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Pentazocine
go.drugbank.com/drugs/DB00652ApprovedVet approvedIt is an agonist at the kappa and sigma opioid receptors and has a weak antagonist action at the mu receptor. (From AMA Drug Evaluations Annual, 1991, p97)
Mixtures: Pentazocine and naloxone, Pentazocine and naloxoneCategories: pentazocine and naloxoneEstrone sulfate
go.drugbank.com/drugs/DB04574Approvedpostmenopausal women), treatment of prostate cancer and prevention of osteoporosis. … Estrone sulfate (as estropipate) is a form of estrogen.
Mixtures: Esterified Estrogens and Methyltestosterone, Esterified Estrogens and MethyltestosteroneCategories: Hormones, Hormone Substitutes, and Hormone AntagonistsAlclofenac
go.drugbank.com/drugs/DB13167ApprovedWithdrawnIt was withdrawn from the market in the United Kingdom in 1979.
Categories: Acetic Acid Derivatives and Related Substances, Antiinflammatory and Antirheumatic ProductsLutetium Lu 177 dotatate
go.drugbank.com/drugs/DB13985ApprovedInvestigationalPatients with GEP-NETs have limited second-line treatment options after the metastasis of tumors and inadequate therapeutic response from first-line therapies. … A 177Lu-labeled somatostatin analog peptide, Lutetium Lu 177 dotatate belongs to an emerging form of treatments called Peptide Receptor Radionuclide Therapy (PRRT), which involves targeting tumours with
Categories: Indicators and Reagents, Somatostatin and AnaloguesAvibactam
go.drugbank.com/drugs/DB09060ApprovedInvestigationalThis combination was approved by the FDA on February 25, 2015 for the treatment of complicated intra-abdominal infections in combination with metronidazole, and the treatment of complicated urinary tract … As there is limited clinical safety and efficacy data, Avycaz should be reserved for patients over 18 years old who have limited or not alternative treatment options.
Papaverine
go.drugbank.com/drugs/DB01113ApprovedInvestigationalAn alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions. … The mechanism of its pharmacological actions is not clear, but it apparently can inhibit phosphodiesterases and it may have direct actions on calcium channels.
Categories: Alimentary Tract and Metabolism, Papaverine and DerivativesThiocolchicoside
go.drugbank.com/drugs/DB11582InvestigationalIt is a muscle relaxant with anti-inflammatory and analgesic effects. It has potent convulsant activity and should not be administered to individuals prone to seizures.[L1663] … Thiocolchicoside is a semi-synthetic derivative of the colchicine, a natural anti-inflammatory glycoside which originates from the flower seeds of _Superba gloriosa_.
Mixtures: ETOPLUS 400MG/8MG/20MG FİLM KAPLI TABLET, 14 ADET, MAJEZIK DUO 100MG/8MG FILM KAPLI TABLET, TABLET, 14 ADETSleeping Disorders
go.drugbank.com/conditions/DBCOND0148601Synonyms: Sleep disorders and disturbancesTerpin hydrate
go.drugbank.com/drugs/DB13163ApprovedWithdrawnIt is derived from sources such as turpentine, oregano, thyme and eucalyptus. … It was popular in the United States since the late nineteenth century, but was removed from marketed medications in the 1990s after FDA stated that "based on evidence currently available, there are inadequate
Synonyms: Terpin cis-form hydrateMoxetumomab pasudotox
go.drugbank.com/drugs/DB12688ApprovedInvestigational[A38864] MxP appears as an improved form of BL22 by the mutation of the Fv region and the antibody phage-displayed. As well the residues SSY in the heavy chain are mutated to THW. … [A38864] It was developed by Astra Zeneca and FDA approved on September 13, 2018, after being granted the status of Fast Track, Priority Review and Orphan Drug designations.[L4568]
Categories: Amino Acids, Peptides, and Proteins, Antineoplastic and Immunomodulating Agents