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Fluorouracil
go.drugbank.com/drugs/DB00544ApprovedInvestigationalIt interferes with DNA synthesis by blocking the thymidylate synthetase conversion of deoxyuridylic acid to thymidylic acid.
Pinaverium
go.drugbank.com/drugs/DB09090ApprovedInvestigationalIt is shown to relieve GI spasm and pain, transit disturbances and other symptoms related to motility disorders [A19697] and may be considered as effective first-lline therapy for patients with irritable … It is a quaternary ammonium compound that acts as an atypical calcium antagonist to restore normal bowel function.
Gastric intrinsic factor
go.drugbank.com/drugs/DB09349Approvedis currently in the marketed (but unapproved) product Hematogen in combination with cyanocobalamin (synthetic Vitamin B12), ferrous fumarate, and ascorbic acid for the treatment of anemias responsive to
Proxibarbal
go.drugbank.com/drugs/DB13253ApprovedProxibarbal is a derivative of barbiturates, which has been used to treat migraines. … Proxibarbal was approved in France but was withdrawn from the market due to the risk of inducing immunoallergic thrombocytopenia [L5476].
Chenopodium album pollen
go.drugbank.com/drugs/DB10368ApprovedChenopodium album pollen is the pollen of the Chenopodium album plant. Chenopodium album pollen is mainly used in allergenic testing.
Mixtures: Number Two Weed MixtureInterferon alfa-n3
go.drugbank.com/drugs/DB00018ApprovedPurified, natural (n is for natural) human interferon alpha proteins (consists of 3 forms or polymorphisms including 2a, 2b and 2c). 166 residues, some are glycosylated (MW range from 16 kD to 27 kD).
Salmon calcitonin
go.drugbank.com/drugs/DB00017ApprovedInvestigationalSynthetic peptide, 32 residues long formulated as a nasal spray.
Paliperidone
go.drugbank.com/drugs/DB01267ApprovedInvestigationalThe mechanism of action is unknown but it is likely to act via a similar pathway to risperidone.
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeDicyclomine
go.drugbank.com/drugs/DB00804ApprovedInvestigational[A6556,A182555,A234659,L7967] Though it is commonly prescribed, its recommendation may have been based on a small amount of evidence and so its prescription is becoming less favourable. … Dicyclomine is a muscarinic M1, M3, and M2 receptor antagonist as well as a non-competitive inhibitor of histamine and bradykinin used to treat spasms of the intestines seen in functional bowel disorder
Pipotiazine
go.drugbank.com/drugs/DB01621ApprovedInvestigationalWithdrawnPipotiazine has actions similar to those of other phenothiazines. … Among the different phenothiazine derivatives, it appears to be less sedating and to have a weak propensity for causing hypotension or potentiating the effects of CNS depressants and anesthetics.