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Citalopram
go.drugbank.com/drugs/DB00215ApprovedInvestigationalIt is a racemic bicyclic phthalate derivate and is the only compound with a tertiary amine and 2 nitrogen-containing metabolites among all SSRIs. … [A261316] Citalopram was approved by the FDA in 1998 for the treatment of depression in adults 18 years or older.[L5230]
Products: CITREX 40 MG/ML 15 ML ORAL DAMLA, CITALOPRAM AL 10MG FILMTABSucrose
go.drugbank.com/drugs/DB02772ApprovedInvestigationalIt is obtained commercially from sugarcane, sugar beet (beta vulgaris), and other plants and used extensively as a food and a sweetener.
Categories: Compounds used in a research, industrial, or household settingChloric acid
go.drugbank.com/drugs/DB14150ApprovedCategories: Compounds used in a research, industrial, or household settingVimseltinib
go.drugbank.com/drugs/DB17520ApprovedInvestigational[L52230] It is highly selective, with a >500-fold selectivity for CSF1R over its nearest off-target kinase. … in a lower risk of off-target effects, including hepatotoxicity.
Synonyms: 2-(isopropylamino)-3-methyl-5-(6-methyl-5-((2-(1-methyl-1h-pyrazol-4-yl)pyridin-4-yl)oxy)pyridin-2-yl)pyrimidin-4(3h)-one, 3-methyl-2-((1-methylethyl)amino)-5-(6-methyl-5-((2-(1-methyl-1h-pyrazol-4-yl)-4-pyridinyl)oxy)-2-pyridinyl)-4(3h)-pyrimidinoneVonoprazan
go.drugbank.com/drugs/DB11739ApprovedInvestigational[A253702] Furthermore, vonoprazan is 350-times more potent than the proton-pump inhibitor [lansoprazole], thanks to its ability to accumulate in the gastric corpus mucosa, specifically in the parietal … [A253702] In May 2022, the FDA approved the use of vonoprazan in a co-packaged product containing amoxicillin and clarithromycin for the treatment of _H. pylori_ infection.
Synonyms: 1-[5-(2-fluorophenyl)-1-pyridin-3-ylsulfonylpyrrol-3-yl]-N-methylmethanamineNafcillin
go.drugbank.com/drugs/DB00607ApprovedInvestigationalIt may be used as a first-line therapy in Methicillin-Sensitive *Staphylococcus aureus* infections [A20360]. … It is a beta-lactamase-resistant penicillin that is indicated for the treatment of Staphylococcal infections caused by strains that are resistant to other penicillins, except those caused by MRSA.
Rupatadine
go.drugbank.com/drugs/DB11614ApprovedInvestigationalIt was approved for marketing in Canada under the tradename Rupall and comes in tablet formulation for adult use and liquid formulation for pediatric use. … Rupatadine is a dual histamine H1 receptor and platelet activating factor receptor antagonist that is used for symptomatic relief in seasonal and perennial rhinitis as well as chronic spontaneous urticaria
Products: RUPAFİN 1 MG / ML ORAL ÇÖZELTİ, 120 ML, ANTHİX 1 MG/ML PEDİATRİK ORAL ÇÖZELTİ, 120 MLNorfloxacin
go.drugbank.com/drugs/DB01059ApprovedInvestigationalA synthetic fluoroquinolone (fluoroquinolones) with broad-spectrum antibacterial activity against most gram-negative and gram-positive bacteria. Norfloxacin inhibits bacterial DNA gyrase.
Categories: Topoisomerase II InhibitorsProducts: NORFLOXACIN AL 400MG, PBAC NORFLOXACIN 200mg/ml ORAL SOLUTIONSulfur hexafluoride
go.drugbank.com/drugs/DB11104ApprovedInvestigationalin adult patients with suboptimal echocardiograms •in ultrasonography of the liver for characterization of focal liver lesions in adult and pediatric patients … Sulfur hexafluoride is an ultrasound contrast agent indicated for use •in echocardiography to opacify the left ventricular chamber and to improve the delineation of the left ventricular endocardial border
Products: SONOVUE POWDER FOR DISPERSION FOR INJECTION 8 microlitres/mlBufexamac
go.drugbank.com/drugs/DB13346ApprovedWithdrawnIt has also been used in suppositories in combination with local anaesthetics indicated for haemorrhoids. … Bufexamac was also withdrawn by the EMA in April 2010.