NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9
go.drugbank.com/bio_entities/BE0000596TargetHumansAccessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed to be not involved in catalysis. … Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone
Synonyms: Complex I-B22Proteasome subunit alpha type-5
go.drugbank.com/bio_entities/BE0003914TargetHumansComponent of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. … This type of proteolysis is required in several pathways including spermatogenesis (20S-PA200 complex) or generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex)
Synonyms: Multicatalytic endopeptidase complex zeta chain